TITLE Potassium fast channel
: for spinal motoneuron
NEURON {
SUFFIX IKaSM
USEION k READ ek WRITE ik
RANGE gkamax, ik
}
UNITS {
(mV)=(millivolt)
(mA)=(milliamp)
}
PARAMETER {
gkamax=0 (mho/cm2)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
minf
taum (ms)
hinf
tauh (ms)
}
STATE {
m h
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik=gkamax*m*m*m*m*h*(v-ek)
}
INITIAL {
settables(v)
m=minf
h=hinf
}
DERIVATIVE states {
settables(v)
m'=(minf-m)/taum
h'=(hinf-h)/tauh
}
FUNCTION alfa(v(mV),i) {
if (i==0){
UNITSOFF
alfa=0.032*(v+64)/(1-exp(-(v+64)/6))
UNITSON
}
else if (i==1){
UNITSOFF
alfa=0.05/(1+exp((v+86)/10))
UNITSON
}
}
FUNCTION beta(v(mV),i) {
if (i==0){
UNITSOFF
beta=0.203*exp(-(v+40)/24)
UNITSON
}
else if (i==1){
UNITSOFF
beta=0.05/(1+exp(-(v+86)/10))
UNITSON
}
}
PROCEDURE settables(v (mV)) {LOCAL a,b
UNITSOFF
TABLE taum, minf, tauh, hinf FROM -100 TO 100 WITH 2000
a=alfa(v,0) b=beta(v,0)
taum=1/(a+b)
minf=a/(a+b)
a=alfa(v,1) b=beta(v,1)
tauh=1/(a+b)
hinf=a/(a+b)
UNITSON
}
UNITSON