NEURON files from the paper: A modeling study suggesting how a reduction in the context-dependent input on CA1 pyramidal neurons could generate schizophrenic behavior by M. Migliore, I. De Blasi, D. Tegolo, R. Migliore, Neural Networks,(2011), doi:10.1016/j.neunet.2011.01.001. With an extensive series of simulations we show how and to what extent a pathological hypofunction of the Perforant Path input can alter the normal recall of objects on which the neuron has been previously tuned. The hoc file "sim_9068802-test" is a typical simulation file that illustrates the binding process. It tests all the 462 possible 5-ples of obliques in cell 9068802 and prints to context033s1-modeldb.txt those that, during one of the trials (seed=1), with a specific context (0.33nA), and a specific background noise (0.4) generate a valid somatic spike (see the paper for a definition of a valid spike). The results generated by 10 trials are stored in the file "c033-all-seeds.txt", which is used to calculate the average presence of a given oblique in a valid 5-ple. This simulation file is for illustration purposes only. It can be launched on a parallel system, but requires some editing to run the full (and quite long) simulation. Ask the authors for more info if you want to run a full sim. The file average.hoc reads the c033-all-seeds.txt and reproduces the histogram corresponding to the context 0.33 nA in Fig.4 (purple bars). In the paper, Fig.4 demonstrates that the presence of each oblique, on average, is relatively independent from the context. Questions on how to use this model should be directed to michele.migliore@pa.ibf.cnr.it Changelog ========= * 20220924: Update MOD files to avoid declaring variables and functions with the same name. See https://github.com/neuronsimulator/nrn/pull/1992