TITLE leak
NEURON {
SUFFIX leak
USEION k READ ek WRITE ik
USEION na READ ena WRITE ina
USEION cl READ ecl WRITE icl VALENCE -1
USEION a READ ea WRITE ia VALENCE -1
RANGE gk, ik, gcl, icl, ga, ia, gna, ina
RANGE qk, qna, qcl, qa
}
UNITS {
(mV) = (millivolt) (mA) = (milliamp)
PI = (pi) (1)
FARADAY = 96485.309 (coul)
}
PARAMETER {
gk = 1e-5 (mho/cm2)
gna = 1e-5 (mho/cm2)
gcl = 1e-4 (mho/cm2)
ga = 0 (mho/cm2)
}
ASSIGNED {
v (mV)
ik (mA/cm2)
ek (mV)
ina (mA/cm2)
ena (mV)
icl (mA/cm2)
ecl (mV)
ia (mA/cm2)
ea (mV)
diam (um)
}
BREAKPOINT {
:SOLVE stromen METHOD after_cvode
ik = gk*(v-ek)
ina = gna*(v-ena)
icl = gcl*(v-ecl)
ia = ga*(v-ea)
SOLVE integreer METHOD sparse
}
STATE { qk qna qcl qa }
INITIAL {
ik = gk*(v-ek)
ina = gna*(v-ena)
icl = gcl*(v-ecl)
ia = ga*(v-ea)
qk = 0
qna = 0
qcl = 0
qa = 0
}
KINETIC integreer {
COMPARTMENT diam*diam*PI/4 { qna qk qcl qa}
~ qna << ((-ina*diam )*PI*(1e4)/FARADAY )
~ qk << (( -ik*diam )*PI*(1e4)/FARADAY )
~ qcl << ((-icl*diam )*PI*(1e4)/FARADAY )
~ qa << (( -ia*diam )*PI*(1e4)/FARADAY )
}
FUNCTION itot(v(mV)) {
itot=gk*(v-ek)+gna*(v-ena)+gcl*(v-ecl)+ga*(v-ea)
}
PROCEDURE stromen() {
}