## Set file for basenetpico3.ode on Mon Apr 2 11:27:39 2018 23 Number of equations and auxiliaries 73 Number of parameters # Numerical stuff 1 nout 40 nullcline mesh 8 Qual RK 10000 total 0.1 DeltaT 0 T0 0 Transient 5000 Bound 1e-12 DtMin 1 DtMax 0.001 Tolerance 0.001 Abs. Tolerance 0 Max Delay 100 Eigenvector iterates 0.001 Eigenvector tolerance 0.001 Newton tolerance 0 Poincare plane 1e-05 Boundary value tolerance 1e-05 Boundary value epsilon 20 Boundary value iterates 0 Poincare None 1 Poincare variable 1 Poincare sign 0 Stop on Section 0 Delay flag 10000 Current time 10000 Last Time 1 MyStart 1 INFLAG # Delays 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 # Bndry conds 0 0 0 0 0 0 0 0 0 0 0 0 0 # Old ICs -66.72047402539444 V1 -58.45301729085097 V2 -24.48108237102182 V3 -59.18111325030944 V4 -14.8335152673346 V5 0.344848037132666 H1 0.2083623846905638 H2 0.4522269480122016 H3 0.4143615497844623 H4 0.7150382434491885 H5 0.2687545729226485 M2 0.1529385460014474 M3 0.04201480104286515 M4 # Ending ICs -25.85411358575036 V1 -27.58097985903005 V2 -60.66883562650489 V3 -51.97695158927019 V4 -67.63803039967665 V5 0.3861447085158601 H1 0.2042883421630558 H2 0.4304762227046617 H3 0.3749886328413965 H4 0.7810047570630377 H5 0.2480453778770985 M2 0.08840305005318479 M3 0.05455146123482853 M4 # Parameters 20 C 3 gLE 3.25 gLI -65 ELE -60 ELI 10 gsynE 0 EsynE 60 gsynI -75 EsynI -85 EK 50 ENa -29 V12n -4 kn 1 gKdr -37 V12mp -6 kmp -48 V12hp 8 khp 4000 tauhp 4.5 gNaPe 0.25 gNaPi 10 gAD 2000 Tad2 1500 Tad3 2000 Tad4 0.8 Kad2 1.4 Kad3 0.8 Kad4 -32 V12outpute -8 Koutpute -30 V12outputi -4 Koutputi -20 V12outputp -12 Koutputp 0.6 a12 0.6 b23 0.3 b24 0.125 b31 0.27 b32 0.45 b34 0.015 b41 0.3 b42 0.02 b43 1 Drive1 1 Drive2 1 Drive3 -0.03 c11 0.19 c12 0.58 c13 0.2 c14 0.07000000000000001 c21 0.3 c22 0.4 c24 0.025 c31 1 nf 0 sdum1 0 sdum2 0 sdum3 0 sdum4 0 edum 0 Iapp1 0 Iapp2 0 Iapp3 0 Iapp4 0.2 b25 0.3 b45 0 sdum5 0.045 c15 0 c25 0 c35 0 Iapp5 0.1 a53 0.2 a15 # Graphics 0.7071097251469876 rm -0.4999999999826661 rm 0.4999958366025516 rm 0.7071038372138505 rm 0.5000041633974482 rm -0.4999999999826661 rm 0 rm 0.7071038372138505 rm 0.7071097251469876 rm 0 21 1 1 0 0 22 1 1 10 0 21 1 1 8 0 22 1 1 10 0 23 1 1 5 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 -1000 1000 0 0 3DFlag 1 Timeflag 0 Colorflag 0 Type 1 color scale 0 minscale 10000 xmax 0 xmin 0.8113813996315002 ymax 0.0001830505207180977 ymin 12 zmax -12 zmin 5000 0.0002 0.4057822250761092 2.465488252278072 0 0.08333333333333333 