COMMENT
K_dr channel from Schweighofer et al 1999.
The referred model is an inferior olive neuron
B. Torben-Nielsen @ HUJI, 21-10-2010
ENDCOMMENT
NEURON {
SUFFIX ioKdr
USEION k READ ek WRITE ik
RANGE gbar,g,i,ninf,taun,n : now i can access these variables
}
UNITS {
(S) = (siemens)
(mS) = (millisiemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gbar = 18 (mS/cm2)
ek = -75 (mV)
}
ASSIGNED {
v (mV)
ik (mA/cm2)
i (mA/cm2)
g (mS/cm2)
ninf
taun (ms)
}
STATE { n }
INITIAL {
rates(v)
n = ninf
}
BREAKPOINT {
rates(v)
SOLVE states METHOD cnexp
g = gbar *n*n*n*n
i = g * (v - ek)*(0.001)
ik = i
}
DERIVATIVE states {
n' = (ninf -n)/taun
}
PROCEDURE rates(v (mV)) {
LOCAL a_n , b_n
UNITSOFF
if(fabs(v+41.0) < 1e-6) {
: printf("v=%g\n", v)
a_n=(v+41.00001)/( 1-exp( -(v+41.00001)/10 ) )
} else {
a_n=(v+41)/( 1-exp( -(v+41)/10 ) )
}
b_n=12.5*exp( -(v+51)/80 )
ninf=a_n/(a_n+b_n)
taun=10/( a_n+b_n ) : was 5
UNITSON
}