<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2/version4" level="2" version="4">
<model metaid="NO" id="NO">
<annotation/>
<listOfUnitDefinitions>
<unitDefinition metaid="substance" id="substance" name="substance">
<listOfUnits>
<unit metaid="CDMT00265" kind="mole"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="volume" id="volume" name="volume">
<listOfUnits>
<unit metaid="CDMT00266" kind="litre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="area" id="area" name="area">
<listOfUnits>
<unit metaid="CDMT00267" kind="metre" exponent="2"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="length" id="length" name="length">
<listOfUnits>
<unit metaid="CDMT00268" kind="metre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="time" id="time" name="time">
<listOfUnits>
<unit metaid="CDMT00269" kind="second"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="mole_per_second" id="mole_per_second" name="mole per second">
<listOfUnits>
<unit metaid="CDMT00270" kind="mole">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Description rdf:about="#CDMT00270">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="urn:miriam:obo.unit:UO%3A0000013"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
</unit>
<unit metaid="CDMT00271" kind="second" exponent="-1">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Description rdf:about="#CDMT00271">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="urn:miriam:obo.unit:UO%3A0000010"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
</unit>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment metaid="default" id="default" size="1" units="volume"/>
</listOfCompartments>
<listOfSpecies>
<species metaid="s1" id="s1" name="NO" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s2" id="s2" name="NOS" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s5" id="s5" name="Stat-1" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s6" id="s6" name="L-Arg" compartment="default" initialAmount="0.31" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s7" id="s7" name="L-Citrulline" compartment="default" initialAmount="0.23" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s8" id="s8" name="NFKB" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s9" id="s9" name="IFNγ" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s10" id="s10" name="TNFα" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s11" id="s11" name="IL-1β" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s12" id="s12" name="IL-10" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s13" id="s13" name="IL-12" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s14" id="s14" name="MIF" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s15" id="s15" name="IRF-1" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s16" id="s16" name="PKR" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s17" id="s17" name="NO2-" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s19" id="s19" name="Macrophages" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s20" id="s20" name="Dendritic cells" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s21" id="s21" name="IL-2" compartment="default" initialAmount="4.04" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s22" id="s22" name="NK cells" compartment="default" initialAmount="0.68">
<annotation/>
</species>
<species metaid="s23" id="s23" name="Mast cells" compartment="default" initialAmount="0.64" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s24" id="s24" name="Neutrophils" compartment="default" initialAmount="0.68">
<annotation/>
</species>
<species metaid="s25" id="s25" name="Bcl-2" compartment="default" initialAmount="4.3" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s27" id="s27" name="High NO" compartment="default" initialAmount="0">
<annotation/>
</species>
<species metaid="s28" id="s28" name="Low NO" compartment="default" initialAmount="0">
<annotation/>
</species>
<species metaid="s29" id="s29" name="T-Cell" compartment="default" initialAmount="0.196" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s30" id="s30" name="T-cell accumulation" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s32" id="s32" name="P-selectin" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s34" id="s34" name="Lymphocytes" compartment="default" initialAmount="0.89" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s35" id="s35" name="Lymphocyte proliferation" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s36" id="s36" name="IkB" compartment="default" initialAmount="1" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s37" id="s37" name="IL-4" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s38" id="s38" name="VCAM-1" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s39" id="s39" name="Viral infection" compartment="default" initialAmount="0.55" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s40" id="s40" name="IL-5" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s41" id="s41" name="IL-6" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s42" id="s42" name="IL-13" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s43" id="s43" name="Eosinophils" compartment="default" initialAmount="0.32" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s45" id="s45" name="Caspase-8" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s44" id="s44" name="procaspase-8" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s46" id="s46" name="Cytochrome c " compartment="default" initialAmount="1" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s47" id="s47" name="Bid" compartment="default" initialAmount="1.09" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s48" id="s48" name="S-nitrosylated Caspase" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s49" id="s49" name="pro-IL-1β" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s50" id="s50" name="Mature IL-1β" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s51" id="s51" name="ICE" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s52" id="s52" name="Caspase-1" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s53" id="s53" name="IL-18" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s54" id="s54" name="P53" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s55" id="s55" name="Bax" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s56" id="s56" name="Caspase-3" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s57" id="s57" name="procaspase-9" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s58" id="s58" name="Caspase-9" compartment="default" initialAmount="0.11" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s59" id="s59" name="Apaf1" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s60" id="s60" name="Caspase 7" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s61" id="s61" name="Apoptosis" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s62" id="s62" name="T cell" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s63" id="s63" name="PRRs" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s64" id="s64" name="IRF-3" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
<species metaid="s65" id="s65" name="IRF-7" compartment="default" initialAmount="0" substanceUnits="substance" charge="0">
<annotation/>
</species>
</listOfSpecies>
<listOfReactions>
<reaction metaid="re1" id="re1" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00006" species="s2"/>
<speciesReference metaid="CDMT00016" species="s6"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00007" species="s1"/>
<speciesReference metaid="CDMT00017" species="s7"/>
</listOfProducts>
<kineticLaw metaid="CDMT00001">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re1 </ci>
<apply>
<times/>
<ci> kic_re1_s2 </ci>
<ci> kmc_re1_s6 </ci>
</apply>
</apply>
<ci> s2 </ci>
<ci> default </ci>
<ci> s6 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re1 </ci>
<apply>
<times/>
<ci> kic_re1_s7 </ci>
<ci> kmc_re1_s1 </ci>
</apply>
</apply>
<ci> s1 </ci>
<ci> default </ci>
<ci> s7 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
<ci> s6 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<ci> kic_re1_s2 </ci>
<ci> kmc_re1_s6 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kic_re1_s2 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
<ci> s7 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<ci> kic_re1_s7 </ci>
<ci> kmc_re1_s1 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s6 </ci>
<ci> default </ci>
</apply>
<ci> kic_re1_s6 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s7 </ci>
<ci> default </ci>
</apply>
<ci> kic_re1_s7 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_re1_s1 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re1" id="vmaf_re1" name="Forward maximal velocity of reaction re1" value="1" units="mole_per_second"/>
<parameter metaid="vmar_re1" id="vmar_re1" name="Revere maximal velocity of reaction re1" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re1_s6" id="kmc_re1_s6" name="Michaelis constant of species L-Arg in reaction re1" value="1" units="substance"/>
<parameter metaid="kmc_re1_s1" id="kmc_re1_s1" name="Michaelis constant of species NO in reaction re1" value="1" units="substance"/>
<parameter metaid="kic_re1_s1" id="kic_re1_s1" name="Inhibitory constant for species NO of reaction re1" value="1" units="substance"/>
<parameter metaid="kic_re1_s7" id="kic_re1_s7" name="Inhibitory constant for species L-Citrulline of reaction re1" value="1" units="substance"/>
<parameter metaid="kic_re1_s2" id="kic_re1_s2" name="Inhibitory constant for species NOS of reaction re1" value="1" units="substance"/>
<parameter metaid="kic_re1_s6" id="kic_re1_s6" name="Inhibitory constant for species L-Arg of reaction re1" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re5" id="re5" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00014" species="s5"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00015" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00002">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re5 </ci>
<ci> kmc_re5_s5 </ci>
</apply>
<ci> s5 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re5 </ci>
<ci> kmc_re5_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s5 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re5_s5 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re5_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re5" id="vmaf_re5" name="Forward maximal velocity of reaction re5" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re5_s5" id="kmc_re5_s5" name="Michaelis constant of species Stat-1 in reaction re5" value="1" units="substance"/>
<parameter metaid="vmar_re5" id="vmar_re5" name="Revere maximal velocity of reaction re5" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re5_s2" id="kmc_re5_s2" name="Michaelis constant of species NOS in reaction re5" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re6" id="re6" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00003" species="s10"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00004" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00005">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re6 </ci>
<ci> kmc_re6_s10 </ci>
</apply>
<ci> s10 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re6 </ci>
<ci> kmc_re6_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s10 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re6_s10 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re6_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re6" id="vmaf_re6" name="Forward maximal velocity of reaction re6" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re6_s10" id="kmc_re6_s10" name="Michaelis constant of species TNFα in reaction re6" value="1" units="substance"/>
<parameter metaid="vmar_re6" id="vmar_re6" name="Revere maximal velocity of reaction re6" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re6_s2" id="kmc_re6_s2" name="Michaelis constant of species NOS in reaction re6" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re7" id="re7" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00008" species="s9"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00009" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00010">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re7 </ci>
<ci> kmc_re7_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re7 </ci>
<ci> kmc_re7_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re7_s9 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re7_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re7" id="vmaf_re7" name="Forward maximal velocity of reaction re7" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re7_s9" id="kmc_re7_s9" name="Michaelis constant of species IFNγ in reaction re7" value="1" units="substance"/>
<parameter metaid="vmar_re7" id="vmar_re7" name="Revere maximal velocity of reaction re7" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re7_s2" id="kmc_re7_s2" name="Michaelis constant of species NOS in reaction re7" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re8" id="re8" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00011" species="s11"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00012" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00013">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re8 </ci>
<ci> kmc_re8_s11 </ci>
</apply>
<ci> s11 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re8 </ci>
<ci> kmc_re8_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s11 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re8_s11 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re8_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re8" id="vmaf_re8" name="Forward maximal velocity of reaction re8" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re8_s11" id="kmc_re8_s11" name="Michaelis constant of species IL-1β in reaction re8" value="1" units="substance"/>