45 Theta 45 Phi 0 xshft 0 yshft 0 zshft 0 xlo 0.0001830505207180977 ylo 0 -80 10000 xhi 0.8113813996315002 yhi 1000 20 # Transpose variables etc V1 2 n columns 1 n rows 1 row skip 1 col skip 1 row 0 # Coupling stuff for H funs 0 0 0 0 0 0 0 0 0 0 0 # Array plot stuff # Array plot stuff 0 Row 1 50 NCols 8 Row 1 0 NRows 1 RowSkip 0 Zmin 0 Zmax # Torus information 0 Torus flag 1=ON 0 Torus period # Range information 0 shoot 0 eq-range stab col 0 shoot flag 1=on 0 eq-range steps 0 eq_range low 10 eq_range high 0 eq_rang e high 1 Range steps 0 Cycle color 1=on 0 Reset data 1=on 0 Use old I.C.s 1=yes 0 Par1 low 20 Par2 low 0 Par1 high 0 Par2 high 1 Par1 hi 0 BVP side 1 color cycle flag 1=on 0 BVP range steps 0 BVP range low 0 BVP range high RHS etc ... dV1/dT=(-INAPE(V1,H1)-IKDR(V1)-ILE(V1)-GSYNI*(B31*FOUTI(V3)+B41*FOUTI(V4)+SDUM1)*(V1-ESYNI)-GSYNE*(C11*DRIVE1+C21*DRIVE2+C31*DRIVE3)*(V1-ESYNE)+IAPP1)/C dV2/dT=(-INAPI(V2,H2)-IAD(V2,M2)-ILI(V2)-GSYNI*(B32*FOUTI(V3)+B42*FOUTI(V4)+SDUM2)*(V2-ESYNI)-GSYNE*(A12*FOUTE(V1)+C22*DRIVE2+C12*DRIVE1+EDUM)*(V2-ESYNE)+IAPP2)/C dV3/dT=(-INAPI(V3,H3)-IAD(V3,M3)-ILI(V3)-GSYNI*(B23*FOUTI(V2)+B43*FOUTI(V4)+SDUM3)*(V3-ESYNI)-GSYNE*(A53*FOUTP(V5)+C13*DRIVE1)*(V3-ESYNE)+IAPP3)/C dV4/dT=(-INAPI(V4,H4)-IAD(V4,M4)-ILI(V4)-GSYNI*(B24*FOUTI(V2)+B34*FOUTI(V3)+SDUM4)*(V4-ESYNI)-GSYNE*(C14*DRIVE1+C24*DRIVE2)*(V4-ESYNE)+IAPP4)/C dV5/dT=(-INAPE(V5,H5)-IKDR(V5)-ILE(V5)-GSYNI*(B25*FOUTI(V2)+B45*FOUTI(V4)+SDUM5)*(V5-ESYNI)-GSYNE*(A15*FOUTE(V1)+C15*DRIVE1+C25*DRIVE2+C35*DRIVE3)*(V5-ESYNE)+IAPP5)/C dH1/dT=(HPINF(V1)-H1)/TAUINF(V1) dH2/dT=(HPINF(V2)-H2)/TAUINF(V2) dH3/dT=(HPINF(V3)-H3)/TAUINF(V3) dH4/dT=(HPINF(V4)-H4)/TAUINF(V4) dH5/dT=(HPINF(V5)-H5)/TAUINF(V5) dM2/dT=(-M2+KAD2*FOUTI(V2))/TAD2 dM3/dT=(-M3+KAD3*FOUTI(V3))/TAD3 dM4/dT=(-M4+KAD4*FOUTI(V4))/TAD4 INH1=B31*FOUTI(V3)+B41*FOUTI(V4) INH2=B32*FOUTI(V3)+B42*FOUTI(V4) INH3=B23*FOUTI(V2)+B43*FOUTI(V4) INH4=B24*FOUTI(V2)+B34*FOUTI(V3) EXC2=A12*FOUTE(V1) FV1=FOUTE(V1) FV2=FOUTI(V2) FV3=FOUTI(V3) FV4=FOUTI(V4) FV5=FOUTE(V5) User-defined functions: FOUTE(V) = 1./(1+EXP((V-V12OUTPUTE)/KOUTPUTE)) FOUTI(V) = 1./(1+EXP((V-V12OUTPUTI)/KOUTPUTI)) FOUTP(V) = 1./(1+EXP((V-V12OUTPUTP)/KOUTPUTP)) NINF(V) = 1./(1+EXP((V-V12N)/KN)) MPINF(V) = 1./(1+EXP((V-V12MP)/KMP)) HPINF(V) = 1./(1+EXP((V-V12HP)/KHP)) TAUINF(V) = TAUHP/COSH((V-V12HP)/(2*KHP)) INAPE(V,H) = GNAPE*MPINF(V)*H*(V-ENA) INAPI(V,H) = GNAPI*MPINF(V)*H*(V-ENA) IKDR(V) = GKDR*NINF(V)^4*(V-EK) IAD(V,M) = GAD*M*(V-EK) ILE(V) = GLE*(V-ELE) ILI(V) = GLI*(V-ELI)