#Do not define EREST_ACT or ELEAK here - they are in the .p file
# Contains maximal conductances, name of .p file, and some other parameters
# such as whether to use GHK, or whether to have real spines
import numpy as np
from moose_nerp.prototypes import util as _util
#if ghkYesNo=0 then ghk not implemented
#Note that you can use GHK without a calcium pool, it uses a default of 5e-5 Cin
if False: # param_sim.Config['ghkYN']:
ghKluge=0.35e-6
else:
ghKluge=1
#using 0.035e-9 makes NMDA calcium way too small, using single Tau calcium
ConcOut=2e-3 # mM, default for GHK is 2e-3
Temp=30 # Celsius, needed for GHK objects, some channels
neurontypes = None
morph_file = {'proto':'GP1_41comp.p','arky':'GP_arky_41comp.p'}
NAME_SOMA='soma'
#CONDUCTANCES
#Kdr is Kv2
# helper variables to index the Conductance and synapses with distance
# UNITS: meters
#soma spherical so x,y=0,0, 1e-6 means prox=soma
prox = (0,1e-6)
#med = (0,50e-6)
dist = (1e-6, 1000e-6)
axon = (0.,1., 'axon')
#If using swc files for morphology, specify structure using: _1 as soma, _2 as axon, _3 as basal dend, and _4 as apical dend,
#CONDUCTANCE VALUES - UNITS of Siemens/meter squared
# _proto for prototypical GP neuron
_proto = _util.NamedDict(
'proto',
KDr={prox: 40, dist: 7.75, axon: 77.5},
Kv3={prox: 800, dist: 140, axon: 1400}, # , med:38.4},
KvF={prox: 10, dist: 10, axon: 100}, # , med: 48},
KvS={prox: 3, dist: 3, axon: 30}, # , med: 100
KCNQ={prox: 0.04, dist: 0.04, axon: 0.04}, # , med: 2.512
NaF={prox: 40000, dist: 400, axon: 40000}, # , med: 100
NaS={prox: 0.5, dist: 0.5, axon: 0.5}, # med: 251.2,
Ca={prox: 0.1, dist: 0.06, axon: 0}, # med: 0,
HCN1={prox: 0.2, dist: 0.2, axon: 0}, # , med: 0
HCN2={prox: 0.5, dist: 0.5, axon: 0}, # med: 0,
SKCa={prox: 2, dist: 0.15, axon: 0}, # med: 0,
BKCa={prox: 0.1, dist: 0.1, axon: 0}, # med: 10,
)
_arky = _util.NamedDict(
'arky',
KDr={prox: 300, dist: 58.2, axon: 580},
Kv3={prox: 266, dist: 46.6, axon: 466},
KvF={prox: 2.5, dist: 2.5, axon: 25},
KvS={prox: 0.75, dist: 0.75, axon: 7.5},
KCNQ={prox: 0.04, dist: 0.04, axon: 0.04},
NaF={prox: 40000, dist: 400, axon: 40000},
NaS={prox: 0.15, dist: 0.15, axon: 0.5},
Ca={prox: 0.1, dist: 0.06, axon: 0},
HCN1={prox: 0.2, dist: 0.2, axon: 0},
HCN2={prox: 0.25, dist: 0.25, axon: 0},
SKCa={prox: 35, dist: 3.5, axon: 0},
BKCa={prox: 200, dist: 200, axon: 0},
)
Condset = _util.NamedDict(
'Condset',
proto = _proto,
arky=_arky,
)