<parameter metaid="vmar_re8" id="vmar_re8" name="Revere maximal velocity of reaction re8" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re8_s2" id="kmc_re8_s2" name="Michaelis constant of species NOS in reaction re8" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re9" id="re9" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00018" species="s12"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00019" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00020">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re9 </ci>
<ci> kmc_re9_s12 </ci>
</apply>
<ci> s12 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re9 </ci>
<ci> kmc_re9_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s12 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re9_s12 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re9_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re9" id="vmaf_re9" name="Forward maximal velocity of reaction re9" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re9_s12" id="kmc_re9_s12" name="Michaelis constant of species IL-10 in reaction re9" value="1" units="substance"/>
<parameter metaid="vmar_re9" id="vmar_re9" name="Revere maximal velocity of reaction re9" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re9_s2" id="kmc_re9_s2" name="Michaelis constant of species NOS in reaction re9" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re10" id="re10" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00021" species="s13"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00022" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00023">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re10 </ci>
<ci> kmc_re10_s13 </ci>
</apply>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re10 </ci>
<ci> kmc_re10_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re10_s13 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re10_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re10" id="vmaf_re10" name="Forward maximal velocity of reaction re10" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re10_s13" id="kmc_re10_s13" name="Michaelis constant of species IL-12 in reaction re10" value="1" units="substance"/>
<parameter metaid="vmar_re10" id="vmar_re10" name="Revere maximal velocity of reaction re10" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re10_s2" id="kmc_re10_s2" name="Michaelis constant of species NOS in reaction re10" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re11" id="re11" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00024" species="s14"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00025" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00026">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re11 </ci>
<ci> kmc_re11_s14 </ci>
</apply>
<ci> s14 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re11 </ci>
<ci> kmc_re11_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s14 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re11_s14 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re11_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re11" id="vmaf_re11" name="Forward maximal velocity of reaction re11" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re11_s14" id="kmc_re11_s14" name="Michaelis constant of species MIF in reaction re11" value="1" units="substance"/>
<parameter metaid="vmar_re11" id="vmar_re11" name="Revere maximal velocity of reaction re11" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re11_s2" id="kmc_re11_s2" name="Michaelis constant of species NOS in reaction re11" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re12" id="re12" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00028" species="s8"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00029" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00027">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re12 </ci>
<ci> kmc_re12_s8 </ci>
</apply>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re12 </ci>
<ci> kmc_re12_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re12_s8 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re12_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re12" id="vmaf_re12" name="Forward maximal velocity of reaction re12" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re12_s8" id="kmc_re12_s8" name="Michaelis constant of species NFKB in reaction re12" value="1" units="substance"/>
<parameter metaid="vmar_re12" id="vmar_re12" name="Revere maximal velocity of reaction re12" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re12_s2" id="kmc_re12_s2" name="Michaelis constant of species NOS in reaction re12" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re13" id="re13" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00030" species="s16"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00031" species="s15"/>
</listOfProducts>
<kineticLaw metaid="CDMT00032">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re13 </ci>
<ci> kmc_re13_s16 </ci>
</apply>
<ci> s16 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re13 </ci>
<ci> kmc_re13_s15 </ci>
</apply>
<ci> s15 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s16 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re13_s16 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re13_s15 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re13" id="vmaf_re13" name="Forward maximal velocity of reaction re13" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re13_s16" id="kmc_re13_s16" name="Michaelis constant of species PKR in reaction re13" value="1" units="substance"/>
<parameter metaid="vmar_re13" id="vmar_re13" name="Revere maximal velocity of reaction re13" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re13_s15" id="kmc_re13_s15" name="Michaelis constant of species IRF-1 in reaction re13" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re14" id="re14" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00033" species="s16"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00034" species="s8"/>
</listOfProducts>
<kineticLaw metaid="CDMT00035">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re14 </ci>
<ci> kmc_re14_s16 </ci>
</apply>
<ci> s16 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re14 </ci>
<ci> kmc_re14_s8 </ci>
</apply>
<ci> s8 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s16 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re14_s16 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re14_s8 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re14" id="vmaf_re14" name="Forward maximal velocity of reaction re14" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re14_s16" id="kmc_re14_s16" name="Michaelis constant of species PKR in reaction re14" value="1" units="substance"/>
<parameter metaid="vmar_re14" id="vmar_re14" name="Revere maximal velocity of reaction re14" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re14_s8" id="kmc_re14_s8" name="Michaelis constant of species NFKB in reaction re14" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re15" id="re15" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00036" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00037" species="s17"/>
</listOfProducts>
<kineticLaw metaid="CDMT00038">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re15 </ci>
<ci> kmc_re15_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re15 </ci>
<ci> kmc_re15_s17 </ci>
</apply>
<ci> s17 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re15_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s17 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re15_s17 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re15" id="vmaf_re15" name="Forward maximal velocity of reaction re15" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re15_s1" id="kmc_re15_s1" name="Michaelis constant of species NO in reaction re15" value="1" units="substance"/>
<parameter metaid="vmar_re15" id="vmar_re15" name="Revere maximal velocity of reaction re15" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re15_s17" id="kmc_re15_s17" name="Michaelis constant of species NO2- in reaction re15" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re16" id="re16" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00039" species="s20"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00040" species="s21"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00068" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00041">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re16 </ci>
<ci> kmc_re16_s20 </ci>
</apply>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re16 </ci>
<ci> kmc_re16_s21 </ci>
</apply>
<ci> s21 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re16_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re16_s20 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s21 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re16_s21 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re16_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re16" id="vmaf_re16" name="Forward maximal velocity of reaction re16" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re16_s20" id="kmc_re16_s20" name="Michaelis constant of species Dendritic cells in reaction re16" value="1" units="substance"/>
<parameter metaid="vmar_re16" id="vmar_re16" name="Revere maximal velocity of reaction re16" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re16_s21" id="kmc_re16_s21" name="Michaelis constant of species IL-2 in reaction re16" value="1" units="substance"/>
<parameter metaid="kic_1_re16_s1" id="kic_1_re16_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re16" value="1" units="substance"/>
<parameter metaid="kic_2_re16_s1" id="kic_2_re16_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re16" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re17" id="re17" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00042" species="s19"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00043" species="s21"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00069" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00044">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re17 </ci>
<ci> kmc_re17_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re17 </ci>
<ci> kmc_re17_s21 </ci>
</apply>
<ci> s21 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re17_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re17_s19 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s21 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re17_s21 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re17_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re17" id="vmaf_re17" name="Forward maximal velocity of reaction re17" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re17_s19" id="kmc_re17_s19" name="Michaelis constant of species Macrophages in reaction re17" value="1" units="substance"/>
<parameter metaid="vmar_re17" id="vmar_re17" name="Revere maximal velocity of reaction re17" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re17_s21" id="kmc_re17_s21" name="Michaelis constant of species IL-2 in reaction re17" value="1" units="substance"/>
<parameter metaid="kic_1_re17_s1" id="kic_1_re17_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re17" value="1" units="substance"/>
<parameter metaid="kic_2_re17_s1" id="kic_2_re17_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re17" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re18" id="re18" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00045" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00046" species="s25"/>
</listOfProducts>
<kineticLaw metaid="CDMT00047">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re18 </ci>
<ci> kmc_re18_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re18 </ci>
<ci> kmc_re18_s25 </ci>
</apply>
<ci> s25 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re18_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re18_s25 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re18" id="vmaf_re18" name="Forward maximal velocity of reaction re18" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re18_s1" id="kmc_re18_s1" name="Michaelis constant of species NO in reaction re18" value="1" units="substance"/>
<parameter metaid="vmar_re18" id="vmar_re18" name="Revere maximal velocity of reaction re18" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re18_s25" id="kmc_re18_s25" name="Michaelis constant of species Bcl-2 in reaction re18" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re19" id="re19" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00048" species="s62"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00049" species="s61"/>
</listOfProducts>
<kineticLaw metaid="CDMT00050">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re19 </ci>
<ci> kmc_re19_s62 </ci>
</apply>
<ci> s62 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re19 </ci>
<ci> kmc_re19_s61 </ci>
</apply>
<ci> s61 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s62 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re19_s62 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s61 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re19_s61 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re19" id="vmaf_re19" name="Forward maximal velocity of reaction re19" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re19_s62" id="kmc_re19_s62" name="Michaelis constant of species T cell in reaction re19" value="1" units="substance"/>
<parameter metaid="vmar_re19" id="vmar_re19" name="Revere maximal velocity of reaction re19" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re19_s61" id="kmc_re19_s61" name="Michaelis constant of species Apoptosis in reaction re19" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re20" id="re20" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00051" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00052" species="s30"/>
</listOfProducts>
<kineticLaw metaid="CDMT00053">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re20 </ci>
