# An example of a parameter file for the multimodule network. # The file name must contain the word SERIES. This file is read by the # simulation program MultiModuleWMNet.hoc and by SimLoop, which # updates the position in this file (Current row). Commented rows # (beginning with #) are not counted. # # The parameters are organized as follows: # A first row with general parameters and parameters concerning the nets # themselves # A second row with cues. Cues have five parameters so this row is # 5 * no of cues long. # A third row with experimental parameters of various length # The rest of the rows specify connections between modules, one connection per # row. External cells belong to module 0, so specify from as 0 for external # stimulation. # # Parameters: # # First row: # type : Type of the net (used by analysis programs for backward compatibility) # Should always be 2 for this type of network # nmod : Number of modules # nrow : The number of rows that this simulation spans # t : The length of the simulation in ms # dt : The time step in ms # Ecell: The type of excitatory cell (1 is the only choice right now) # NI : No of I-cells # NE : No of E-cells # One can specify several Ecell-NI-NE triplets after one another, one for # each module in the network # # Second row: # CueT : Time of cue # CuePos : Length of cue. # CuePos : Position of cue as a cell index (cells are placed in an array with # I-cells of first module followed by E-cells of first module # followed by cells in further modules. # CueW : Width of cue in cells. # CueAmp : Amplitude of the cue in uA per cm2 # # Remaining rows: # to : Connection to module # from : Connection from module # deldist : The delay distribution 0 = no distribution, # 1 = one-point distribution # 2 = Erlang (gamma) distribution # mu : Mean of delay distribution in ms # s2 : Variance of delay distribution in (ms)^2 # I->E : Position of gaba synapses onto E-cell, # 0 = soma, 1 = proximal dendrite, 2 = distal dendrite # E->E : The same for E-cells. Combinations of 0, 1 and 2 can be specified, # : but number must not begin with 0. # relNMDA : The relative amount of excitatory (NMDA+AMPA) current passing # through NMDA channels. # Ii : Synaptic weight from I-cells to I-cells in mS per cm2 # Ie : Synaptic weight from E-cells to I-cells in mS per cm2 # Ei : Synaptic weight from I-cells to E-cells in mS per cm2 # Ee : Synaptic weight from E-cells to E-cells in mS per cm2 # Jpii : Height of connection curve (a gaussian on top of a box) connecting # I-cells to I-cells # stdii : Standard deviation of that connection curve in radians. # Jpie : As above for connection from I-cells to E-cells # stdie : Standard deviation of that connection curve in radians. # Jpei : As above for connection from E-cells to I-cells # stdei : Standard deviation of that connection curve in radians. # Jpee : As above for connection from E-cells to E-cells # stdee : Standard deviation of that connection curve in radians. Current row: 00000 #### # 1# 30% NMDA 15ms delay 0% asymmetry #################################################################################################### #type nmod nrow t0 t dt Icell-1 Ecell-1 NI-1 NE-1 Icell-2 Ecell-2 NI-2 NE-2 Save 3 2 13 100 200 0.02 1 1 32 128 1 1 32 128 #Qtim1 Qlen1 Qpos1 Qwid1 Qamp1 Qtim2 Qlen2 Qpos2 Qwid2 Qamp2 1000 500 55 19 1 1000 500 215 19 1 #EXP -1 #modul-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 1 1 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 1 1 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 1 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 2 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 2 2 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 2 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 1 1 15 0 0 21 1 0 0 0 0.039 -1 -1 -1 -1 -1 -1 3.2 0.2 2 1 1 15 0 0 21 0 0 0 0 0.097 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 1 0 0 0 0.039 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 0 0 0 0 0.097 -1 -1 -1 -1 -1 -1 3.2 0.2 #### # 2# 30% NMDA 15ms delay 