// Morphology file for Purkinje cell
// (c) Erik De Schutter, Caltech 1991-1992
// Original data provided by Rapp, Yarom and Segev, Hebrew University Jerusalem
// Active membrane model with 1 spine on every spiny compartment
// References: Rapp, M., Segev, I., and Yarom, Y. (1994) Physiology,
// morphology and detailed passive models of cerebellar Purkinje cells.
// J. Physiol. (London), 471: 87-99.
// De Schutter, E. and Bower, J. M. (1994) An active membrane
// model of the cerebellar Purkinje cell: I. Simulation of current
// clamps in slice. J. Neurophysiol., 71: 375-400.
// http://www.bbf.uia.ac.be/TNB/TNB_pub8.html
// De Schutter, E. and Bower, J. M. (1994) An active membrane
// model of the cerebellar Purkinje cell: II. Simulation of synaptic
// responses. J. Neurophysiol., 71: 401-419.
// http://www.bbf.uia.ac.be/TNB/TNB_pub7.html
*relative
*set_compt_param RM {RMs}
*set_compt_param RA {RA}
*set_compt_param CM {CM}
*set_compt_param ELEAK {ELEAK}
*set_compt_param EREST_ACT {EREST_ACT}
*compt /library/Purk_soma
soma none 0.000 0.000 0.000 29.80
*set_compt_param RM {RMd}
// add one spine per compartment with dia <= 3.17 um and
// expand membrane for missing spines
*rand_spines 3.17 13 1.33 7.54 1.00 /library/Purk_spine
*compt /library/Purk_maind
main[0] soma 5.557 9.447 9.447 7.72
main[1] main[0] 8.426 1.124 21.909 8.22
main[2] main[1] 1.666 1.111 6.666 8.50
main[3] main[2] -2.779 2.223 1.667 9.22
main[4] main[3] -1.111 6.109 5.553 8.89
main[5] main[4] -1.111 -0.555 4.998 8.44
main[6] main[5] -1.749 0.583 3.498 8.61
main[7] main[6] -3.890 3.334 6.669 7.78
main[8] main[7] -6.665 -1.111 9.441 8.44
*compt /library/Purk_thickd
br1[0] main[8] -4.443 1.111 0.000 7.94
br1[1] . -4.440 -0.555 1.110 5.39
br1[2] . -13.334 0.000 1.111 5.06
br1[3] . -3.330 0.555 2.775 4.83
br1[4] . -6.114 3.335 5.558 4.22
br1[5] . -8.330 1.111 3.332 4.22
br1[6] . -3.888 0.000 5.554 4.00
br1[7] . -4.444 0.000 2.777 5.00
br1[8] . -1.666 -2.777 5.555 6.06
br1[9] . 0.000 3.888 7.220 5.17
br1[10] . -1.110 1.665 4.440 4.44
br1[11] . -6.668 0.000 13.336 4.33
br1[12] . -3.889 0.000 13.334 5.00
br1[13] . 1.113 1.113 3.338 5.78
br1[14] . 0.000 0.000 2.220 5.44
br1[15] . -0.556 0.556 13.888 4.33
br1[16] . 0.555 -0.555 3.329 3.56
br1[17] . 2.222 -0.556 8.890 3.83
br1[18] . -0.555 1.666 7.219 4.17
br1[19] . -1.110 0.000 3.885 4.78
br1[20] . -6.111 -1.667 1.667 4.17
*compt /library/Purk_thickd
b0s01[0] main[1] 6.110 0.555 -0.555 5.28
*compt /library/Purk_spinyd
b0s01[1] b0s01[0] 2.220 0.000 0.000 2.28
b0s01[2] . 3.892 -1.668 -3.336 1.83
b0s01[3] . 1.151 0.000 -10.356 1.44
b0s01[4] . -1.667 0.000 -2.778 1.44
b0s01[5] . -2.432 0.000 -1.824 1.44
b0s01[6] . -9.438 1.180 0.590 1.44
b0s01[7] b0s01[5] 0.907 0.907 -3.630 1.44