<ci> kmc_re20_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re20 </ci>
<ci> kmc_re20_s30 </ci>
</apply>
<ci> s30 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re20_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s30 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re20_s30 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re20" id="vmaf_re20" name="Forward maximal velocity of reaction re20" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re20_s29" id="kmc_re20_s29" name="Michaelis constant of species T-Cell in reaction re20" value="1" units="substance"/>
<parameter metaid="vmar_re20" id="vmar_re20" name="Revere maximal velocity of reaction re20" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re20_s30" id="kmc_re20_s30" name="Michaelis constant of species T-cell accumulation in reaction re20" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re22" id="re22" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00054" species="s32"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00055" species="s29"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00056" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00057">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re22 </ci>
<ci> kmc_re22_s32 </ci>
</apply>
<ci> s32 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re22 </ci>
<ci> kmc_re22_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re22_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s32 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re22_s32 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re22_s29 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re22_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re22" id="vmaf_re22" name="Forward maximal velocity of reaction re22" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re22_s32" id="kmc_re22_s32" name="Michaelis constant of species P-selectin in reaction re22" value="1" units="substance"/>
<parameter metaid="vmar_re22" id="vmar_re22" name="Revere maximal velocity of reaction re22" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re22_s29" id="kmc_re22_s29" name="Michaelis constant of species T-Cell in reaction re22" value="1" units="substance"/>
<parameter metaid="kic_1_re22_s1" id="kic_1_re22_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re22" value="1" units="substance"/>
<parameter metaid="kic_2_re22_s1" id="kic_2_re22_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re22" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re23" id="re23" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00058" species="s34"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00059" species="s35"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00060" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00061">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re23 </ci>
<ci> kmc_re23_s34 </ci>
</apply>
<ci> s34 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re23 </ci>
<ci> kmc_re23_s35 </ci>
</apply>
<ci> s35 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re23_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s34 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re23_s34 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s35 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re23_s35 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re23_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re23" id="vmaf_re23" name="Forward maximal velocity of reaction re23" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re23_s34" id="kmc_re23_s34" name="Michaelis constant of species Lymphocytes in reaction re23" value="1" units="substance"/>
<parameter metaid="vmar_re23" id="vmar_re23" name="Revere maximal velocity of reaction re23" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re23_s35" id="kmc_re23_s35" name="Michaelis constant of species Lymphocyte proliferation in reaction re23" value="1" units="substance"/>
<parameter metaid="kic_1_re23_s1" id="kic_1_re23_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re23" value="1" units="substance"/>
<parameter metaid="kic_2_re23_s1" id="kic_2_re23_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re23" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re24" id="re24" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00062" species="s19"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00063" species="s13"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00064" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00065">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re24 </ci>
<ci> kmc_re24_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re24 </ci>
<ci> kmc_re24_s13 </ci>
</apply>
<ci> s13 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re24_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re24_s19 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re24_s13 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re24_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re24" id="vmaf_re24" name="Forward maximal velocity of reaction re24" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re24_s19" id="kmc_re24_s19" name="Michaelis constant of species Macrophages in reaction re24" value="1" units="substance"/>
<parameter metaid="vmar_re24" id="vmar_re24" name="Revere maximal velocity of reaction re24" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re24_s13" id="kmc_re24_s13" name="Michaelis constant of species IL-12 in reaction re24" value="1" units="substance"/>
<parameter metaid="kic_1_re24_s1" id="kic_1_re24_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re24" value="1" units="substance"/>
<parameter metaid="kic_2_re24_s1" id="kic_2_re24_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re24" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re25" id="re25" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00066" species="s13"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00067" species="s29"/>
</listOfProducts>
<kineticLaw metaid="CDMT00070">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re25 </ci>
<ci> kmc_re25_s13 </ci>
</apply>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re25 </ci>
<ci> kmc_re25_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re25_s13 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re25_s29 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re25" id="vmaf_re25" name="Forward maximal velocity of reaction re25" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re25_s13" id="kmc_re25_s13" name="Michaelis constant of species IL-12 in reaction re25" value="1" units="substance"/>
<parameter metaid="vmar_re25" id="vmar_re25" name="Revere maximal velocity of reaction re25" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re25_s29" id="kmc_re25_s29" name="Michaelis constant of species T-Cell in reaction re25" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re26" id="re26" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00071" species="s19"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00072" species="s10"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00073" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00074">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re26 </ci>
<ci> kmc_re26_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re26 </ci>
<ci> kmc_re26_s10 </ci>
</apply>
<ci> s10 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re26_s19 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s10 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re26_s10 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re26" id="vmaf_re26" name="Forward maximal velocity of reaction re26" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re26_s19" id="kmc_re26_s19" name="Michaelis constant of species Macrophages in reaction re26" value="1" units="substance"/>
<parameter metaid="vmar_re26" id="vmar_re26" name="Revere maximal velocity of reaction re26" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re26_s10" id="kmc_re26_s10" name="Michaelis constant of species TNFα in reaction re26" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re27" id="re27" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00075" species="s36"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00076" species="s8"/>
</listOfProducts>
<kineticLaw metaid="CDMT00077">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re27 </ci>
<ci> kmc_re27_s36 </ci>
</apply>
<ci> s36 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re27 </ci>
<ci> kmc_re27_s8 </ci>
</apply>
<ci> s8 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s36 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re27_s36 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re27_s8 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re27" id="vmaf_re27" name="Forward maximal velocity of reaction re27" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re27_s36" id="kmc_re27_s36" name="Michaelis constant of species IkB in reaction re27" value="1" units="substance"/>
<parameter metaid="vmar_re27" id="vmar_re27" name="Revere maximal velocity of reaction re27" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re27_s8" id="kmc_re27_s8" name="Michaelis constant of species NFKB in reaction re27" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re28" id="re28" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00078" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00079" species="s36"/>
</listOfProducts>
<kineticLaw metaid="CDMT00080">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re28 </ci>
<ci> kmc_re28_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re28 </ci>
<ci> kmc_re28_s36 </ci>
</apply>
<ci> s36 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re28_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s36 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re28_s36 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re28" id="vmaf_re28" name="Forward maximal velocity of reaction re28" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re28_s1" id="kmc_re28_s1" name="Michaelis constant of species NO in reaction re28" value="1" units="substance"/>
<parameter metaid="vmar_re28" id="vmar_re28" name="Revere maximal velocity of reaction re28" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re28_s36" id="kmc_re28_s36" name="Michaelis constant of species IkB in reaction re28" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re29" id="re29" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00081" species="s8"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00082" species="s10"/>
</listOfProducts>
<kineticLaw metaid="CDMT00083">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re29 </ci>
<ci> kmc_re29_s8 </ci>
</apply>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re29 </ci>
<ci> kmc_re29_s10 </ci>
</apply>
<ci> s10 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s8 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re29_s8 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s10 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re29_s10 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re29" id="vmaf_re29" name="Forward maximal velocity of reaction re29" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re29_s8" id="kmc_re29_s8" name="Michaelis constant of species NFKB in reaction re29" value="1" units="substance"/>
<parameter metaid="vmar_re29" id="vmar_re29" name="Revere maximal velocity of reaction re29" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re29_s10" id="kmc_re29_s10" name="Michaelis constant of species TNFα in reaction re29" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re30" id="re30" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00084" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00085" species="s21"/>
</listOfProducts>
<kineticLaw metaid="CDMT00086">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re30 </ci>
<ci> kmc_re30_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re30 </ci>
<ci> kmc_re30_s21 </ci>
</apply>
<ci> s21 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re30_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s21 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re30_s21 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re30" id="vmaf_re30" name="Forward maximal velocity of reaction re30" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re30_s29" id="kmc_re30_s29" name="Michaelis constant of species T-Cell in reaction re30" value="1" units="substance"/>
<parameter metaid="vmar_re30" id="vmar_re30" name="Revere maximal velocity of reaction re30" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re30_s21" id="kmc_re30_s21" name="Michaelis constant of species IL-2 in reaction re30" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re31" id="re31" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00087" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00088" species="s9"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00089" species="s1"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00090">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re31 </ci>
<ci> kmc_re31_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re31 </ci>
<ci> kmc_re31_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re31_s1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re31_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re31_s9 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re31_s1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re31" id="vmaf_re31" name="Forward maximal velocity of reaction re31" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re31_s29" id="kmc_re31_s29" name="Michaelis constant of species T-Cell in reaction re31" value="1" units="substance"/>
<parameter metaid="vmar_re31" id="vmar_re31" name="Revere maximal velocity of reaction re31" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re31_s9" id="kmc_re31_s9" name="Michaelis constant of species IFNγ in reaction re31" value="1" units="substance"/>
