TITLE Calcium low threshold T type current for RD Traub, J Neurophysiol 89:909-921, 2003
COMMENT
Implemented by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu)
ENDCOMMENT
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
}
NEURON {
SUFFIX cat
NONSPECIFIC_CURRENT i : not causing [Ca2+] influx
RANGE gbar, i
}
PARAMETER {
gbar = 0.0 (mho/cm2)
v eca (mV)
}
ASSIGNED {
i (mA/cm2)
minf hinf (1)
mtau htau (ms)
}
STATE {
m h
}
BREAKPOINT {
SOLVE states METHOD cnexp
i = gbar * m * m * h * ( v - 125 )
}
INITIAL {
settables(v)
m = minf
h = hinf
m = 0
}
DERIVATIVE states {
settables(v)
m' = ( minf - m ) / mtau
h' = ( hinf - h ) / htau
}
UNITSOFF
PROCEDURE settables(v) {
TABLE minf, mtau,hinf, htau FROM -120 TO 40 WITH 641
minf = 1 / ( 1 + exp( ( -v - 56 ) / 6.2 ) )
mtau = 0.204 + 0.333 / ( exp( ( v + 15.8 ) / 18.2 ) + exp( ( - v - 131 ) / 16.7 ) )
: mtau = 0.612 + 1 / ( exp( ( v + 15.8 ) / 18.2 ) + exp( ( - v - 131 ) / 16.7 ) )
hinf = 1 / ( 1 + exp( ( v + 80 ) / 4 ) )
if( v < -81 ) {
htau = 0.333 * exp( ( v + 466 ) / 66.6 )
: htau = 1 * exp( ( v + 466 ) / 66.6 )
}else{
htau = 9.32 + 0.333 * exp( ( -v - 21 ) / 10.5 )
: htau = 27.96 + 1 * exp( ( -v - 21 ) / 10.5 )
}
}
UNITSON