//**************************************************************************** // These are the default parameters for creation of the MSP cell. This file // is usually called by hoc/nacb_main.hoc cai0_ca_ion = 0.0001 // mM, Churchill 1998 cao0_ca_ion = 5 // mM, Churchill 1998 - gives eca = 100 mV cali0_cal_ion = 0.0001 // mM, Churchill 1998 calo0_cal_ion = 5 // mM, Churchill 1998 - gives eca = 100 mV celsius = 35 // degC //ip3i_ip3_ion =0.1 //ip3o0_ip3_ion =0.1 //ip3 = 0.01 global_ra = 100 // not really sure what this is RA = 100 // ohm-cm - constant for whole cell CM = 1 // uF-cm2 - constant for whole cell G_PAS = 1.7e-5 // S/cm2 E_PAS = -70 // mV G_NAF = 1.961//1.5 // soma only G_NAFD = 0.018518 // all dends G_NAP = 7.3647e-5 // soma only G_NAPD = 2.8638e-7 // all dends G_KIR = 0.00041796 /////0.00014 // S/cm2 G_KAS = 0.012902//0.0104 // soma & prox dends; s/cm2 G_KASD = 0.00094392//0.00095142 // mid & distal dends; S/cm2 G_KAF = 0.2474 //0.225 // soma & prox dends; S/cm2 G_KAFD = 0.042944//0.020584 // mid & dist dends; S/cm2 G_KRP = 0.007298////0.001 // 0.004; S/cm2 G_BKKCA = 0.0015816 // G_SKKCA = 0.090957//0.145 CAINF = 6e-5 // mM, steady state intracell ca conc. TAUR = 43 // ms, time const of ca diffusion - Jackson 2003 CA_DRIVE = 10000 CA_PUMP = 0.0002 caNMDA = 0.1 P_CAL = 13.4e-6 // cm/s P_CALD = 13.4e-6 // cm/s P_CAL13 = 1.7e-6 // cm/s P_CAL13D = 1.7e-6 // cm/s P_CAN = 2.0e-5 // cm/s P_CAQ = 12.0e-6 // cm/s P_CAR = 5.2e-5 // cm/s P_CAT = 8e-7 // cm/s 4e-7 EK = -90 ENA = 50 NET_N = 1e10 G_AMPA = 6.64e-4 //350e-6 //8.81e-4 G_NMDA = 9.2e-5 /////12.2e-5 // 9.2e-5 G_GABA = 0.0021 //4300e-6 //0.0027 AMPA_WT = 1 NMDA_WT = 1 MGLU_WT = 1 GABA_WT = 1 DR_WT = 1 NOISE = 1 NGLU = 157 NGABA = 157 NDA = 157 NSYN = NGABA + NGLU + NDA //****************************************************************************