<parameter metaid="kic_1_re31_s1" id="kic_1_re31_s1" name="Inhibitory constant for species NOwith 1 binding positions of reaction re31" value="1" units="substance"/>
<parameter metaid="kic_2_re31_s1" id="kic_2_re31_s1" name="Inhibitory constant for species NOwith 2 binding positions of reaction re31" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re32" id="re32" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00091" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00092" species="s37"/>
</listOfProducts>
<kineticLaw metaid="CDMT00093">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re32 </ci>
<ci> kmc_re32_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re32 </ci>
<ci> kmc_re32_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re32_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re32_s37 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re32" id="vmaf_re32" name="Forward maximal velocity of reaction re32" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re32_s1" id="kmc_re32_s1" name="Michaelis constant of species NO in reaction re32" value="1" units="substance"/>
<parameter metaid="vmar_re32" id="vmar_re32" name="Revere maximal velocity of reaction re32" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re32_s37" id="kmc_re32_s37" name="Michaelis constant of species IL-4 in reaction re32" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re33" id="re33" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00094" species="s37"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00095" species="s29"/>
</listOfProducts>
<kineticLaw metaid="CDMT00096">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re33 </ci>
<ci> kmc_re33_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re33 </ci>
<ci> kmc_re33_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re33_s37 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re33_s29 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re33" id="vmaf_re33" name="Forward maximal velocity of reaction re33" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re33_s37" id="kmc_re33_s37" name="Michaelis constant of species IL-4 in reaction re33" value="1" units="substance"/>
<parameter metaid="vmar_re33" id="vmar_re33" name="Revere maximal velocity of reaction re33" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re33_s29" id="kmc_re33_s29" name="Michaelis constant of species T-Cell in reaction re33" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re34" id="re34" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00097" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00098" species="s37"/>
</listOfProducts>
<kineticLaw metaid="CDMT00099">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re34 </ci>
<ci> kmc_re34_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re34 </ci>
<ci> kmc_re34_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re34_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re34_s37 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re34" id="vmaf_re34" name="Forward maximal velocity of reaction re34" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re34_s29" id="kmc_re34_s29" name="Michaelis constant of species T-Cell in reaction re34" value="1" units="substance"/>
<parameter metaid="vmar_re34" id="vmar_re34" name="Revere maximal velocity of reaction re34" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re34_s37" id="kmc_re34_s37" name="Michaelis constant of species IL-4 in reaction re34" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re35" id="re35" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00100" species="s9"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00101" species="s19"/>
</listOfProducts>
<kineticLaw metaid="CDMT00102">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re35 </ci>
<ci> kmc_re35_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re35 </ci>
<ci> kmc_re35_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re35_s9 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re35_s19 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re35" id="vmaf_re35" name="Forward maximal velocity of reaction re35" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re35_s9" id="kmc_re35_s9" name="Michaelis constant of species IFNγ in reaction re35" value="1" units="substance"/>
<parameter metaid="vmar_re35" id="vmar_re35" name="Revere maximal velocity of reaction re35" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re35_s19" id="kmc_re35_s19" name="Michaelis constant of species Macrophages in reaction re35" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re36" id="re36" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00103" species="s37"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00104" species="s38"/>
</listOfProducts>
<kineticLaw metaid="CDMT00105">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re36 </ci>
<ci> kmc_re36_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re36 </ci>
<ci> kmc_re36_s38 </ci>
</apply>
<ci> s38 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re36_s37 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s38 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re36_s38 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re36" id="vmaf_re36" name="Forward maximal velocity of reaction re36" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re36_s37" id="kmc_re36_s37" name="Michaelis constant of species IL-4 in reaction re36" value="1" units="substance"/>
<parameter metaid="vmar_re36" id="vmar_re36" name="Revere maximal velocity of reaction re36" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re36_s38" id="kmc_re36_s38" name="Michaelis constant of species VCAM-1 in reaction re36" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re37" id="re37" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00106" species="s19"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00107" species="s1"/>
</listOfProducts>
<kineticLaw metaid="CDMT00108">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re37 </ci>
<ci> kmc_re37_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re37 </ci>
<ci> kmc_re37_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re37_s19 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re37_s1 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re37" id="vmaf_re37" name="Forward maximal velocity of reaction re37" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re37_s19" id="kmc_re37_s19" name="Michaelis constant of species Macrophages in reaction re37" value="1" units="substance"/>
<parameter metaid="vmar_re37" id="vmar_re37" name="Revere maximal velocity of reaction re37" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re37_s1" id="kmc_re37_s1" name="Michaelis constant of species NO in reaction re37" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re38" id="re38" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00109" species="s19"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00110" species="s11"/>
</listOfProducts>
<kineticLaw metaid="CDMT00111">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re38 </ci>
<ci> kmc_re38_s19 </ci>
</apply>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re38 </ci>
<ci> kmc_re38_s11 </ci>
</apply>
<ci> s11 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s19 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re38_s19 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s11 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re38_s11 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re38" id="vmaf_re38" name="Forward maximal velocity of reaction re38" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re38_s19" id="kmc_re38_s19" name="Michaelis constant of species Macrophages in reaction re38" value="1" units="substance"/>
<parameter metaid="vmar_re38" id="vmar_re38" name="Revere maximal velocity of reaction re38" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re38_s11" id="kmc_re38_s11" name="Michaelis constant of species IL-1β in reaction re38" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re39" id="re39" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00112" species="s39"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00113" species="s2"/>
</listOfProducts>
<kineticLaw metaid="CDMT00114">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re39 </ci>
<ci> kmc_re39_s39 </ci>
</apply>
<ci> s39 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re39 </ci>
<ci> kmc_re39_s2 </ci>
</apply>
<ci> s2 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s39 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re39_s39 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s2 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re39_s2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re39" id="vmaf_re39" name="Forward maximal velocity of reaction re39" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re39_s39" id="kmc_re39_s39" name="Michaelis constant of species Viral infection in reaction re39" value="1" units="substance"/>
<parameter metaid="vmar_re39" id="vmar_re39" name="Revere maximal velocity of reaction re39" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re39_s2" id="kmc_re39_s2" name="Michaelis constant of species NOS in reaction re39" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re40" id="re40" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00115" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00116" species="s40"/>
</listOfProducts>
<kineticLaw metaid="CDMT00117">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re40 </ci>
<ci> kmc_re40_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re40 </ci>
<ci> kmc_re40_s40 </ci>
</apply>
<ci> s40 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re40_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s40 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re40_s40 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re40" id="vmaf_re40" name="Forward maximal velocity of reaction re40" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re40_s29" id="kmc_re40_s29" name="Michaelis constant of species T-Cell in reaction re40" value="1" units="substance"/>
<parameter metaid="vmar_re40" id="vmar_re40" name="Revere maximal velocity of reaction re40" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re40_s40" id="kmc_re40_s40" name="Michaelis constant of species IL-5 in reaction re40" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re41" id="re41" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00118" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00119" species="s41"/>
</listOfProducts>
<kineticLaw metaid="CDMT00120">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re41 </ci>
<ci> kmc_re41_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re41 </ci>
<ci> kmc_re41_s41 </ci>
</apply>
<ci> s41 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re41_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re41_s41 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re41" id="vmaf_re41" name="Forward maximal velocity of reaction re41" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re41_s29" id="kmc_re41_s29" name="Michaelis constant of species T-Cell in reaction re41" value="1" units="substance"/>
<parameter metaid="vmar_re41" id="vmar_re41" name="Revere maximal velocity of reaction re41" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re41_s41" id="kmc_re41_s41" name="Michaelis constant of species IL-6 in reaction re41" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re42" id="re42" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00121" species="s29"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00122" species="s42"/>
</listOfProducts>
<kineticLaw metaid="CDMT00123">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re42 </ci>
<ci> kmc_re42_s29 </ci>
</apply>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re42 </ci>
<ci> kmc_re42_s42 </ci>
</apply>
<ci> s42 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s29 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re42_s29 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s42 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re42_s42 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re42" id="vmaf_re42" name="Forward maximal velocity of reaction re42" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re42_s29" id="kmc_re42_s29" name="Michaelis constant of species T-Cell in reaction re42" value="1" units="substance"/>
<parameter metaid="vmar_re42" id="vmar_re42" name="Revere maximal velocity of reaction re42" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re42_s42" id="kmc_re42_s42" name="Michaelis constant of species IL-13 in reaction re42" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re45" id="re45" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00124" species="s37"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00125" species="s23"/>
</listOfProducts>
<kineticLaw metaid="CDMT00126">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re45 </ci>
<ci> kmc_re45_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re45 </ci>
<ci> kmc_re45_s23 </ci>
</apply>
<ci> s23 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re45_s37 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s23 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re45_s23 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re45" id="vmaf_re45" name="Forward maximal velocity of reaction re45" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re45_s37" id="kmc_re45_s37" name="Michaelis constant of species IL-4 in reaction re45" value="1" units="substance"/>
<parameter metaid="vmar_re45" id="vmar_re45" name="Revere maximal velocity of reaction re45" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re45_s23" id="kmc_re45_s23" name="Michaelis constant of species Mast cells in reaction re45" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re46" id="re46" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00127" species="s37"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00128" species="s43"/>
