//FILE IN USE 09/30/2004 -- present. //genesis - genesis2.2 script, J Hanson 5/02 //axon rebuilt with hillock, initial segment, nodes and internodal // segments 06/25/2004 according to Shen et al (1999). // 06/28/2004: added KCNQ to axon, added G_mult_KCNQ_dend and G_mult_KCNQ_axon // 09/30/2004: changed dendritic subclassifications to match the data of // Hanson & Smith, 2004. float PI = 3.14159 function make_GP_comps float len, dia, surf, rad, vol, core_vol, shell_vol float rad_core, shell_vol int i /* make spherical soma prototype */ len = 0 dia = 1 rad = {dia}/2.0 rad_core = rad - {shell_thick} surf = 4*{PI}*rad*rad vol = 4/3*{PI}*rad*rad*rad core_vol = 4/3*{PI}*rad_core*rad_core*rad_core shell_vol = vol - core_vol if (!({exists GP_soma})) create compartment GP_soma end setfield GP_soma Cm {{CM}*surf} Ra {8.0*{RA}/({dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} /* put channels in soma */ copy Ca_HVA_GP GP_soma/Ca_HVA_GP_somahill addmsg GP_soma GP_soma/Ca_HVA_GP_somahill VOLTAGE Vm addmsg GP_soma/Ca_HVA_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Ca_HVA_GP_somahill Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_soma}*{G_mult}} copy K_ahp_GP GP_soma/K_ahp_GP_somahill addmsg GP_soma GP_soma/K_ahp_GP_somahill VOLTAGE Vm addmsg GP_soma/K_ahp_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/K_ahp_GP_somahill Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_soma}*{G_mult}} copy Ca_GP_nernst GP_soma/Ca_GP_nernst copy Ca_GP_conc GP_soma/Ca_GP_conc addmsg GP_soma/Ca_HVA_GP_somahill GP_soma/Ca_GP_conc I_Ca Ik addmsg GP_soma/Ca_GP_conc GP_soma/Ca_HVA_GP_somahill CONCEN Ca addmsg GP_soma/Ca_GP_conc GP_soma/K_ahp_GP_somahill CONCEN Ca addmsg GP_soma/Ca_GP_conc GP_soma/Ca_GP_nernst CIN Ca addmsg GP_soma/Ca_GP_nernst GP_soma/Ca_HVA_GP_somahill EK E setfield GP_soma/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_soma/Na_fast_GP_somahill addmsg GP_soma GP_soma/Na_fast_GP_somahill VOLTAGE Vm addmsg GP_soma/Na_fast_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Na_fast_GP_somahill Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_soma}*{G_mult}} copy Na_slow_GP GP_soma/Na_slow_GP_somahill addmsg GP_soma GP_soma/Na_slow_GP_somahill VOLTAGE Vm addmsg GP_soma/Na_slow_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Na_slow_GP_somahill Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_soma}*{G_mult}} copy Kv3_GP GP_soma/Kv3_GP_somahill addmsg GP_soma GP_soma/Kv3_GP_somahill VOLTAGE Vm addmsg GP_soma/Kv3_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Kv3_GP_somahill Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_soma}*{G_mult}} copy Kv2_GP GP_soma/Kv2_GP_somahill addmsg GP_soma GP_soma/Kv2_GP_somahill VOLTAGE Vm addmsg GP_soma/Kv2_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Kv2_GP_somahill Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_soma}*{G_mult}} copy Kv4_fast_GP GP_soma/Kv4_fast_GP_somahill addmsg GP_soma GP_soma/Kv4_fast_GP_somahill VOLTAGE Vm addmsg GP_soma/Kv4_fast_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Kv4_fast_GP_somahill Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_soma}*{G_mult}} copy Kv4_slow_GP GP_soma/Kv4_slow_GP_somahill addmsg GP_soma GP_soma/Kv4_slow_GP_somahill VOLTAGE Vm addmsg GP_soma/Kv4_slow_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/Kv4_slow_GP_somahill Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_soma}*{G_mult}} copy KCNQ_GP GP_soma/KCNQ_GP_somahill addmsg GP_soma GP_soma/KCNQ_GP_somahill VOLTAGE Vm addmsg GP_soma/KCNQ_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/KCNQ_GP_somahill Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_soma}*{G_mult}} copy h_HCN_GP GP_soma/h_HCN_GP_somahill addmsg GP_soma GP_soma/h_HCN_GP_somahill VOLTAGE Vm addmsg GP_soma/h_HCN_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/h_HCN_GP_somahill Gbar \ {{G_h_HCN_GP}*surf*{G_mult}} copy h_HCN2_GP GP_soma/h_HCN2_GP_somahill addmsg GP_soma GP_soma/h_HCN2_GP_somahill VOLTAGE Vm addmsg GP_soma/h_HCN2_GP_somahill GP_soma CHANNEL Gk Ek setfield GP_soma/h_HCN2_GP_somahill Gbar \ {{G_h_HCN2_GP}*surf*{G_mult}} /* make axon hillock prototype --> extension of soma */ len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2.0}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_axHill})) create compartment GP_axHill end setfield GP_axHill Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} /* put channels in axon hillock --> same as soma */ copy Ca_HVA_GP GP_axHill/Ca_HVA_GP_somahill addmsg GP_axHill GP_axHill/Ca_HVA_GP_somahill VOLTAGE Vm addmsg GP_axHill/Ca_HVA_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Ca_HVA_GP_somahill Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_soma}*{G_mult}} copy K_ahp_GP GP_axHill/K_ahp_GP_somahill addmsg GP_axHill GP_axHill/K_ahp_GP_somahill VOLTAGE Vm addmsg GP_axHill/K_ahp_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/K_ahp_GP_somahill Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_soma}*{G_mult}} copy Ca_GP_nernst GP_axHill/Ca_GP_nernst copy Ca_GP_conc GP_axHill/Ca_GP_conc addmsg GP_axHill/Ca_HVA_GP_somahill GP_axHill/Ca_GP_conc I_Ca Ik addmsg GP_axHill/Ca_GP_conc GP_axHill/Ca_HVA_GP_somahill CONCEN Ca addmsg GP_axHill/Ca_GP_conc GP_axHill/K_ahp_GP_somahill CONCEN Ca addmsg GP_axHill/Ca_GP_conc GP_axHill/Ca_GP_nernst CIN Ca addmsg GP_axHill/Ca_GP_nernst GP_axHill/Ca_HVA_GP_somahill EK E setfield GP_axHill/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_axHill/Na_fast_GP_somahill addmsg GP_axHill GP_axHill/Na_fast_GP_somahill VOLTAGE Vm addmsg GP_axHill/Na_fast_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Na_fast_GP_somahill Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_soma}*{G_mult}} copy Na_slow_GP GP_axHill/Na_slow_GP_somahill addmsg GP_axHill GP_axHill/Na_slow_GP_somahill VOLTAGE Vm addmsg