b0s01[8] . -2.778 0.000 -1.667 1.44
b0s01[9] b0s01[7] 0.000 0.000 -4.050 1.44
b0s01[10] . -16.009 0.000 -9.606 1.44
b0s01[11] b0s01[9] 0.000 -1.109 -1.664 1.28
b0s01[12] . -2.226 0.556 -1.113 1.11
b0s01[13] . -1.109 0.000 1.664 1.00
b0s01[14] b0s01[12] -3.336 0.556 -1.112 1.00
b0s01[15] . -0.555 0.000 -1.109 0.89
b0s01[16] . -8.055 -1.151 -8.055 0.89
b0s01[17] b0s01[15] 3.890 0.000 0.000 0.89
b0s01[18] . 2.218 0.000 -1.109 0.94
b0s01[19] . 0.680 0.000 -4.762 1.00
b0s01[20] b0s01[11] 1.664 0.000 -1.109 1.06
b0s01[21] . 1.112 0.556 -3.336 1.11
b0s01[22] . 1.111 0.000 -8.336 1.22
b0s01[23] b0s01[4] -1.664 0.000 1.109 1.33
b0s01[24] . -3.334 0.000 0.556 1.22
b0s01[25] . -2.780 0.000 0.000 1.06
b0s01[26] . 0.000 0.000 -1.670 0.83
b0s01[27] . -3.888 0.000 -1.666 0.78
b0s01[28] b0s01[25] -2.220 0.000 0.000 0.83
b0s01[29] . -3.887 0.000 -3.332 0.83
b0s01[30] . -2.777 0.000 -4.444 0.83
b0s01[31] b0s01[3] 1.109 0.000 -1.664 1.22
b0s01[32] . 6.271 0.000 -6.841 1.00
b0s01[33] . -6.155 -0.560 -22.382 1.00
b0s01[34] b0s01[32] 4.443 -1.111 0.000 1.00
b0s01[35] . 3.336 0.000 -1.668 1.11
b0s01[36] . 2.776 1.110 -2.776 1.28
b0s01[37] . 2.224 0.000 -3.337 1.50
b0s01[38] . 4.443 -0.555 -4.998 1.67
b0s01[39] b0s01[31] 2.778 0.000 -1.667 1.17
b0s01[40] . 2.775 0.000 -0.555 1.33
b0s01[41] . 4.999 0.000 -2.222 1.22
b0s01[42] . 4.445 0.000 -0.556 1.06
b0s01[43] . 1.669 0.000 -1.669 1.00
b0s01[44] . 2.224 0.000 -2.780 1.22
*compt /library/Purk_thickd
b1s14[0] br1[14] 3.329 0.555 0.555 3.61
*compt /library/Purk_spinyd
b1s14[1] b1s14[0] 3.336 0.556 3.336 2.56
b1s14[2] . 3.885 -1.110 -1.665 2.50
b1s14[3] . 8.511 0.000 1.702 2.00
b1s14[4] . 2.223 0.000 4.445 2.11
b1s14[5] . 2.221 0.000 5.552 2.11
b1s14[6] . 2.778 0.000 3.334 2.00
b1s14[7] . 1.667 0.000 5.000 2.89
b1s14[8] . 4.440 0.000 0.000 2.83
b1s14[9] . 2.777 0.000 4.444 1.72
b1s14[10] . 5.028 0.000 12.291 1.56
b1s14[11] . -1.111 0.555 5.553 1.50
b1s14[12] . 2.222 0.556 5.556 1.44
b1s14[13] b1s14[10] 3.886 0.000 4.997 1.39
b1s14[14] . 1.668 0.000 4.448 1.22
b1s14[15] . 3.334 1.667 1.111 1.33
b1s14[16] b1s14[7] 3.889 0.000 3.889 2.61
b1s14[17] b1s14[1] 0.000 -0.556 6.115 2.56
b1s14[18] . 1.111 -0.555 5.553 2.28
b1s14[19] . 8.394 0.000 16.788 2.44
b1s14[20] . 3.329 0.555 0.555 2.22
b1s14[21] . 5.041 0.000 6.931 2.00
b1s14[22] . 1.110 1.666 7.218 1.61
b1s14[23] . 0.555 -1.665 2.220 1.22
b1s14[24] b1s14[19] 0.000 0.000 6.110 2.06
b1s14[25] . -1.666 0.000 3.888 1.67
b1s14[26] . -4.447 2.223 4.447 1.78
b1s14[27] . -1.111 0.000 8.891 2.00
b1s14[28] . -9.477 0.000 6.690 2.11
b1s14[29] . 2.234 -1.117 10.054 2.11
b1s14[30] . -1.111 0.000 9.998 1.89
b1s14[31] . -6.668 0.000 5.557 1.50
b1s14[32] b1s14[30] 3.334 0.000 5.001 1.50
b1s14[33] . -2.221 0.000 5.552 1.33
