: Rod Photoreceptor Kv channel
:modified 2004-02-05 in obersavation of mixed up of Kx and Kv in Kamiyama's 1996 paper
:based on HH 1952 paper and Koch book
NEURON
{
SUFFIX Kv
USEION Kv WRITE iKv VALENCE 1
RANGE gKvbar, eKv
}
UNITS
{
(mA) = (milliamp)
(mV) = (millivolt)
(mS) = (millimho)
}
PARAMETER
{
: potassium delayed rectifier (originally was 2 mS/cm2, -80 mV)
gKvbar = 10 (mS/cm2) <0,1e9> :was 1
eKv = -80 (mV) :was -74mV
}
STATE
{
mKv
}
ASSIGNED
{
v (mV)
iKv (mA/cm2)
: potassium delayed rectifier, K
infmKv
taumKv (ms)
gKv (mho/cm2)
}
INITIAL
{
rate(v)
mKv = infmKv
}
BREAKPOINT
{
SOLVE states METHOD cnexp
gKv = (0.001)*gKvbar*mKv*mKv*mKv*mKv
iKv = gKv*(v - eKv)
}
DERIVATIVE states
{
rate(v)
mKv' = (infmKv - mKv)/taumKv
}
UNITSOFF
FUNCTION alphamKv(v(mV)) (/ms)
{
alphamKv = 0.005*(20-v)/( exp( (20-v)/22) -1 )
:modified from 10
}
FUNCTION betamKv (v(mV)) (/ms)
{
betamKv = 1/16*exp (- v/80 )
}
UNITSON
PROCEDURE rate(v (mV))
{
LOCAL am, bm
am = alphamKv(v)
bm = betamKv(v)
taumKv = 1/(am + bm)
infmKv = am*taumKv
}