/* Created by Language version: 7.7.0 */
/* VECTORIZED */
#define NRN_VECTORIZED 1
#include <stdio.h>
#include <stdlib.h>
#include <math.h>
#include "scoplib_ansi.h"
#undef PI
#define nil 0
#include "md1redef.h"
#include "section.h"
#include "nrniv_mf.h"
#include "md2redef.h"
#if METHOD3
extern int _method3;
#endif
#if !NRNGPU
#undef exp
#define exp hoc_Exp
extern double hoc_Exp(double);
#endif
#define nrn_init _nrn_init__SinClamp
#define _nrn_initial _nrn_initial__SinClamp
#define nrn_cur _nrn_cur__SinClamp
#define _nrn_current _nrn_current__SinClamp
#define nrn_jacob _nrn_jacob__SinClamp
#define nrn_state _nrn_state__SinClamp
#define _net_receive _net_receive__SinClamp
#define _threadargscomma_ _p, _ppvar, _thread, _nt,
#define _threadargsprotocomma_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt,
#define _threadargs_ _p, _ppvar, _thread, _nt
#define _threadargsproto_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt
/*SUPPRESS 761*/
/*SUPPRESS 762*/
/*SUPPRESS 763*/
/*SUPPRESS 765*/
extern double *getarg();
/* Thread safe. No static _p or _ppvar. */
#define t _nt->_t
#define dt _nt->_dt
#define del _p[0]
#define dur _p[1]
#define pkamp _p[2]
#define freq _p[3]
#define phase _p[4]
#define bias _p[5]
#define i _p[6]
#define v _p[7]
#define _g _p[8]
#define _nd_area *_ppvar[0]._pval
#if MAC
#if !defined(v)
#define v _mlhv
#endif
#if !defined(h)
#define h _mlhh
#endif
#endif
#if defined(__cplusplus)
extern "C" {
#endif
static int hoc_nrnpointerindex = -1;
static Datum* _extcall_thread;
static Prop* _extcall_prop;
/* external NEURON variables */
/* declaration of user functions */
static int _mechtype;
extern void _nrn_cacheloop_reg(int, int);
extern void hoc_register_prop_size(int, int, int);
extern void hoc_register_limits(int, HocParmLimits*);
extern void hoc_register_units(int, HocParmUnits*);
extern void nrn_promote(Prop*, int, int);
extern Memb_func* memb_func;
#define NMODL_TEXT 1
#if NMODL_TEXT
static const char* nmodl_file_text;
static const char* nmodl_filename;
extern void hoc_reg_nmodl_text(int, const char*);
extern void hoc_reg_nmodl_filename(int, const char*);
#endif
extern Prop* nrn_point_prop_;
static int _pointtype;
static void* _hoc_create_pnt(_ho) Object* _ho; { void* create_point_process();
return create_point_process(_pointtype, _ho);
}
static void _hoc_destroy_pnt();
static double _hoc_loc_pnt(_vptr) void* _vptr; {double loc_point_process();
return loc_point_process(_pointtype, _vptr);
}
static double _hoc_has_loc(_vptr) void* _vptr; {double has_loc_point();
return has_loc_point(_vptr);
}
static double _hoc_get_loc_pnt(_vptr)void* _vptr; {
double get_loc_point_process(); return (get_loc_point_process(_vptr));
}
extern void _nrn_setdata_reg(int, void(*)(Prop*));
static void _setdata(Prop* _prop) {
_extcall_prop = _prop;
}
static void _hoc_setdata(void* _vptr) { Prop* _prop;
_prop = ((Point_process*)_vptr)->_prop;
_setdata(_prop);
}
/* connect user functions to hoc names */
static VoidFunc hoc_intfunc[] = {
0,0
};
static Member_func _member_func[] = {
"loc", _hoc_loc_pnt,
"has_loc", _hoc_has_loc,
"get_loc", _hoc_get_loc_pnt,
0, 0
};
/* declare global and static user variables */
#define PI PI_SinClamp
double PI = 3.14159;