GP_axHill/Na_slow_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Na_slow_GP_somahill Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_soma}*{G_mult}} copy Kv3_GP GP_axHill/Kv3_GP_somahill addmsg GP_axHill GP_axHill/Kv3_GP_somahill VOLTAGE Vm addmsg GP_axHill/Kv3_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Kv3_GP_somahill Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_soma}*{G_mult}} copy Kv2_GP GP_axHill/Kv2_GP_somahill addmsg GP_axHill GP_axHill/Kv2_GP_somahill VOLTAGE Vm addmsg GP_axHill/Kv2_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Kv2_GP_somahill Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_soma}*{G_mult}} copy Kv4_fast_GP GP_axHill/Kv4_fast_GP_somahill addmsg GP_axHill GP_axHill/Kv4_fast_GP_somahill VOLTAGE Vm addmsg GP_axHill/Kv4_fast_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Kv4_fast_GP_somahill Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_soma}*{G_mult}} copy Kv4_slow_GP GP_axHill/Kv4_slow_GP_somahill addmsg GP_axHill GP_axHill/Kv4_slow_GP_somahill VOLTAGE Vm addmsg GP_axHill/Kv4_slow_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/Kv4_slow_GP_somahill Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_soma}*{G_mult}} copy KCNQ_GP GP_axHill/KCNQ_GP_somahill addmsg GP_axHill GP_axHill/KCNQ_GP_somahill VOLTAGE Vm addmsg GP_axHill/KCNQ_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/KCNQ_GP_somahill Gbar \ {{G_KCNQ_GP}*surf*{G_mult}} copy h_HCN_GP GP_axHill/h_HCN_GP_somahill addmsg GP_axHill GP_axHill/h_HCN_GP_somahill VOLTAGE Vm addmsg GP_axHill/h_HCN_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/h_HCN_GP_somahill Gbar \ {{G_h_HCN_GP}*surf*{G_mult}} copy h_HCN2_GP GP_axHill/h_HCN2_GP_somahill addmsg GP_axHill GP_axHill/h_HCN2_GP_somahill VOLTAGE Vm addmsg GP_axHill/h_HCN2_GP_somahill GP_axHill CHANNEL Gk Ek setfield GP_axHill/h_HCN2_GP_somahill Gbar \ {{G_h_HCN2_GP}*surf*{G_mult}} /* make axon initial segment prototype--> low Rm */ len = 1 dia = 1 rad = {dia} / 2 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (!({exists GP_axIS})) create compartment GP_axIS end setfield GP_axIS Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_ax} initVm {EREST_ACT} Rm {{RM_ax}/surf} inject 0.0 \ dia {dia} len {len} /* put channels in axon initial segment */ copy Na_fast_GP GP_axIS/Na_fast_GP_IS addmsg GP_axIS GP_axIS/Na_fast_GP_IS VOLTAGE Vm addmsg GP_axIS/Na_fast_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Na_fast_GP_IS Gbar \ {{G_Na_fast_GP}*surf*{G_mult_Na_IS}*{G_mult}} copy Na_slow_GP GP_axIS/Na_slow_GP_IS addmsg GP_axIS GP_axIS/Na_slow_GP_IS VOLTAGE Vm addmsg GP_axIS/Na_slow_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Na_slow_GP_IS Gbar \ {{G_Na_slow_GP}*surf*{G_mult_Na_IS}*{G_mult}} copy Kv4_fast_GP GP_axIS/Kv4_fast_GP_IS addmsg GP_axIS GP_axIS/Kv4_fast_GP_IS VOLTAGE Vm addmsg GP_axIS/Kv4_fast_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Kv4_fast_GP_IS Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_axon}*{G_mult}} copy Kv4_slow_GP GP_axIS/Kv4_slow_GP_IS addmsg GP_axIS GP_axIS/Kv4_slow_GP_IS VOLTAGE Vm addmsg GP_axIS/Kv4_slow_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Kv4_slow_GP_IS Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_axon}*{G_mult}} copy Kv3_GP GP_axIS/Kv3_GP_IS addmsg GP_axIS GP_axIS/Kv3_GP_IS VOLTAGE Vm addmsg GP_axIS/Kv3_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Kv3_GP_IS Gbar \ {{G_Kv3_GP}*surf*{G_mult_Kdr_IS}*{G_mult}} copy Kv2_GP GP_axIS/Kv2_GP_IS addmsg GP_axIS GP_axIS/Kv2_GP_IS VOLTAGE Vm addmsg GP_axIS/Kv2_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/Kv2_GP_IS Gbar \ {{G_Kv2_GP}*surf*{G_mult_Kdr_IS}*{G_mult}} copy KCNQ_GP GP_axIS/KCNQ_GP_IS addmsg GP_axIS GP_axIS/KCNQ_GP_IS VOLTAGE Vm addmsg GP_axIS/KCNQ_GP_IS GP_axIS CHANNEL Gk Ek setfield GP_axIS/KCNQ_GP_IS Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_axon}*{G_mult}} /* make axon internodal segment prototype--> low Cm, high Rm, no chans */ len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (!({exists GP_axIN})) create compartment GP_axIN end setfield GP_axIN Cm {{CM_my}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_ax} initVm {EREST_ACT} Rm {{RM_my}/surf} inject 0.0 \ dia {dia} len {len} // no channels in axIN segments. /* make axon node prototype--> same characteristics as initial segment */ len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (!({exists GP_axNode})) create compartment GP_axNode end setfield GP_axNode Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_ax} initVm {EREST_ACT} Rm {{RM_ax}/surf} inject 0.0 \ dia {dia} len {len} /* put channels in node--> exclude NaP to prevent spontaneous initiation */ copy Na_fast_GP GP_axNode/Na_fast_GP_node addmsg GP_axNode GP_axNode/Na_fast_GP_node VOLTAGE Vm addmsg GP_axNode/Na_fast_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Na_fast_GP_node Gbar \ {{G_Na_fast_GP}*surf*{G_mult_Na_axon}*{G_mult}} /* copy Na_slow_GP GP_axNode/Na_slow_GP_node addmsg GP_axNode GP_axNode/Na_slow_GP_node VOLTAGE Vm addmsg GP_axNode/Na_slow_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Na_slow_GP_node Gbar \ {{G_Na_slow_GP}*surf*{G_mult_Na_axon}*{G_mult}} */ copy Kv4_fast_GP GP_axNode/Kv4_fast_GP_node addmsg GP_axNode GP_axNode/Kv4_fast_GP_node VOLTAGE Vm addmsg GP_axNode/Kv4_fast_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Kv4_fast_GP_node Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_axon}*{G_mult}} copy Kv4_slow_GP GP_axNode/Kv4_slow_GP_node addmsg GP_axNode GP_axNode/Kv4_slow_GP_node VOLTAGE Vm addmsg GP_axNode/Kv4_slow_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Kv4_slow_GP_node Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_axon}*{G_mult}} copy Kv3_GP GP_axNode/Kv3_GP_node addmsg GP_axNode GP_axNode/Kv3_GP_node VOLTAGE Vm addmsg GP_axNode/Kv3_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Kv3_GP_node Gbar \ {{G_Kv3_GP}*surf*{G_mult_Kdr_axon}*{G_mult}} copy Kv2_GP GP_axNode/Kv2_GP_node addmsg GP_axNode GP_axNode/Kv2_GP_node VOLTAGE Vm addmsg GP_axNode/Kv2_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/Kv2_GP_node Gbar \ {{G_Kv2_GP}*surf*{G_mult_Kdr_axon}*{G_mult}} copy KCNQ_GP GP_axNode/KCNQ_GP_node addmsg GP_axNode GP_axNode/KCNQ_GP_node VOLTAGE Vm addmsg GP_axNode/KCNQ_GP_node GP_axNode CHANNEL Gk Ek setfield GP_axNode/KCNQ_GP_node Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_axon}*{G_mult}} // Dendritic prototype = dendrite_p len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dendrite_p})) create compartment GP_dendrite_p end setfield GP_dendrite_p Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dendrite copy Ca_HVA_GP GP_dendrite_p/Ca_HVA_GP addmsg GP_dendrite_p GP_dendrite_p/Ca_HVA_GP VOLTAGE Vm addmsg GP_dendrite_p/Ca_HVA_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dendrite_p/K_ahp_GP addmsg GP_dendrite_p GP_dendrite_p/K_ahp_GP VOLTAGE Vm addmsg GP_dendrite_p/K_ahp_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/K_ahp_GP Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dendrite_p/Ca_GP_nernst copy Ca_GP_conc GP_dendrite_p/Ca_GP_conc addmsg GP_dendrite_p/Ca_HVA_GP GP_dendrite_p/Ca_GP_conc I_Ca Ik addmsg GP_dendrite_p/Ca_GP_conc GP_dendrite_p/Ca_HVA_GP CONCEN Ca addmsg GP_dendrite_p/Ca_GP_conc GP_dendrite_p/K_ahp_GP CONCEN Ca addmsg GP_dendrite_p/Ca_GP_conc GP_dendrite_p/Ca_GP_nernst CIN Ca addmsg GP_dendrite_p/Ca_GP_nernst GP_dendrite_p/Ca_HVA_GP EK E setfield GP_dendrite_p/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dendrite_p/Na_fast_GP addmsg GP_dendrite_p GP_dendrite_p/Na_fast_GP VOLTAGE Vm addmsg GP_dendrite_p/Na_fast_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Na_fast_GP Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dendrite_p/Na_slow_GP addmsg GP_dendrite_p GP_dendrite_p/Na_slow_GP VOLTAGE Vm addmsg GP_dendrite_p/Na_slow_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Na_slow_GP Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dendrite_p/Kv3_GP addmsg GP_dendrite_p GP_dendrite_p/Kv3_GP VOLTAGE Vm addmsg GP_dendrite_p/Kv3_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Kv3_GP Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dendrite_p/Kv2_GP addmsg GP_dendrite_p GP_dendrite_p/Kv2_GP VOLTAGE Vm addmsg GP_dendrite_p/Kv2_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Kv2_GP Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dendrite_p/Kv4_fast_GP addmsg GP_dendrite_p GP_dendrite_p/Kv4_fast_GP VOLTAGE Vm addmsg GP_dendrite_p/Kv4_fast_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Kv4_fast_GP Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}} copy Kv4_slow_GP GP_dendrite_p/Kv4_slow_GP addmsg GP_dendrite_p GP_dendrite_p/Kv4_slow_GP VOLTAGE Vm addmsg GP_dendrite_p/Kv4_slow_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/Kv4_slow_GP Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}} copy KCNQ_GP GP_dendrite_p/KCNQ_GP addmsg GP_dendrite_p GP_dendrite_p/KCNQ_GP VOLTAGE Vm addmsg GP_dendrite_p/KCNQ_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/KCNQ_GP Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dendrite_p/h_HCN_GP addmsg GP_dendrite_p GP_dendrite_p/h_HCN_GP VOLTAGE Vm addmsg GP_dendrite_p/h_HCN_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/h_HCN_GP Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dendrite_p/h_HCN2_GP addmsg GP_dendrite_p GP_dendrite_p/h_HCN2_GP VOLTAGE Vm addmsg GP_dendrite_p/h_HCN2_GP GP_dendrite_p CHANNEL Gk Ek setfield GP_dendrite_p/h_HCN2_GP Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // Dendritic prototype = dendrite_dend3_distal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend3_distal25compts})) create compartment GP_dend3_distal25compts end setfield GP_dend3_distal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend3_distal25compts dendrite copy Ca_HVA_GP GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend3_distal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend3_distal25compts/Ca_GP_conc addmsg GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts GP_dend3_distal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend3_distal25compts/Ca_GP_conc GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts CONCEN Ca addmsg GP_dend3_distal25compts/Ca_GP_conc GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts CONCEN Ca addmsg GP_dend3_distal25compts/Ca_GP_conc GP_dend3_distal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend3_distal25compts/Ca_GP_nernst GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts EK E setfield GP_dend3_distal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend3_distal25compts/Na_fast_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Na_fast_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Na_fast_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Na_fast_GP_dend3_distal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend3_distal25compts/Na_slow_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Na_slow_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Na_slow_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Na_slow_GP_dend3_distal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend3_distal25compts/Kv3_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Kv3_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Kv3_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Kv3_GP_dend3_distal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend3_distal25compts/Kv2_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Kv2_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Kv2_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Kv2_GP_dend3_distal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend3_distal25compts/Kv4_fast_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Kv4_fast_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Kv4_fast_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Kv4_fast_GP_dend3_distal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_distal_KV4F_mult}} copy