: Author: David Catherall
: Created: November 2016
: Extracellular potassium ion accumulation
: Adapted from Hines and Carnevale 2000: Guide to NMODL
: Upon further inspection, this doesn't appear in Schild 1994. Saving for furture use if needed.
NEURON {
SUFFIX kext
USEION k READ ik WRITE ko
GLOBAL kbath
RANGE fhspace, txfer
}
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
FARADAY = (faraday) (coulombs)
(molar) = (1/liter)
(mM) = (millimolar)
}
PARAMETER {
kbath = 5.4 (mM) : seawater (squid axon!)
fhspace = 1e-4 (cm) :Thickness of Shell
txfer = 50 (ms) : tau for F-H space <-> bath exchange = 30-100
}
ASSIGNED { ik (mA/cm2) }
STATE { ko (mM) }
BREAKPOINT { SOLVE state METHOD cnexp }
DERIVATIVE state {
ko' = ik/(fhspace*FARADAY) + (kbath - ko)/txfer
}