/* some parameters have upper and lower limits */
static HocParmLimits _hoc_parm_limits[] = {
0,0,0
};
static HocParmUnits _hoc_parm_units[] = {
"del", "ms",
"dur", "ms",
"pkamp", "nA",
"freq", "Hz",
"phase", "rad",
"bias", "nA",
"i", "nA",
0,0
};
/* connect global user variables to hoc */
static DoubScal hoc_scdoub[] = {
"PI_SinClamp", &PI_SinClamp,
0,0
};
static DoubVec hoc_vdoub[] = {
0,0,0
};
static double _sav_indep;
static void nrn_alloc(Prop*);
static void nrn_init(_NrnThread*, _Memb_list*, int);
static void nrn_state(_NrnThread*, _Memb_list*, int);
static void nrn_cur(_NrnThread*, _Memb_list*, int);
static void nrn_jacob(_NrnThread*, _Memb_list*, int);
static void _hoc_destroy_pnt(_vptr) void* _vptr; {
destroy_point_process(_vptr);
}
/* connect range variables in _p that hoc is supposed to know about */
static const char *_mechanism[] = {
"7.7.0",
"SinClamp",
"del",
"dur",
"pkamp",
"freq",
"phase",
"bias",
0,
"i",
0,
0,
0};
extern Prop* need_memb(Symbol*);
static void nrn_alloc(Prop* _prop) {
Prop *prop_ion;
double *_p; Datum *_ppvar;
if (nrn_point_prop_) {
_prop->_alloc_seq = nrn_point_prop_->_alloc_seq;
_p = nrn_point_prop_->param;
_ppvar = nrn_point_prop_->dparam;
}else{
_p = nrn_prop_data_alloc(_mechtype, 9, _prop);
/*initialize range parameters*/
del = 5;
dur = 200;
pkamp = 1;
freq = 1;
phase = 0;
bias = 0;
}
_prop->param = _p;
_prop->param_size = 9;
if (!nrn_point_prop_) {
_ppvar = nrn_prop_datum_alloc(_mechtype, 2, _prop);
}
_prop->dparam = _ppvar;
/*connect ionic variables to this model*/
}
static void _initlists();
extern Symbol* hoc_lookup(const char*);
extern void _nrn_thread_reg(int, int, void(*)(Datum*));
extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
extern void _cvode_abstol( Symbol**, double*, int);
void _sinclamp_reg() {
int _vectorized = 1;
_initlists();
_pointtype = point_register_mech(_mechanism,
nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init,
hoc_nrnpointerindex, 1,
_hoc_create_pnt, _hoc_destroy_pnt, _member_func);
_mechtype = nrn_get_mechtype(_mechanism[1]);
_nrn_setdata_reg(_mechtype, _setdata);
#if NMODL_TEXT
hoc_reg_nmodl_text(_mechtype, nmodl_file_text);
hoc_reg_nmodl_filename(_mechtype, nmodl_filename);
#endif
hoc_register_prop_size(_mechtype, 9, 2);
hoc_register_dparam_semantics(_mechtype, 0, "area");
hoc_register_dparam_semantics(_mechtype, 1, "pntproc");
hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
ivoc_help("help ?1 SinClamp D:/Projects/SchreglmannEtAl2020/CCTC_model/modfiles/sinclamp.mod\n");
hoc_register_limits(_mechtype, _hoc_parm_limits);
hoc_register_units(_mechtype, _hoc_parm_units);
}
static int _reset;
static char *modelname = "";
static int error;
static int _ninits = 0;
static int _match_recurse=1;
static void _modl_cleanup(){ _match_recurse=1;}
static void initmodel(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {
int _i; double _save;{
}
}
static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
_ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
_p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if EXTRACELLULAR
_nd = _ml->_nodelist[_iml];
if (_nd->_extnode) {
_v = NODEV(_nd) +_nd->_extnode->_v[0];
}else
#endif
{
#if CACHEVEC