</listOfProducts>
<kineticLaw metaid="CDMT00129">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re46 </ci>
<ci> kmc_re46_s37 </ci>
</apply>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re46 </ci>
<ci> kmc_re46_s43 </ci>
</apply>
<ci> s43 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s37 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re46_s37 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s43 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re46_s43 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re46" id="vmaf_re46" name="Forward maximal velocity of reaction re46" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re46_s37" id="kmc_re46_s37" name="Michaelis constant of species IL-4 in reaction re46" value="1" units="substance"/>
<parameter metaid="vmar_re46" id="vmar_re46" name="Revere maximal velocity of reaction re46" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re46_s43" id="kmc_re46_s43" name="Michaelis constant of species Eosinophils in reaction re46" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re47" id="re47" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00130" species="s40"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00131" species="s23"/>
</listOfProducts>
<kineticLaw metaid="CDMT00132">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re47 </ci>
<ci> kmc_re47_s40 </ci>
</apply>
<ci> s40 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re47 </ci>
<ci> kmc_re47_s23 </ci>
</apply>
<ci> s23 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s40 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re47_s40 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s23 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re47_s23 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re47" id="vmaf_re47" name="Forward maximal velocity of reaction re47" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re47_s40" id="kmc_re47_s40" name="Michaelis constant of species IL-5 in reaction re47" value="1" units="substance"/>
<parameter metaid="vmar_re47" id="vmar_re47" name="Revere maximal velocity of reaction re47" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re47_s23" id="kmc_re47_s23" name="Michaelis constant of species Mast cells in reaction re47" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re48" id="re48" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00133" species="s40"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00134" species="s43"/>
</listOfProducts>
<kineticLaw metaid="CDMT00135">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re48 </ci>
<ci> kmc_re48_s40 </ci>
</apply>
<ci> s40 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re48 </ci>
<ci> kmc_re48_s43 </ci>
</apply>
<ci> s43 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s40 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re48_s40 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s43 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re48_s43 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re48" id="vmaf_re48" name="Forward maximal velocity of reaction re48" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re48_s40" id="kmc_re48_s40" name="Michaelis constant of species IL-5 in reaction re48" value="1" units="substance"/>
<parameter metaid="vmar_re48" id="vmar_re48" name="Revere maximal velocity of reaction re48" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re48_s43" id="kmc_re48_s43" name="Michaelis constant of species Eosinophils in reaction re48" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re49" id="re49" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00136" species="s41"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00137" species="s23"/>
</listOfProducts>
<kineticLaw metaid="CDMT00138">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re49 </ci>
<ci> kmc_re49_s41 </ci>
</apply>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re49 </ci>
<ci> kmc_re49_s23 </ci>
</apply>
<ci> s23 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re49_s41 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s23 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re49_s23 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re49" id="vmaf_re49" name="Forward maximal velocity of reaction re49" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re49_s41" id="kmc_re49_s41" name="Michaelis constant of species IL-6 in reaction re49" value="1" units="substance"/>
<parameter metaid="vmar_re49" id="vmar_re49" name="Revere maximal velocity of reaction re49" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re49_s23" id="kmc_re49_s23" name="Michaelis constant of species Mast cells in reaction re49" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re50" id="re50" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00139" species="s41"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00140" species="s43"/>
</listOfProducts>
<kineticLaw metaid="CDMT00141">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re50 </ci>
<ci> kmc_re50_s41 </ci>
</apply>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re50 </ci>
<ci> kmc_re50_s43 </ci>
</apply>
<ci> s43 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re50_s41 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s43 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re50_s43 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re50" id="vmaf_re50" name="Forward maximal velocity of reaction re50" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re50_s41" id="kmc_re50_s41" name="Michaelis constant of species IL-6 in reaction re50" value="1" units="substance"/>
<parameter metaid="vmar_re50" id="vmar_re50" name="Revere maximal velocity of reaction re50" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re50_s43" id="kmc_re50_s43" name="Michaelis constant of species Eosinophils in reaction re50" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re51" id="re51" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00142" species="s42"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00143" species="s23"/>
</listOfProducts>
<kineticLaw metaid="CDMT00144">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re51 </ci>
<ci> kmc_re51_s42 </ci>
</apply>
<ci> s42 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re51 </ci>
<ci> kmc_re51_s23 </ci>
</apply>
<ci> s23 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s42 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re51_s42 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s23 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re51_s23 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re51" id="vmaf_re51" name="Forward maximal velocity of reaction re51" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re51_s42" id="kmc_re51_s42" name="Michaelis constant of species IL-13 in reaction re51" value="1" units="substance"/>
<parameter metaid="vmar_re51" id="vmar_re51" name="Revere maximal velocity of reaction re51" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re51_s23" id="kmc_re51_s23" name="Michaelis constant of species Mast cells in reaction re51" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re52" id="re52" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00145" species="s42"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00146" species="s43"/>
</listOfProducts>
<kineticLaw metaid="CDMT00147">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re52 </ci>
<ci> kmc_re52_s42 </ci>
</apply>
<ci> s42 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re52 </ci>
<ci> kmc_re52_s43 </ci>
</apply>
<ci> s43 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s42 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re52_s42 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s43 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re52_s43 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re52" id="vmaf_re52" name="Forward maximal velocity of reaction re52" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re52_s42" id="kmc_re52_s42" name="Michaelis constant of species IL-13 in reaction re52" value="1" units="substance"/>
<parameter metaid="vmar_re52" id="vmar_re52" name="Revere maximal velocity of reaction re52" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re52_s43" id="kmc_re52_s43" name="Michaelis constant of species Eosinophils in reaction re52" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re53" id="re53" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00148" species="s20"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00149" species="s13"/>
</listOfProducts>
<kineticLaw metaid="CDMT00150">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re53 </ci>
<ci> kmc_re53_s20 </ci>
</apply>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re53 </ci>
<ci> kmc_re53_s13 </ci>
</apply>
<ci> s13 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re53_s20 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re53_s13 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re53" id="vmaf_re53" name="Forward maximal velocity of reaction re53" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re53_s20" id="kmc_re53_s20" name="Michaelis constant of species Dendritic cells in reaction re53" value="1" units="substance"/>
<parameter metaid="vmar_re53" id="vmar_re53" name="Revere maximal velocity of reaction re53" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re53_s13" id="kmc_re53_s13" name="Michaelis constant of species IL-12 in reaction re53" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re54" id="re54" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00151" species="s20"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00152" species="s10"/>
</listOfProducts>
<kineticLaw metaid="CDMT00153">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re54 </ci>
<ci> kmc_re54_s20 </ci>
</apply>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re54 </ci>
<ci> kmc_re54_s10 </ci>
</apply>
<ci> s10 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re54_s20 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s10 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re54_s10 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re54" id="vmaf_re54" name="Forward maximal velocity of reaction re54" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re54_s20" id="kmc_re54_s20" name="Michaelis constant of species Dendritic cells in reaction re54" value="1" units="substance"/>
<parameter metaid="vmar_re54" id="vmar_re54" name="Revere maximal velocity of reaction re54" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re54_s10" id="kmc_re54_s10" name="Michaelis constant of species TNFα in reaction re54" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re55" id="re55" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00154" species="s20"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00155" species="s41"/>
</listOfProducts>
<kineticLaw metaid="CDMT00156">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re55 </ci>
<ci> kmc_re55_s20 </ci>
</apply>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re55 </ci>
<ci> kmc_re55_s41 </ci>
</apply>
<ci> s41 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re55_s20 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s41 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re55_s41 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re55" id="vmaf_re55" name="Forward maximal velocity of reaction re55" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re55_s20" id="kmc_re55_s20" name="Michaelis constant of species Dendritic cells in reaction re55" value="1" units="substance"/>
<parameter metaid="vmar_re55" id="vmar_re55" name="Revere maximal velocity of reaction re55" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re55_s41" id="kmc_re55_s41" name="Michaelis constant of species IL-6 in reaction re55" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re56" id="re56" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00157" species="s20"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00158" species="s9"/>
</listOfProducts>
<kineticLaw metaid="CDMT00159">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re56 </ci>
<ci> kmc_re56_s20 </ci>
</apply>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re56 </ci>
<ci> kmc_re56_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s20 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re56_s20 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re56_s9 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re56" id="vmaf_re56" name="Forward maximal velocity of reaction re56" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re56_s20" id="kmc_re56_s20" name="Michaelis constant of species Dendritic cells in reaction re56" value="1" units="substance"/>
<parameter metaid="vmar_re56" id="vmar_re56" name="Revere maximal velocity of reaction re56" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re56_s9" id="kmc_re56_s9" name="Michaelis constant of species IFNγ in reaction re56" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re57" id="re57" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00160" species="s34"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00161" species="s9"/>
</listOfProducts>
<kineticLaw metaid="CDMT00162">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re57 </ci>
<ci> kmc_re57_s34 </ci>
</apply>
<ci> s34 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re57 </ci>
<ci> kmc_re57_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s34 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re57_s34 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re57_s9 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re57" id="vmaf_re57" name="Forward maximal velocity of reaction re57" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re57_s34" id="kmc_re57_s34" name="Michaelis constant of species Lymphocytes in reaction re57" value="1" units="substance"/>
