COMMENT
A slow potassium current
Author: Fredrik Edin, 2003
Address: freedin@nada.kth.se
ENDCOMMENT
NEURON {
SUFFIX IKs
USEION k READ ek WRITE ik
RANGE gk, ik, ek, gkbar
GLOBAL qinf, tauq, rinf, taur
}
UNITS {
(mV) = (millivolt)
(mA) = (milliampere)
}
PARAMETER {
gkbar = 0.002 (mho/cm2) <0,1e9>
}
ASSIGNED {
v (mV)
ek (mV)
gk (mho/cm2)
ik (mA/cm2)
qinf
tauq (ms)
rinf
taur (ms)
}
STATE {
r
q
}
BREAKPOINT {
SOLVE state METHOD cnexp
gk = gkbar * q * r
ik = gk * ( v - ek )
}
INITIAL {
rates( v )
q = qinf
r = rinf
}
DERIVATIVE state {
rates( v )
q' = ( qinf - q ) / tauq
r' = ( rinf - r ) / taur
}
PROCEDURE rates( v (mV) ) {
TABLE qinf, rinf, tauq, taur FROM -100 TO 100 WITH 200
UNITSOFF
qinf = 1 / ( 1 + exp( -(34 + v)/6.5 ) )
tauq = 8 / ( exp(-(v+55)/30) + exp((v+55)/30) )
rinf = 1 / ( 1 + exp((65 + v)/6.6 ) )
taur = 100 / ( 1 + exp(-(v+65)/6.8) ) + 100
UNITSON
}