100% asymmetry #################################################################################################### #type nmod nrow t0 t dt Icell-1 Ecell-1 NI-1 NE-1 Icell-2 Ecell-2 NI-2 NE-2 Save 3 2 11 100 200 0.02 1 1 32 128 1 1 32 128 #Qtim1 Qlen1 Qpos1 Qwid1 Qamp1 Qtim2 Qlen2 Qpos2 Qwid2 Qamp2 1000 500 55 19 1 1000 500 215 19 1 #EXP -1 #modul-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 1 1 0 0 0 0 21 1 0.65 0.294 1.16 0.393 -1 -1 -1 -1 -1 -1 3.2 0.2 1 1 0 0 0 0 21 0 0 0.726 0 0.970 -1 -1 -1 -1 -1 -1 3.2 0.2 1 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 2 0 0 0 0 21 1 0.65 0.294 1.16 0.315 -1 -1 -1 -1 -1 -1 3.2 0.2 2 2 0 0 0 0 21 0 0 0.726 0 0.776 -1 -1 -1 -1 -1 -1 3.2 0.2 2 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 1 1 15 0 0 21 1 0 0 0 0.078 -1 -1 -1 -1 -1 -1 3.2 0.2 2 1 1 15 0 0 21 0 0 0 0 0.194 -1 -1 -1 -1 -1 -1 3.2 0.2 #### # 3# 30% NMDA 15ms delay 25% asymmetry #################################################################################################### #type nmod nrow t0 t dt Icell-1 Ecell-1 NI-1 NE-1 Icell-2 Ecell-2 NI-2 NE-2 Save 3 2 13 100 200 0.02 1 1 32 128 1 1 32 128 #Qtim1 Qlen1 Qpos1 Qwid1 Qamp1 Qtim2 Qlen2 Qpos2 Qwid2 Qamp2 1000 500 55 19 1 1000 500 215 19 1 #EXP -1 #modul-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 1 1 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 1 1 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 1 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 2 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 2 2 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 2 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 1 1 15 0 0 21 1 0 0 0 0.049 -1 -1 -1 -1 -1 -1 3.2 0.2 2 1 1 15 0 0 21 0 0 0 0 0.121 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 1 0 0 0 0.029 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 0 0 0 0 0.073 -1 -1 -1 -1 -1 -1 3.2 0.2 #### # 4# 30% NMDA 15ms delay 50% asymmetry #################################################################################################### #type nmod nrow t0 t dt Icell-1 Ecell-1 NI-1 NE-1 Icell-2 Ecell-2 NI-2 NE-2 Save 3 2 13 100 200 0.02 1 1 32 128 1 1 32 128 #Qtim1 Qlen1 Qpos1 Qwid1 Qamp1 Qtim2 Qlen2 Qpos2 Qwid2 Qamp2 1000 500 55 19 1 1000 500 215 19 1 #EXP -1 #modul-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 1 1 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 1 1 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 1 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 2 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 2 2 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 2 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 1 1 15 0 0 21 1 0 0 0 0.059 -1 -1 -1 -1 -1 -1 3.2 0.2 2 1 1 15 0 0 21 0 0 0 0 0.146 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 1 0 0 0 0.019 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 0 0 0 0 0.048 -1 -1 -1 -1 -1 -1 3.2 0.2 #### # 5# 30% NMDA 15ms delay 75% asymmetry #################################################################################################### #type nmod nrow t0 t dt Icell-1 Ecell-1 NI-1 NE-1 Icell-2 Ecell-2 NI-2 NE-2 Save 3 2 13 100 200 0.02 1 1 32 128 1 1 32 128 #Qtim1 Qlen1 Qpos1 Qwid1 Qamp1 Qtim2 Qlen2 Qpos2 Qwid2 Qamp2 1000 500 55 19 1 1000 500 215 19 1 #EXP -1 #modul-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 1 1 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 1 1 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 1 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 2 0 0 0 0 21 1 0.65 0.294 1.16 0.354 -1 -1 -1 -1 -1 -1 3.2 0.2 2 2 0 0 0 0 21 0 0 0.726 0 0.873 -1 -1 -1 -1 -1 -1 3.2 0.2 2 0 0 0 0 0 2 0 0 0.0024 0 0.011 -1 -1 -1 -1 -1 -1 -1 -1 #modul-2-1 #to from deldist mu s2 I->E E->E relNMDA Ii Ie Ei Ee Jpii stdii Jpie stdie Jpei stdei Jpee stdee 2 1 1 15 0 0 21 1 0 0 0 0.068 -1 -1 -1 -1 -1 -1 3.2 0.2 2 1 1 15 0 0 21 0 0 0 0 0.170 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 1 0 0 0 0.010 -1 -1 -1 -1 -1 -1 3.2 0.2 1 2 1 15 0 0 21 0 0 0 0 0.024 -1 -1 -1 -1 -1 -1 3.2 0.2