<parameter metaid="vmar_re57" id="vmar_re57" name="Revere maximal velocity of reaction re57" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re57_s9" id="kmc_re57_s9" name="Michaelis constant of species IFNγ in reaction re57" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re58" id="re58" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00163" species="s9"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00164" species="s5"/>
</listOfProducts>
<kineticLaw metaid="CDMT00165">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re58 </ci>
<ci> kmc_re58_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re58 </ci>
<ci> kmc_re58_s5 </ci>
</apply>
<ci> s5 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re58_s9 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s5 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re58_s5 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re58" id="vmaf_re58" name="Forward maximal velocity of reaction re58" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re58_s9" id="kmc_re58_s9" name="Michaelis constant of species IFNγ in reaction re58" value="1" units="substance"/>
<parameter metaid="vmar_re58" id="vmar_re58" name="Revere maximal velocity of reaction re58" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re58_s5" id="kmc_re58_s5" name="Michaelis constant of species Stat-1 in reaction re58" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re59" id="re60" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00166" species="s44"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00167" species="s45"/>
</listOfProducts>
<kineticLaw metaid="CDMT00168">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re60 </ci>
<ci> kmc_re60_s44 </ci>
</apply>
<ci> s44 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re60 </ci>
<ci> kmc_re60_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s44 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re60_s44 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re60_s45 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re60" id="vmaf_re60" name="Forward maximal velocity of reaction re60" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re60_s44" id="kmc_re60_s44" name="Michaelis constant of species procaspase-8 in reaction re60" value="1" units="substance"/>
<parameter metaid="vmar_re60" id="vmar_re60" name="Revere maximal velocity of reaction re60" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re60_s45" id="kmc_re60_s45" name="Michaelis constant of species Caspase-8 in reaction re60" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re61" id="re61" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00169" species="s45"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00170" species="s25"/>
</listOfProducts>
<kineticLaw metaid="CDMT00171">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re61 </ci>
<ci> kmc_re61_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re61 </ci>
<ci> kmc_re61_s25 </ci>
</apply>
<ci> s25 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re61_s45 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re61_s25 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re61" id="vmaf_re61" name="Forward maximal velocity of reaction re61" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re61_s45" id="kmc_re61_s45" name="Michaelis constant of species Caspase-8 in reaction re61" value="1" units="substance"/>
<parameter metaid="vmar_re61" id="vmar_re61" name="Revere maximal velocity of reaction re61" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re61_s25" id="kmc_re61_s25" name="Michaelis constant of species Bcl-2 in reaction re61" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re62" id="re62" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00172" species="s45"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00173" species="s46"/>
</listOfProducts>
<kineticLaw metaid="CDMT00174">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re62 </ci>
<ci> kmc_re62_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re62 </ci>
<ci> kmc_re62_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re62_s45 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re62_s46 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re62" id="vmaf_re62" name="Forward maximal velocity of reaction re62" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re62_s45" id="kmc_re62_s45" name="Michaelis constant of species Caspase-8 in reaction re62" value="1" units="substance"/>
<parameter metaid="vmar_re62" id="vmar_re62" name="Revere maximal velocity of reaction re62" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re62_s46" id="kmc_re62_s46" name="Michaelis constant of species Cytochrome c  in reaction re62" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re63" id="re63" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00175" species="s45"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00176" species="s47"/>
</listOfProducts>
<kineticLaw metaid="CDMT00177">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re63 </ci>
<ci> kmc_re63_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re63 </ci>
<ci> kmc_re63_s47 </ci>
</apply>
<ci> s47 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re63_s45 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s47 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re63_s47 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re63" id="vmaf_re63" name="Forward maximal velocity of reaction re63" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re63_s45" id="kmc_re63_s45" name="Michaelis constant of species Caspase-8 in reaction re63" value="1" units="substance"/>
<parameter metaid="vmar_re63" id="vmar_re63" name="Revere maximal velocity of reaction re63" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re63_s47" id="kmc_re63_s47" name="Michaelis constant of species Bid in reaction re63" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re64" id="re64" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00178" species="s45"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00179" species="s48"/>
</listOfProducts>
<kineticLaw metaid="CDMT00180">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re64 </ci>
<ci> kmc_re64_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re64 </ci>
<ci> kmc_re64_s48 </ci>
</apply>
<ci> s48 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re64_s45 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re64_s48 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re64" id="vmaf_re64" name="Forward maximal velocity of reaction re64" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re64_s45" id="kmc_re64_s45" name="Michaelis constant of species Caspase-8 in reaction re64" value="1" units="substance"/>
<parameter metaid="vmar_re64" id="vmar_re64" name="Revere maximal velocity of reaction re64" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re64_s48" id="kmc_re64_s48" name="Michaelis constant of species S-nitrosylated Caspase in reaction re64" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re65" id="re65" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00181" species="s47"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00182" species="s46"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00183" species="s48"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00184">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re65 </ci>
<ci> kmc_re65_s47 </ci>
</apply>
<ci> s47 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re65 </ci>
<ci> kmc_re65_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re65_s48 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s47 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re65_s47 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re65_s46 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re65_s48 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re65" id="vmaf_re65" name="Forward maximal velocity of reaction re65" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re65_s47" id="kmc_re65_s47" name="Michaelis constant of species Bid in reaction re65" value="1" units="substance"/>
<parameter metaid="vmar_re65" id="vmar_re65" name="Revere maximal velocity of reaction re65" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re65_s46" id="kmc_re65_s46" name="Michaelis constant of species Cytochrome c  in reaction re65" value="1" units="substance"/>
<parameter metaid="kic_1_re65_s48" id="kic_1_re65_s48" name="Inhibitory constant for species S-nitrosylated Caspasewith 1 binding positions of reaction re65" value="1" units="substance"/>
<parameter metaid="kic_2_re65_s48" id="kic_2_re65_s48" name="Inhibitory constant for species S-nitrosylated Caspasewith 2 binding positions of reaction re65" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re66" id="re66" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00185" species="s25"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00186" species="s46"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00187" species="s48"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00188">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re66 </ci>
<ci> kmc_re66_s25 </ci>
</apply>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re66 </ci>
<ci> kmc_re66_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re66_s48 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re66_s25 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re66_s46 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re66_s48 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re66" id="vmaf_re66" name="Forward maximal velocity of reaction re66" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re66_s25" id="kmc_re66_s25" name="Michaelis constant of species Bcl-2 in reaction re66" value="1" units="substance"/>
<parameter metaid="vmar_re66" id="vmar_re66" name="Revere maximal velocity of reaction re66" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re66_s46" id="kmc_re66_s46" name="Michaelis constant of species Cytochrome c  in reaction re66" value="1" units="substance"/>
<parameter metaid="kic_1_re66_s48" id="kic_1_re66_s48" name="Inhibitory constant for species S-nitrosylated Caspasewith 1 binding positions of reaction re66" value="1" units="substance"/>
<parameter metaid="kic_2_re66_s48" id="kic_2_re66_s48" name="Inhibitory constant for species S-nitrosylated Caspasewith 2 binding positions of reaction re66" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re67" id="re67" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00189" species="s49"/>
<speciesReference metaid="CDMT00190" species="s51"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00191" species="s50"/>
</listOfProducts>
<kineticLaw metaid="CDMT00192">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re67 </ci>
<apply>
<times/>
<ci> kic_re67_s49 </ci>
<ci> kmc_re67_s51 </ci>
</apply>
</apply>
<ci> s49 </ci>
<ci> default </ci>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re67 </ci>
<ci> kmc_re67_s50 </ci>
</apply>
<ci> s50 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s50 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re67_s50 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s49 </ci>
<ci> default </ci>
</apply>
<ci> kic_re67_s49 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s49 </ci>
<ci> default </ci>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<ci> kic_re67_s49 </ci>
<ci> kmc_re67_s51 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<ci> kic_re67_s51 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re67" id="vmaf_re67" name="Forward maximal velocity of reaction re67" value="1" units="mole_per_second"/>
<parameter metaid="vmar_re67" id="vmar_re67" name="Revere maximal velocity of reaction re67" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re67_s51" id="kmc_re67_s51" name="Michaelis constant of species ICE in reaction re67" value="1" units="substance"/>
<parameter metaid="kmc_re67_s50" id="kmc_re67_s50" name="Michaelis constant of species Mature IL-1β in reaction re67" value="1" units="substance"/>
<parameter metaid="kic_re67_s49" id="kic_re67_s49" name="Inhibitory constant for species pro-IL-1β of reaction re67" value="1" units="substance"/>
<parameter metaid="kic_re67_s51" id="kic_re67_s51" name="Inhibitory constant for species ICE of reaction re67" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re68" id="re68" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00193" species="s50"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00194" species="s11"/>
</listOfProducts>
<kineticLaw metaid="CDMT00195">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re68 </ci>
<ci> kmc_re68_s50 </ci>
</apply>
<ci> s50 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re68 </ci>
<ci> kmc_re68_s11 </ci>
</apply>
<ci> s11 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s50 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re68_s50 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s11 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re68_s11 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re68" id="vmaf_re68" name="Forward maximal velocity of reaction re68" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re68_s50" id="kmc_re68_s50" name="Michaelis constant of species Mature IL-1β in reaction re68" value="1" units="substance"/>
<parameter metaid="vmar_re68" id="vmar_re68" name="Revere maximal velocity of reaction re68" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re68_s11" id="kmc_re68_s11" name="Michaelis constant of species IL-1β in reaction re68" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re69" id="re69" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00196" species="s52"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00197" species="s51"/>
