MAIN FILE: Spiny.g Script files: Script_*.g Input files: Ca input: InpCaAlpsxxx.txt DA input: InpDAAlpxxx.txt where xxx is a amplitude of the input. To reproduce figures in the paper, please run script files as below. .g files are the file format of GENESIS/kinetikit .cps files are the file format of COPASI Fig5 Script_ctr_Ca010.g Script_ctr_Ca100.g Script_ctr_DA.g Fig6 Script_ctr_Ca010.g Script_ctr_Ca.g Script_DA000_DA_Ca010.g Fig7 many... Script_ctr_Ca???.g Script_PP1fix_Ca???.g Script_PKAfix_Ca???.g Script_CaMKIIfix_Ca???.g Fig8 Script_ctr_Ca.g Script_CDK5CK1_Ca.g Fig9 Script_ctr_Ca.g Script_ctr_DA.g Script_DKO_Ca.g Script_DKO_DA.g Fig10 Script_ctr_Ca010.g Script_ctr_Ca.g Script_DKO_Ca010.g Script_DKO_Ca.g Script_ctr_Ca???.g Script_DKO_Ca???.g Fig11 Loop4_analysis.cps Fig12 Loop4_analysis.cps Fig13 Script_Loop_InhPKA_Kd*.g Script_Loop_PKAPP2A_Kcat*.g Script_Loop_PP2AD75_Kcat*.g Fig14 Script_DA020_DA_Ca010.g Script_DA020_Ca.g Script_DA020_Ca010.g Fig. S1 Script_ctr_Ca100_timedn500.g Script_ctr_Ca100_timedp500.g Script_ctr_Ca010_timedn100.g Script_ctr_Ca010_timedp050.g Script_ctr_Ca010_timedn050.g Script_ctr_Ca010_timedp100.g Script_ctr_Ca010_timedn500.g Script_ctr_Ca010_timedp500.g Fig. S2 Script_long_Ca.g Script_long_Ca010.g