TITLE Kv7-current
COMMENT
Model reproducing cortical M currents, M.H.P. Kole
ENDCOMMENT
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(pS) = (picosiemens)
(um) = (micron)
}
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
PARAMETER {
dt (ms)
v (mV)
vhalf = -48 (mV)
gbar = 20 (pS/um2) :0.002 mho/cm2
}
NEURON {
SUFFIX Kv7
USEION k READ ek WRITE ik
RANGE gbar, ik
}
STATE { m }
ASSIGNED {
ik (mA/cm2)
gk (pS/um2)
ek (mV)
}
INITIAL {
m=alpha(v)/(beta(v)+alpha(v))
}
BREAKPOINT {
SOLVE state METHOD cnexp
ik=(1e-4)*gbar*m*(v-ek)
}
FUNCTION alpha(v(mV)) {
alpha = 0.00623*exp((v-vhalf)/18.76)
}
FUNCTION beta(v(mV)) {
beta = 0.0199*exp(-(v-vhalf)/30.6)
}
DERIVATIVE state {
m' = (1-m)*alpha(v) - m*beta(v)
}