//Adapted as is from L5 PFC microcircuit used to study persistent activity (Papoutsi et al.2014,2013)
//Accession: 155057
begintemplate INcell
public soma, axon
create soma, axon
proc init () {
create soma, axon
soma {
nseg=1
L=53
diam=42
insert pas
cm=1.2
g_pas =1/15000
e_pas = -70
Ra=150
insert Naf_in
gnafbar_Naf_in= 0.045*5
insert kdr_in
gkdrbar_kdr_in=0.018
insert IKs_in
gKsbar_IKs_in = 0.000725*0.1
}
axon {
nseg=1
L=113.22
diam=0.7
insert pas
cm=1.2
g_pas =1/15000
e_pas = -70
Ra=150
insert Naf_in
gnafbar_Naf_in=0.045*12
insert kdr_in
gkdrbar_kdr_in=0.018
}
connect axon(0), soma(0.5)
ko0_k_ion = 3.82
ki0_k_ion = 140
celsius = 34
}
init()
endtemplate INcell
//Create interneurons
nINcells = 1
objref INcells[nINcells]
for i = 0, nINcells-1 {
INcells[i] = new INcell()
}
//Create list with sections
objref insoma_list
insoma_list = new SectionList()
for i=0, nINcells-1 {
INcells[i].soma insoma_list.append()
}
proc current_balancein() {
finitialize($1)
fcurrent()
forsec insoma_list {
for (x) {
if (ismembrane("na_ion") && ismembrane("ca_ion") && (ismembrane("k_ion"))){
e_pas(x)=(ina(x)+ik(x)+ica(x)+g_pas(x)*v(x))/g_pas(x)
} else if (ismembrane("na_ion") && (ismembrane("k_ion"))) {
e_pas(x)=(ina(x)+ik(x)+g_pas(x)*v(x))/g_pas(x)
} else {
e_pas(x)=v(x)
}
fcurrent()
}
}
}
current_balancein(-70)