</listOfProducts>
<kineticLaw metaid="CDMT00198">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re69 </ci>
<ci> kmc_re69_s52 </ci>
</apply>
<ci> s52 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re69 </ci>
<ci> kmc_re69_s51 </ci>
</apply>
<ci> s51 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s52 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re69_s52 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re69_s51 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re69" id="vmaf_re69" name="Forward maximal velocity of reaction re69" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re69_s52" id="kmc_re69_s52" name="Michaelis constant of species Caspase-1 in reaction re69" value="1" units="substance"/>
<parameter metaid="vmar_re69" id="vmar_re69" name="Revere maximal velocity of reaction re69" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re69_s51" id="kmc_re69_s51" name="Michaelis constant of species ICE in reaction re69" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re70" id="re70" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00199" species="s53"/>
<speciesReference metaid="CDMT00200" species="s51"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00201" species="s9"/>
</listOfProducts>
<kineticLaw metaid="CDMT00202">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re70 </ci>
<apply>
<times/>
<ci> kic_re70_s53 </ci>
<ci> kmc_re70_s51 </ci>
</apply>
</apply>
<ci> s53 </ci>
<ci> default </ci>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re70 </ci>
<ci> kmc_re70_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re70_s9 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s53 </ci>
<ci> default </ci>
</apply>
<ci> kic_re70_s53 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s53 </ci>
<ci> default </ci>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<ci> kic_re70_s53 </ci>
<ci> kmc_re70_s51 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s51 </ci>
<ci> default </ci>
</apply>
<ci> kic_re70_s51 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re70" id="vmaf_re70" name="Forward maximal velocity of reaction re70" value="1" units="mole_per_second"/>
<parameter metaid="vmar_re70" id="vmar_re70" name="Revere maximal velocity of reaction re70" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re70_s51" id="kmc_re70_s51" name="Michaelis constant of species ICE in reaction re70" value="1" units="substance"/>
<parameter metaid="kmc_re70_s9" id="kmc_re70_s9" name="Michaelis constant of species IFNγ in reaction re70" value="1" units="substance"/>
<parameter metaid="kic_re70_s53" id="kic_re70_s53" name="Inhibitory constant for species IL-18 of reaction re70" value="1" units="substance"/>
<parameter metaid="kic_re70_s51" id="kic_re70_s51" name="Inhibitory constant for species ICE of reaction re70" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re72" id="re72" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00203" species="s9"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00204" species="s9"/>
</listOfProducts>
<kineticLaw metaid="CDMT00205">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re72 </ci>
<ci> kmc_re72_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re72 </ci>
<ci> kmc_re72_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re72_s9 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re72_s9 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re72" id="vmaf_re72" name="Forward maximal velocity of reaction re72" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re72_s9" id="kmc_re72_s9" name="Michaelis constant of species IFNγ in reaction re72" value="1" units="substance"/>
<parameter metaid="vmar_re72" id="vmar_re72" name="Revere maximal velocity of reaction re72" value="1" units="mole_per_second"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re73" id="re73" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00206" species="s52"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00207" species="s48"/>
</listOfProducts>
<kineticLaw metaid="CDMT00208">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re73 </ci>
<ci> kmc_re73_s52 </ci>
</apply>
<ci> s52 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re73 </ci>
<ci> kmc_re73_s48 </ci>
</apply>
<ci> s48 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s52 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re73_s52 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s48 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re73_s48 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re73" id="vmaf_re73" name="Forward maximal velocity of reaction re73" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re73_s52" id="kmc_re73_s52" name="Michaelis constant of species Caspase-1 in reaction re73" value="1" units="substance"/>
<parameter metaid="vmar_re73" id="vmar_re73" name="Revere maximal velocity of reaction re73" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re73_s48" id="kmc_re73_s48" name="Michaelis constant of species S-nitrosylated Caspase in reaction re73" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re74" id="re74" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00209" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00210" species="s54"/>
</listOfProducts>
<kineticLaw metaid="CDMT00211">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re74 </ci>
<ci> kmc_re74_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re74 </ci>
<ci> kmc_re74_s54 </ci>
</apply>
<ci> s54 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re74_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s54 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re74_s54 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re74" id="vmaf_re74" name="Forward maximal velocity of reaction re74" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re74_s1" id="kmc_re74_s1" name="Michaelis constant of species NO in reaction re74" value="1" units="substance"/>
<parameter metaid="vmar_re74" id="vmar_re74" name="Revere maximal velocity of reaction re74" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re74_s54" id="kmc_re74_s54" name="Michaelis constant of species P53 in reaction re74" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re75" id="re75" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00212" species="s54"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00213" species="s55"/>
</listOfProducts>
<kineticLaw metaid="CDMT00214">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re75 </ci>
<ci> kmc_re75_s54 </ci>
</apply>
<ci> s54 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re75 </ci>
<ci> kmc_re75_s55 </ci>
</apply>
<ci> s55 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s54 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re75_s54 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s55 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re75_s55 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re75" id="vmaf_re75" name="Forward maximal velocity of reaction re75" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re75_s54" id="kmc_re75_s54" name="Michaelis constant of species P53 in reaction re75" value="1" units="substance"/>
<parameter metaid="vmar_re75" id="vmar_re75" name="Revere maximal velocity of reaction re75" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re75_s55" id="kmc_re75_s55" name="Michaelis constant of species Bax in reaction re75" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re76" id="re76" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00215" species="s55"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00216" species="s46"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid="CDMT00217" species="s25"/>
</listOfModifiers>
<kineticLaw metaid="CDMT00218">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re76 </ci>
<ci> kmc_re76_s55 </ci>
</apply>
<ci> s55 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re76 </ci>
<ci> kmc_re76_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<ci> kic_1_re76_s25 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci> s55 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re76_s55 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re76_s46 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s25 </ci>
<ci> default </ci>
</apply>
<ci> kic_2_re76_s25 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re76" id="vmaf_re76" name="Forward maximal velocity of reaction re76" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re76_s55" id="kmc_re76_s55" name="Michaelis constant of species Bax in reaction re76" value="1" units="substance"/>
<parameter metaid="vmar_re76" id="vmar_re76" name="Revere maximal velocity of reaction re76" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re76_s46" id="kmc_re76_s46" name="Michaelis constant of species Cytochrome c  in reaction re76" value="1" units="substance"/>
<parameter metaid="kic_1_re76_s25" id="kic_1_re76_s25" name="Inhibitory constant for species Bcl-2with 1 binding positions of reaction re76" value="1" units="substance"/>
<parameter metaid="kic_2_re76_s25" id="kic_2_re76_s25" name="Inhibitory constant for species Bcl-2with 2 binding positions of reaction re76" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re77" id="re77" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00219" species="s46"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00220" species="s56"/>
</listOfProducts>
<kineticLaw metaid="CDMT00221">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re77 </ci>
<ci> kmc_re77_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re77 </ci>
<ci> kmc_re77_s56 </ci>
</apply>
<ci> s56 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re77_s46 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re77_s56 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re77" id="vmaf_re77" name="Forward maximal velocity of reaction re77" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re77_s46" id="kmc_re77_s46" name="Michaelis constant of species Cytochrome c  in reaction re77" value="1" units="substance"/>
<parameter metaid="vmar_re77" id="vmar_re77" name="Revere maximal velocity of reaction re77" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re77_s56" id="kmc_re77_s56" name="Michaelis constant of species Caspase-3 in reaction re77" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re78" id="re78" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00222" species="s57"/>
<speciesReference metaid="CDMT00223" species="s59"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00224" species="s58"/>
</listOfProducts>
<kineticLaw metaid="CDMT00225">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re78 </ci>
<apply>
<times/>
<ci> kic_re78_s57 </ci>
<ci> kmc_re78_s59 </ci>
</apply>
</apply>
<ci> s57 </ci>
<ci> default </ci>
<ci> s59 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re78 </ci>
<ci> kmc_re78_s58 </ci>
</apply>
<ci> s58 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re78_s58 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s57 </ci>
<ci> default </ci>
</apply>
<ci> kic_re78_s57 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s57 </ci>
<ci> default </ci>
<ci> s59 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<ci> kic_re78_s57 </ci>
<ci> kmc_re78_s59 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s59 </ci>
<ci> default </ci>
</apply>
<ci> kic_re78_s59 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re78" id="vmaf_re78" name="Forward maximal velocity of reaction re78" value="1" units="mole_per_second"/>
<parameter metaid="vmar_re78" id="vmar_re78" name="Revere maximal velocity of reaction re78" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re78_s59" id="kmc_re78_s59" name="Michaelis constant of species Apaf1 in reaction re78" value="1" units="substance"/>
<parameter metaid="kmc_re78_s58" id="kmc_re78_s58" name="Michaelis constant of species Caspase-9 in reaction re78" value="1" units="substance"/>
<parameter metaid="kic_re78_s57" id="kic_re78_s57" name="Inhibitory constant for species procaspase-9 of reaction re78" value="1" units="substance"/>
<parameter metaid="kic_re78_s59" id="kic_re78_s59" name="Inhibitory constant for species Apaf1 of reaction re78" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re79" id="re79" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00226" species="s58"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00227" species="s56"/>
</listOfProducts>
<kineticLaw metaid="CDMT00228">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re79 </ci>
<ci> kmc_re79_s58 </ci>
</apply>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re79 </ci>
<ci> kmc_re79_s56 </ci>
</apply>
<ci> s56 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re79_s58 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re79_s56 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re79" id="vmaf_re79" name="Forward maximal velocity of reaction re79" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re79_s58" id="kmc_re79_s58" name="Michaelis constant of species Caspase-9 in reaction re79" value="1" units="substance"/>
<parameter metaid="vmar_re79" id="vmar_re79" name="Revere maximal velocity of reaction re79" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re79_s56" id="kmc_re79_s56" name="Michaelis constant of species Caspase-3 in reaction re79" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re80" id="re80" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00229" species="s58"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00230" species="s60"/>
</listOfProducts>
<kineticLaw metaid="CDMT00231">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re80 </ci>
<ci> kmc_re80_s58 </ci>
</apply>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re80 </ci>
<ci> kmc_re80_s60 </ci>
</apply>