Kv4_slow_GP GP_dend3_distal25compts/Kv4_slow_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/Kv4_slow_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/Kv4_slow_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/Kv4_slow_GP_dend3_distal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_distal_KV4S_mult}} copy KCNQ_GP GP_dend3_distal25compts/KCNQ_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/KCNQ_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/KCNQ_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/KCNQ_GP_dend3_distal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend3_distal25compts/h_HCN_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/h_HCN_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/h_HCN_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/h_HCN_GP_dend3_distal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend3_distal25compts/h_HCN2_GP_dend3_distal25compts addmsg GP_dend3_distal25compts GP_dend3_distal25compts/h_HCN2_GP_dend3_distal25compts VOLTAGE Vm addmsg GP_dend3_distal25compts/h_HCN2_GP_dend3_distal25compts GP_dend3_distal25compts CHANNEL Gk Ek setfield GP_dend3_distal25compts/h_HCN2_GP_dend3_distal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // for the distal 25 compts, diameter specification is unnecessary bc all are dia0 // scaling HVA: setfield GP_dend3_distal25compts/Ca_HVA_GP_dend3_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3.0*{dend3_distal_HVA_mult}} // scaling SK: setfield GP_dend3_distal25compts/K_ahp_GP_dend3_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_distal_SK_mult}} // Dendritic prototype = dendrite_dend3_mid25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend3_mid25compts})) create compartment GP_dend3_mid25compts end setfield GP_dend3_mid25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend3_mid25compts dendrite copy Ca_HVA_GP GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend3_mid25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend3_mid25compts/Ca_GP_conc addmsg GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts GP_dend3_mid25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend3_mid25compts/Ca_GP_conc GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts CONCEN Ca addmsg GP_dend3_mid25compts/Ca_GP_conc GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts CONCEN Ca addmsg GP_dend3_mid25compts/Ca_GP_conc GP_dend3_mid25compts/Ca_GP_nernst CIN Ca addmsg GP_dend3_mid25compts/Ca_GP_nernst GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts EK E setfield GP_dend3_mid25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend3_mid25compts/Na_fast_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Na_fast_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Na_fast_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Na_fast_GP_dend3_mid25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend3_mid25compts/Na_slow_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Na_slow_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Na_slow_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Na_slow_GP_dend3_mid25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend3_mid25compts/Kv3_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Kv3_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Kv3_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Kv3_GP_dend3_mid25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend3_mid25compts/Kv2_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Kv2_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Kv2_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Kv2_GP_dend3_mid25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend3_mid25compts/Kv4_fast_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Kv4_fast_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Kv4_fast_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Kv4_fast_GP_dend3_mid25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_mid_KV4F_mult}} copy Kv4_slow_GP GP_dend3_mid25compts/Kv4_slow_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/Kv4_slow_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/Kv4_slow_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/Kv4_slow_GP_dend3_mid25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_mid_KV4S_mult}} copy KCNQ_GP GP_dend3_mid25compts/KCNQ_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/KCNQ_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/KCNQ_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/KCNQ_GP_dend3_mid25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend3_mid25compts/h_HCN_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/h_HCN_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/h_HCN_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/h_HCN_GP_dend3_mid25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend3_mid25compts/h_HCN2_GP_dend3_mid25compts addmsg GP_dend3_mid25compts GP_dend3_mid25compts/h_HCN2_GP_dend3_mid25compts VOLTAGE Vm addmsg GP_dend3_mid25compts/h_HCN2_GP_dend3_mid25compts GP_dend3_mid25compts CHANNEL Gk Ek setfield GP_dend3_mid25compts/h_HCN2_GP_dend3_mid25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of mid dend3 compartments if (!({exists GP_dend3_mid25compts_dia1})) copy GP_dend3_mid25compts GP_dend3_mid25compts_dia1 end if (!