if (use_cachevec) {
_v = VEC_V(_ni[_iml]);
}else
#endif
{
_nd = _ml->_nodelist[_iml];
_v = NODEV(_nd);
}
}
v = _v;
initmodel(_p, _ppvar, _thread, _nt);
}
}
static double _nrn_current(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt, double _v){double _current=0.;v=_v;{ {
at_time ( _nt, del ) ;
at_time ( _nt, del + dur ) ;
if ( t < del ) {
i = 0.0 ;
}
else {
if ( t < del + dur ) {
i = pkamp * sin ( 2.0 * PI * freq * ( t - del ) / 1000.0 + phase ) + bias ;
}
else {
i = 0.0 ;
}
}
}
_current += i;
} return _current;
}
static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
#if CACHEVEC
_ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
_p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if EXTRACELLULAR
_nd = _ml->_nodelist[_iml];
if (_nd->_extnode) {
_v = NODEV(_nd) +_nd->_extnode->_v[0];
}else
#endif
{
#if CACHEVEC
if (use_cachevec) {
_v = VEC_V(_ni[_iml]);
}else
#endif
{
_nd = _ml->_nodelist[_iml];
_v = NODEV(_nd);
}
}
_g = _nrn_current(_p, _ppvar, _thread, _nt, _v + .001);
{ _rhs = _nrn_current(_p, _ppvar, _thread, _nt, _v);
}
_g = (_g - _rhs)/.001;
_g *= 1.e2/(_nd_area);
_rhs *= 1.e2/(_nd_area);
#if CACHEVEC
if (use_cachevec) {
VEC_RHS(_ni[_iml]) += _rhs;
}else
#endif
{
NODERHS(_nd) += _rhs;
}
if (_nt->_nrn_fast_imem) { _nt->_nrn_fast_imem->_nrn_sav_rhs[_ni[_iml]] += _rhs; }
#if EXTRACELLULAR
if (_nd->_extnode) {
*_nd->_extnode->_rhs[0] += _rhs;
}
#endif
}
}
static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; int _iml, _cntml;
#if CACHEVEC
_ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
_p = _ml->_data[_iml];
_nd = _ml->_nodelist[_iml];
#if CACHEVEC
if (use_cachevec) {
VEC_D(_ni[_iml]) -= _g;
}else
#endif
{
NODED(_nd) -= _g;
}
if (_nt->_nrn_fast_imem) { _nt->_nrn_fast_imem->_nrn_sav_d[_ni[_iml]] -= _g; }
#if EXTRACELLULAR
if (_nd->_extnode) {
*_nd->_extnode->_d[0] += _g;
}
#endif
}
}
static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type) {
}
static void terminal(){}
static void _initlists(){
double _x; double* _p = &_x;
int _i; static int _first = 1;
if (!_first) return;
_first = 0;
}
#if defined(__cplusplus)
} /* extern "C" */
#endif
#if NMODL_TEXT
static const char* nmodl_filename = "sinclamp.mod";
static const char* nmodl_file_text =
"COMMENT\n"
"Since this is an electrode current, positive values of i depolarize the cell\n"
"and in the presence of the extracellular mechanism there will be a change\n"
"in vext since i is not a transmembrane current but a current injected\n"
"directly to the inside of the cell.\n"
"By Kelvin and Ted, 2007\n"
"https://www.neuron.yale.edu/phpBB/viewtopic.php?t=897\n"
"ENDCOMMENT\n"
"\n"
"NEURON {\n"
" POINT_PROCESS SinClamp\n"
" RANGE del, dur, pkamp, freq, phase, bias\n"
" ELECTRODE_CURRENT i\n"
"}\n"
"\n"
"UNITS {\n"
" (nA) = (nanoamp)\n"
" }\n"
"\n"
"PARAMETER {\n"
" del=5 (ms)\n"
" dur=200 (ms)\n"
" pkamp=1 (nA)\n"
" freq=1 (Hz)\n"
" phase=0 (rad)\n"
" bias=0 (nA)\n"
" PI=3.14159265358979323846\n"
"}\n"
"\n"
"ASSIGNED {\n"
" i (nA)\n"
"}\n"
"\n"
"BREAKPOINT {\n"
" at_time(del)\n"
" at_time(del + dur)\n"
"\n"
" if (t < del) {\n"
" i=0 \n"
" }else{ \n"
" if (t < del+dur) {\n"
" i = pkamp*sin(2*PI*freq*(t-del)/1000+phase)+bias\n"
" }else{ \n"
" i = 0\n"
"}}}\n"
;
#endif