b1s14[34] b1s14[29] 5.557 0.000 6.668 1.72
b1s14[35] . 1.146 0.573 15.477 1.33
b1s14[36] b1s14[28] -5.556 1.111 2.778 1.89
b1s14[37] . -3.336 -0.556 3.336 1.67
b1s14[38] . 1.667 1.111 10.001 1.72
b1s14[39] . 6.664 -0.555 8.885 1.61
b1s14[40] b1s14[27] 2.781 -0.556 1.668 1.72
b1s14[41] . 6.244 0.568 15.327 1.33
b1s14[42] . 5.000 0.000 4.445 1.67
*compt /library/Purk_spinyd
b1s15[0] br1[16] -2.777 1.111 1.111 2.61
b1s15[1] . -10.034 0.000 10.592 1.67
b1s15[2] b1s15[0] -2.220 0.000 0.000 1.44
b1s15[3] . -4.444 0.000 2.777 1.22
b1s15[4] . -3.890 0.000 2.223 1.11
b1s15[5] b1s15[2] -5.001 0.000 -3.334 1.11
b1s15[6] . -9.267 -0.579 2.317 1.00
b1s15[7] b1s15[5] -10.014 0.626 -3.129 1.00
*compt /library/Purk_thickd
b1s16[0] br1[17] -6.112 0.556 1.667 3.28
*compt /library/Purk_spinyd
b1s16[1] b1s16[0] -3.336 0.000 4.448 2.44
b1s16[2] . -4.445 0.000 2.223 2.06
*compt /library/Purk_spinyd
b1s17[0] br1[18] 7.220 0.000 -1.666 2.94
b1s17[1] . 8.331 0.555 -3.332 1.50
*compt /library/Purk_spinyd
b1s18[0] br1[19] -0.556 0.000 -3.334 3.11
*compt /library/Purk_spinyd
b1s19[0] br1[20] -0.556 0.000 -3.334 2.56
b1s19[1] . 0.000 0.555 -4.999 1.83
b1s19[2] . -0.556 0.000 -3.334 1.39
b1s19[3] b1s19[0] -4.446 -0.556 6.114 2.72
b1s19[4] . -6.107 0.555 -3.886 2.78
b1s19[5] . -9.442 -0.555 -4.443 2.17
b1s19[6] . -4.440 0.000 0.000 2.11
b1s19[7] . -3.337 0.000 -2.224 2.00
b1s19[8] . -3.892 0.000 -4.448 1.72
b1s19[9] . -3.333 0.000 -6.110 1.50
b1s19[10] . -1.109 1.109 -1.109 1.44
b1s19[11] . 2.775 0.555 -3.330 1.33
b1s19[12] . 0.000 0.000 -7.220 1.00
b1s19[13] b1s19[10] -1.664 0.000 -1.109 1.28
b1s19[14] . -2.084 0.695 -7.641 1.11
b1s19[15] b1s19[13] -9.442 0.000 -2.222 1.28
b1s19[16] . -2.222 0.555 -2.777 1.28
b1s19[17] b1s19[15] -4.448 0.000 1.668 1.28
b1s19[18] . -4.999 0.555 -0.555 1.11
b1s19[19] . -10.050 0.558 -5.583 1.11
b1s19[20] . -4.448 0.000 3.336 1.06
b1s19[21] b1s19[19] -4.443 0.000 -6.665 1.06
b1s19[22] . -6.115 0.000 -0.556 1.00
b1s19[23] b1s19[18] -10.000 0.000 3.889 1.06
b1s19[24] . -1.668 0.556 -2.781 1.00
b1s19[25] b1s19[7] -5.003 -0.556 2.779 1.50
b1s19[26] . -5.002 1.111 5.002 1.11
b1s19[27] . -3.888 0.000 5.554 1.22
b1s19[28] . -7.220 0.000 1.666 1.28
b1s19[29] . -4.448 0.000 3.892 1.22
b1s19[30] b1s19[3] -0.555 0.555 4.999 2.50
b1s19[31] . 1.111 0.000 6.110 1.67
b1s19[32] . -3.890 0.000 2.778 1.56
b1s19[33] . -11.316 0.000 2.263 1.44
b1s19[34] . -8.329 0.000 -2.221 1.61
b1s19[35] . -8.889 1.111 2.222 1.72
b1s19[36] . -2.778 0.000 3.334 1.67
b1s19[37] . -9.442 0.000 -2.222 1.50
b1s19[38] b1s19[36] -0.555 0.555 10.551 1.50
b1s19[39] . -15.568 0.000 8.896 1.33
b1s19[40] b1s19[38] -4.443 -0.555 3.888 1.33
b1s19[41] . -6.666 -0.555 9.999 1.17
b1s19[42] . -5.555 0.000 1.667 1.00