({exists GP_dend3_mid25compts_dia2})) copy GP_dend3_mid25compts GP_dend3_mid25compts_dia2 end // scale HVA for mid dend3 compartments setfield GP_dend3_mid25compts/Ca_HVA_GP_dend3_mid25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend3_mid_HVA_mult}} setfield GP_dend3_mid25compts_dia1/Ca_HVA_GP_dend3_mid25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend3_mid_HVA_mult}} setfield GP_dend3_mid25compts_dia2/Ca_HVA_GP_dend3_mid25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend3_mid_HVA_mult}} // scaling SK: setfield GP_dend3_mid25compts/K_ahp_GP_dend3_mid25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_mid_SK_mult}} setfield GP_dend3_mid25compts_dia1/K_ahp_GP_dend3_mid25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_mid_SK_mult}} setfield GP_dend3_mid25compts_dia2/K_ahp_GP_dend3_mid25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_mid_SK_mult}} // Dendritic prototype = dendrite_dend3_proximal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend3_proximal25compts})) create compartment GP_dend3_proximal25compts end setfield GP_dend3_proximal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend3_proximal25compts dendrite copy Ca_HVA_GP GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend3_proximal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend3_proximal25compts/Ca_GP_conc addmsg GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts GP_dend3_proximal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend3_proximal25compts/Ca_GP_conc GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts CONCEN Ca addmsg GP_dend3_proximal25compts/Ca_GP_conc GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts CONCEN Ca addmsg GP_dend3_proximal25compts/Ca_GP_conc GP_dend3_proximal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend3_proximal25compts/Ca_GP_nernst GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts EK E setfield GP_dend3_proximal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend3_proximal25compts/Na_fast_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Na_fast_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Na_fast_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Na_fast_GP_dend3_proximal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend3_proximal25compts/Na_slow_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Na_slow_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Na_slow_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Na_slow_GP_dend3_proximal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend3_proximal25compts/Kv3_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Kv3_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Kv3_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Kv3_GP_dend3_proximal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend3_proximal25compts/Kv2_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Kv2_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Kv2_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Kv2_GP_dend3_proximal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend3_proximal25compts/Kv4_fast_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Kv4_fast_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Kv4_fast_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Kv4_fast_GP_dend3_proximal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_proximal_KV4F_mult}} copy Kv4_slow_GP GP_dend3_proximal25compts/Kv4_slow_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/Kv4_slow_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/Kv4_slow_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/Kv4_slow_GP_dend3_proximal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend3_proximal_KV4S_mult}} copy KCNQ_GP GP_dend3_proximal25compts/KCNQ_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/KCNQ_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/KCNQ_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/KCNQ_GP_dend3_proximal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend3_proximal25compts/h_HCN_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/h_HCN_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/h_HCN_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/h_HCN_GP_dend3_proximal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend3_proximal25compts/h_HCN2_GP_dend3_proximal25compts addmsg GP_dend3_proximal25compts GP_dend3_proximal25compts/h_HCN2_GP_dend3_proximal25compts VOLTAGE Vm addmsg GP_dend3_proximal25compts/h_HCN2_GP_dend3_proximal25compts GP_dend3_proximal25compts CHANNEL Gk Ek setfield GP_dend3_proximal25compts/h_HCN2_GP_dend3_proximal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of mid dend3 compartments if (!({exists GP_dend3_proximal25compts_dia1})) copy GP_dend3_proximal25compts GP_dend3_proximal25compts_dia1 end if (!({exists GP_dend3_proximal25compts_dia2})) copy GP_dend3_proximal25compts GP_dend3_proximal25compts_dia2 end // scale HVA for proximal dend3 compartments setfield GP_dend3_proximal25compts/Ca_HVA_GP_dend3_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend3_proximal_HVA_mult}} setfield GP_dend3_proximal25compts_dia1/Ca_HVA_GP_dend3_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend3_proximal_HVA_mult}} setfield GP_dend3_proximal25compts_dia2/Ca_HVA_GP_dend3_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend3_proximal_HVA_mult}} // scaling SK: setfield GP_dend3_proximal25compts/K_ahp_GP_dend3_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_proximal_SK_mult}} setfield GP_dend3_proximal25compts_dia1/K_ahp_GP_dend3_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_proximal_SK_mult}} setfield GP_dend3_proximal25compts_dia2/K_ahp_GP_dend3_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend3_proximal_SK_mult}} // Dendritic prototype = dendrite_dend2_distal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend2_distal25compts})) create compartment GP_dend2_distal25compts end setfield GP_dend2_distal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend2_distal25compts dendrite copy Ca_HVA_GP GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend2_distal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend2_distal25compts/Ca_GP_conc addmsg GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts GP_dend2_distal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend2_distal25compts/Ca_GP_conc GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts CONCEN Ca addmsg GP_dend2_distal25compts/Ca_GP_conc GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts CONCEN Ca addmsg GP_dend2_distal25compts/Ca_GP_conc GP_dend2_distal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend2_distal25compts/Ca_GP_nernst GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts EK E setfield GP_dend2_distal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend2_distal25compts/Na_fast_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Na_fast_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Na_fast_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Na_fast_GP_dend2_distal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend2_distal25compts/Na_slow_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Na_slow_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Na_slow_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Na_slow_GP_dend2_distal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend2_distal25compts/Kv3_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Kv3_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Kv3_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Kv3_GP_dend2_distal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend2_distal25compts/Kv2_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Kv2_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Kv2_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Kv2_GP_dend2_distal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend2_distal25compts/Kv4_fast_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Kv4_fast_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Kv4_fast_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Kv4_fast_GP_dend2_distal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend2_distal_KV4F_mult}} copy Kv4_slow_GP GP_dend2_distal25compts/Kv4_slow_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/Kv4_slow_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/Kv4_slow_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/Kv4_slow_GP_dend2_distal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend2_distal_KV4S_mult}} copy KCNQ_GP GP_dend2_distal25compts/KCNQ_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/KCNQ_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/KCNQ_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/KCNQ_GP_dend2_distal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend2_distal25compts/h_HCN_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/h_HCN_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/h_HCN_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/h_HCN_GP_dend2_distal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend2_distal25compts/h_HCN2_GP_dend2_distal25compts addmsg GP_dend2_distal25compts GP_dend2_distal25compts/h_HCN2_GP_dend2_distal25compts VOLTAGE Vm addmsg GP_dend2_distal25compts/h_HCN2_GP_dend2_distal25compts GP_dend2_distal25compts CHANNEL Gk Ek setfield GP_dend2_distal25compts/h_HCN2_GP_dend2_distal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of distal dend2 compartments if (!({exists GP_dend2_distal25compts_dia1})) copy GP_dend2_distal25compts GP_dend2_distal25compts_dia1 end if (!({exists GP_dend2_distal25compts_dia2})) copy GP_dend2_distal25compts GP_dend2_distal25compts_dia2 end // scale HVA for distal dend2 compartments setfield GP_dend2_distal25compts/Ca_HVA_GP_dend2_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend2_distal_HVA_mult}} setfield GP_dend2_distal25compts_dia1/Ca_HVA_GP_dend2_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend2_distal_HVA_mult}} setfield GP_dend2_distal25compts_dia2/Ca_HVA_GP_dend2_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend2_distal_HVA_mult}} // scaling SK: setfield GP_dend2_distal25compts/K_ahp_GP_dend2_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_distal_SK_mult}} setfield GP_dend2_distal25compts_dia1/K_ahp_GP_dend2_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_distal_SK_mult}} setfield GP_dend2_distal25compts_dia2/K_ahp_GP_dend2_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_distal_SK_mult}} // Dendritic prototype = dendrite_dend2_proximal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend2_proximal25compts})) create compartment GP_dend2_proximal25compts end setfield GP_dend2_proximal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend2_proximal25compts dendrite copy Ca_HVA_GP GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend2_proximal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend2_proximal25compts/Ca_GP_conc addmsg GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts GP_dend2_proximal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend2_proximal25compts/Ca_GP_conc GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts CONCEN Ca addmsg GP_dend2_proximal25compts/Ca_GP_conc GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts CONCEN Ca addmsg GP_dend2_proximal25compts/Ca_GP_conc GP_dend2_proximal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend2_proximal25compts/Ca_GP_nernst GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts EK E setfield