: $Id: fvpre.mod,v 1.10 2003/07/29 23:37:22 billl Exp $
COMMENT
synapse taken from Wang, X.-J. and Buzsaki G. (1996) Gamma oscillations by
synaptic inhibition in a hippocampal interneuronal network.
J. Neurosci. 16, 6402-6413.
ENDCOMMENT
NEURON {
POINT_PROCESS gradGABA
RANGE gmax, g, i, alpha, beta, thetasyn,e, sigma
:GLOBAL thetasyn,e
NONSPECIFIC_CURRENT i
POINTER vpre
}
UNITS {
(nA) = (nanoamp)
(mV) = (millivolt)
(uS) = (microsiemens)
}
PARAMETER {
gmax = 1e-3 (uS)
alpha = 0.8 (/ms) : 1.25 ms
beta = 0.0556 (/ms) : 18 ms
e = -80 (mV) : Reserval potential
thetasyn = -40 (mV) : Activation threshold
sigma = 2
}
ASSIGNED { vpre (mV) v (mV) i (nA) g (uS)}
STATE { s }
INITIAL {
s = alpha*F(vpre)/(alpha*F(vpre)+beta)
}
BREAKPOINT {
SOLVE state METHOD cnexp
g = gmax * s
i = g*(v - e)
}
DERIVATIVE state {
s' = alpha*F(vpre)*(1-s) - beta*s
}
FUNCTION F (v1 (mV)) {
F = 1/(1 + exp(-(v1-thetasyn)/sigma))
}