<ci> s60 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re80_s58 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s60 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re80_s60 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re80" id="vmaf_re80" name="Forward maximal velocity of reaction re80" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re80_s58" id="kmc_re80_s58" name="Michaelis constant of species Caspase-9 in reaction re80" value="1" units="substance"/>
<parameter metaid="vmar_re80" id="vmar_re80" name="Revere maximal velocity of reaction re80" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re80_s60" id="kmc_re80_s60" name="Michaelis constant of species Caspase 7 in reaction re80" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re81" id="re81" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00232" species="s45"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00233" species="s56"/>
</listOfProducts>
<kineticLaw metaid="CDMT00234">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re81 </ci>
<ci> kmc_re81_s45 </ci>
</apply>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re81 </ci>
<ci> kmc_re81_s56 </ci>
</apply>
<ci> s56 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s45 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re81_s45 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re81_s56 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re81" id="vmaf_re81" name="Forward maximal velocity of reaction re81" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re81_s45" id="kmc_re81_s45" name="Michaelis constant of species Caspase-8 in reaction re81" value="1" units="substance"/>
<parameter metaid="vmar_re81" id="vmar_re81" name="Revere maximal velocity of reaction re81" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re81_s56" id="kmc_re81_s56" name="Michaelis constant of species Caspase-3 in reaction re81" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re82" id="re82" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00235" species="s56"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00236" species="s61"/>
</listOfProducts>
<kineticLaw metaid="CDMT00237">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re82 </ci>
<ci> kmc_re82_s56 </ci>
</apply>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re82 </ci>
<ci> kmc_re82_s61 </ci>
</apply>
<ci> s61 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re82_s56 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s61 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re82_s61 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re82" id="vmaf_re82" name="Forward maximal velocity of reaction re82" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re82_s56" id="kmc_re82_s56" name="Michaelis constant of species Caspase-3 in reaction re82" value="1" units="substance"/>
<parameter metaid="vmar_re82" id="vmar_re82" name="Revere maximal velocity of reaction re82" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re82_s61" id="kmc_re82_s61" name="Michaelis constant of species Apoptosis in reaction re82" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re83" id="re83" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00238" species="s1"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00239" species="s62"/>
</listOfProducts>
<kineticLaw metaid="CDMT00240">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re83 </ci>
<ci> kmc_re83_s1 </ci>
</apply>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re83 </ci>
<ci> kmc_re83_s62 </ci>
</apply>
<ci> s62 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s1 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re83_s1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s62 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re83_s62 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re83" id="vmaf_re83" name="Forward maximal velocity of reaction re83" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re83_s1" id="kmc_re83_s1" name="Michaelis constant of species NO in reaction re83" value="1" units="substance"/>
<parameter metaid="vmar_re83" id="vmar_re83" name="Revere maximal velocity of reaction re83" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re83_s62" id="kmc_re83_s62" name="Michaelis constant of species T cell in reaction re83" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re84" id="re84" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00241" species="s46"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00242" species="s58"/>
</listOfProducts>
<kineticLaw metaid="CDMT00243">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re84 </ci>
<ci> kmc_re84_s46 </ci>
</apply>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re84 </ci>
<ci> kmc_re84_s58 </ci>
</apply>
<ci> s58 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s46 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re84_s46 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s58 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re84_s58 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re84" id="vmaf_re84" name="Forward maximal velocity of reaction re84" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re84_s46" id="kmc_re84_s46" name="Michaelis constant of species Cytochrome c  in reaction re84" value="1" units="substance"/>
<parameter metaid="vmar_re84" id="vmar_re84" name="Revere maximal velocity of reaction re84" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re84_s58" id="kmc_re84_s58" name="Michaelis constant of species Caspase-9 in reaction re84" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re85" id="re85" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00244" species="s39"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00245" species="s63"/>
</listOfProducts>
<kineticLaw metaid="CDMT00246">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re85 </ci>
<ci> kmc_re85_s39 </ci>
</apply>
<ci> s39 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re85 </ci>
<ci> kmc_re85_s63 </ci>
</apply>
<ci> s63 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s39 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re85_s39 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re85_s63 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re85" id="vmaf_re85" name="Forward maximal velocity of reaction re85" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re85_s39" id="kmc_re85_s39" name="Michaelis constant of species Viral infection in reaction re85" value="1" units="substance"/>
<parameter metaid="vmar_re85" id="vmar_re85" name="Revere maximal velocity of reaction re85" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re85_s63" id="kmc_re85_s63" name="Michaelis constant of species PRRs in reaction re85" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re86" id="re86" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00247" species="s63"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00248" species="s64"/>
</listOfProducts>
<kineticLaw metaid="CDMT00249">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re86 </ci>
<ci> kmc_re86_s63 </ci>
</apply>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re86 </ci>
<ci> kmc_re86_s64 </ci>
</apply>
<ci> s64 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re86_s63 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s64 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re86_s64 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re86" id="vmaf_re86" name="Forward maximal velocity of reaction re86" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re86_s63" id="kmc_re86_s63" name="Michaelis constant of species PRRs in reaction re86" value="1" units="substance"/>
<parameter metaid="vmar_re86" id="vmar_re86" name="Revere maximal velocity of reaction re86" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re86_s64" id="kmc_re86_s64" name="Michaelis constant of species IRF-3 in reaction re86" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re87" id="re87" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00250" species="s63"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00251" species="s65"/>
</listOfProducts>
<kineticLaw metaid="CDMT00252">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re87 </ci>
<ci> kmc_re87_s63 </ci>
</apply>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re87 </ci>
<ci> kmc_re87_s65 </ci>
</apply>
<ci> s65 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re87_s63 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s65 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re87_s65 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re87" id="vmaf_re87" name="Forward maximal velocity of reaction re87" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re87_s63" id="kmc_re87_s63" name="Michaelis constant of species PRRs in reaction re87" value="1" units="substance"/>
<parameter metaid="vmar_re87" id="vmar_re87" name="Revere maximal velocity of reaction re87" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re87_s65" id="kmc_re87_s65" name="Michaelis constant of species IRF-7 in reaction re87" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re88" id="re88" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00253" species="s63"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00254" species="s15"/>
</listOfProducts>
<kineticLaw metaid="CDMT00255">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re88 </ci>
<ci> kmc_re88_s63 </ci>
</apply>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re88 </ci>
<ci> kmc_re88_s15 </ci>
</apply>
<ci> s15 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s63 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re88_s63 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re88_s15 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re88" id="vmaf_re88" name="Forward maximal velocity of reaction re88" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re88_s63" id="kmc_re88_s63" name="Michaelis constant of species PRRs in reaction re88" value="1" units="substance"/>
<parameter metaid="vmar_re88" id="vmar_re88" name="Revere maximal velocity of reaction re88" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re88_s15" id="kmc_re88_s15" name="Michaelis constant of species IRF-1 in reaction re88" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re89" id="re89" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00256" species="s15"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00257" species="s13"/>
</listOfProducts>
<kineticLaw metaid="CDMT00258">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re89 </ci>
<ci> kmc_re89_s15 </ci>
</apply>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re89 </ci>
<ci> kmc_re89_s13 </ci>
</apply>
<ci> s13 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re89_s15 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s13 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re89_s13 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re89" id="vmaf_re89" name="Forward maximal velocity of reaction re89" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re89_s15" id="kmc_re89_s15" name="Michaelis constant of species IRF-1 in reaction re89" value="1" units="substance"/>
<parameter metaid="vmar_re89" id="vmar_re89" name="Revere maximal velocity of reaction re89" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re89_s13" id="kmc_re89_s13" name="Michaelis constant of species IL-12 in reaction re89" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re90" id="re90" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00259" species="s15"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00260" species="s9"/>
</listOfProducts>
<kineticLaw metaid="CDMT00261">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re90 </ci>
<ci> kmc_re90_s15 </ci>
</apply>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re90 </ci>
<ci> kmc_re90_s9 </ci>
</apply>
<ci> s9 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s15 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re90_s15 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s9 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re90_s9 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re90" id="vmaf_re90" name="Forward maximal velocity of reaction re90" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re90_s15" id="kmc_re90_s15" name="Michaelis constant of species IRF-1 in reaction re90" value="1" units="substance"/>
<parameter metaid="vmar_re90" id="vmar_re90" name="Revere maximal velocity of reaction re90" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re90_s9" id="kmc_re90_s9" name="Michaelis constant of species IFNγ in reaction re90" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction metaid="re91" id="re91" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00262" species="s60"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00263" species="s56"/>
</listOfProducts>
<kineticLaw metaid="CDMT00264">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<ci> vmaf_re91 </ci>
<ci> kmc_re91_s60 </ci>
</apply>
<ci> s60 </ci>
<ci> default </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> vmar_re91 </ci>
<ci> kmc_re91_s56 </ci>
</apply>
<ci> s56 </ci>
<ci> default </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> s60 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re91_s60 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> s56 </ci>
<ci> default </ci>
</apply>
<ci> kmc_re91_s56 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter metaid="vmaf_re91" id="vmaf_re91" name="Forward maximal velocity of reaction re91" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re91_s60" id="kmc_re91_s60" name="Michaelis constant of species Caspase 7 in reaction re91" value="1" units="substance"/>
<parameter metaid="vmar_re91" id="vmar_re91" name="Revere maximal velocity of reaction re91" value="1" units="mole_per_second"/>
<parameter metaid="kmc_re91_s56" id="kmc_re91_s56" name="Michaelis constant of species Caspase-3 in reaction re91" value="1" units="substance"/>
</listOfParameters>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>