GP_dend2_proximal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend2_proximal25compts/Na_fast_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Na_fast_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Na_fast_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Na_fast_GP_dend2_proximal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend2_proximal25compts/Na_slow_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Na_slow_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Na_slow_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Na_slow_GP_dend2_proximal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend2_proximal25compts/Kv3_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Kv3_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Kv3_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Kv3_GP_dend2_proximal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend2_proximal25compts/Kv2_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Kv2_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Kv2_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Kv2_GP_dend2_proximal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend2_proximal25compts/Kv4_fast_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Kv4_fast_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Kv4_fast_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Kv4_fast_GP_dend2_proximal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend2_proximal_KV4F_mult}} copy Kv4_slow_GP GP_dend2_proximal25compts/Kv4_slow_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/Kv4_slow_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/Kv4_slow_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/Kv4_slow_GP_dend2_proximal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend2_proximal_KV4S_mult}} copy KCNQ_GP GP_dend2_proximal25compts/KCNQ_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/KCNQ_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/KCNQ_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/KCNQ_GP_dend2_proximal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend2_proximal25compts/h_HCN_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/h_HCN_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/h_HCN_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/h_HCN_GP_dend2_proximal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend2_proximal25compts/h_HCN2_GP_dend2_proximal25compts addmsg GP_dend2_proximal25compts GP_dend2_proximal25compts/h_HCN2_GP_dend2_proximal25compts VOLTAGE Vm addmsg GP_dend2_proximal25compts/h_HCN2_GP_dend2_proximal25compts GP_dend2_proximal25compts CHANNEL Gk Ek setfield GP_dend2_proximal25compts/h_HCN2_GP_dend2_proximal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of proximal dend2 compartments if (!({exists GP_dend2_proximal25compts_dia1})) copy GP_dend2_proximal25compts GP_dend2_proximal25compts_dia1 end if (!({exists GP_dend2_proximal25compts_dia2})) copy GP_dend2_proximal25compts GP_dend2_proximal25compts_dia2 end // scale HVA for proximal dend2 compartments setfield GP_dend2_proximal25compts/Ca_HVA_GP_dend2_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend2_proximal_HVA_mult}} setfield GP_dend2_proximal25compts_dia1/Ca_HVA_GP_dend2_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend2_proximal_HVA_mult}} setfield GP_dend2_proximal25compts_dia2/Ca_HVA_GP_dend2_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend2_proximal_HVA_mult}} // scaling SK: setfield GP_dend2_proximal25compts/K_ahp_GP_dend2_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_proximal_SK_mult}} setfield GP_dend2_proximal25compts_dia1/K_ahp_GP_dend2_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_proximal_SK_mult}} setfield GP_dend2_proximal25compts_dia2/K_ahp_GP_dend2_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend2_proximal_SK_mult}} // Dendritic prototype = dendrite_dend1_distal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend1_distal25compts})) create compartment GP_dend1_distal25compts end setfield GP_dend1_distal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend1_distal25compts dendrite copy Ca_HVA_GP GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend1_distal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend1_distal25compts/Ca_GP_conc addmsg GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts GP_dend1_distal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend1_distal25compts/Ca_GP_conc GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts CONCEN Ca addmsg GP_dend1_distal25compts/Ca_GP_conc GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts CONCEN Ca addmsg GP_dend1_distal25compts/Ca_GP_conc GP_dend1_distal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend1_distal25compts/Ca_GP_nernst GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts EK E setfield GP_dend1_distal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend1_distal25compts/Na_fast_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Na_fast_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Na_fast_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Na_fast_GP_dend1_distal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend1_distal25compts/Na_slow_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Na_slow_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Na_slow_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Na_slow_GP_dend1_distal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend1_distal25compts/Kv3_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Kv3_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Kv3_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Kv3_GP_dend1_distal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend1_distal25compts/Kv2_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Kv2_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Kv2_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Kv2_GP_dend1_distal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend1_distal25compts/Kv4_fast_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Kv4_fast_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Kv4_fast_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Kv4_fast_GP_dend1_distal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend1_distal_KV4F_mult}} copy Kv4_slow_GP GP_dend1_distal25compts/Kv4_slow_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/Kv4_slow_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/Kv4_slow_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/Kv4_slow_GP_dend1_distal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend1_distal_KV4S_mult}} copy KCNQ_GP GP_dend1_distal25compts/KCNQ_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/KCNQ_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/KCNQ_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/KCNQ_GP_dend1_distal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend1_distal25compts/h_HCN_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/h_HCN_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/h_HCN_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/h_HCN_GP_dend1_distal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend1_distal25compts/h_HCN2_GP_dend1_distal25compts addmsg GP_dend1_distal25compts GP_dend1_distal25compts/h_HCN2_GP_dend1_distal25compts VOLTAGE Vm addmsg GP_dend1_distal25compts/h_HCN2_GP_dend1_distal25compts GP_dend1_distal25compts CHANNEL Gk Ek setfield GP_dend1_distal25compts/h_HCN2_GP_dend1_distal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of distal dend1 compartments if (!({exists GP_dend1_distal25compts_dia1})) copy GP_dend1_distal25compts GP_dend1_distal25compts_dia1 end if (!({exists GP_dend1_distal25compts_dia2})) copy GP_dend1_distal25compts GP_dend1_distal25compts_dia2 end // scale HVA for distal dend1 compartments setfield GP_dend1_distal25compts/Ca_HVA_GP_dend1_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend1_distal_HVA_mult}} setfield GP_dend1_distal25compts_dia1/Ca_HVA_GP_dend1_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend1_distal_HVA_mult}} setfield GP_dend1_distal25compts_dia2/Ca_HVA_GP_dend1_distal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend1_distal_HVA_mult}} // scaling SK: setfield GP_dend1_distal25compts/K_ahp_GP_dend1_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_distal_SK_mult}} setfield GP_dend1_distal25compts_dia1/K_ahp_GP_dend1_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_distal_SK_mult}} setfield GP_dend1_distal25compts_dia2/K_ahp_GP_dend1_distal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_distal_SK_mult}} // Dendritic prototype = dendrite_dend1_proximal25compts (dia0) len = 1 dia = 1 rad = {dia} / 2.0 surf = 2*{PI}*rad*{len} vol = {PI}*rad*rad*{len} if (dia > {{shell_thick}*2}) rad_core = rad - {shell_thick} core_vol = {PI}*rad_core*rad_core*{len} shell_vol = vol - core_vol else shell_vol = vol end if (!({exists GP_dend1_proximal25compts})) create compartment GP_dend1_proximal25compts end setfield GP_dend1_proximal25compts Cm {{CM}*surf} Ra {4.0*{RA}*{len}/({dia}*{dia}*{PI})} \ Em {ELEAK_sd} initVm {EREST_ACT} Rm {{RM_sd}/surf} inject 0.0 \ dia {dia} len {len} // Put shared channels in prototype dend1_proximal25compts dendrite copy Ca_HVA_GP GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}} copy K_ahp_GP GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}} copy Ca_GP_nernst GP_dend1_proximal25compts/Ca_GP_nernst copy Ca_GP_conc GP_dend1_proximal25compts/Ca_GP_conc addmsg GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts GP_dend1_proximal25compts/Ca_GP_conc I_Ca Ik addmsg GP_dend1_proximal25compts/Ca_GP_conc GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts CONCEN Ca addmsg GP_dend1_proximal25compts/Ca_GP_conc GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts CONCEN Ca addmsg GP_dend1_proximal25compts/Ca_GP_conc GP_dend1_proximal25compts/Ca_GP_nernst CIN Ca addmsg GP_dend1_proximal25compts/Ca_GP_nernst GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts EK E setfield GP_dend1_proximal25compts/Ca_GP_conc B {{B_Ca_GP_conc}/shell_vol} copy Na_fast_GP GP_dend1_proximal25compts/Na_fast_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Na_fast_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Na_fast_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Na_fast_GP_dend1_proximal25compts Gbar \ {{G_Na_fast_GP}*surf*{G_mult_NaF_dend}*{G_mult}} copy Na_slow_GP GP_dend1_proximal25compts/Na_slow_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Na_slow_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Na_slow_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Na_slow_GP_dend1_proximal25compts Gbar \ {{G_Na_slow_GP}*surf*{G_mult_NaS_dend}*{G_mult}} copy Kv3_GP GP_dend1_proximal25compts/Kv3_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Kv3_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Kv3_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Kv3_GP_dend1_proximal25compts Gbar \ {{G_Kv3_GP}*surf*{G_mult_KV3_dend}*{G_mult}} copy Kv2_GP GP_dend1_proximal25compts/Kv2_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Kv2_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Kv2_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Kv2_GP_dend1_proximal25compts Gbar \ {{G_Kv2_GP}*surf*{G_mult_KV2_dend}*{G_mult}} copy Kv4_fast_GP GP_dend1_proximal25compts/Kv4_fast_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Kv4_fast_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Kv4_fast_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Kv4_fast_GP_dend1_proximal25compts Gbar \ {{G_Kv4_fast_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend1_proximal_KV4F_mult}} copy Kv4_slow_GP GP_dend1_proximal25compts/Kv4_slow_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/Kv4_slow_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/Kv4_slow_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/Kv4_slow_GP_dend1_proximal25compts Gbar \ {{G_Kv4_slow_GP}*surf*{G_mult_KA_dend}*{G_mult}*{dend1_proximal_KV4S_mult}} copy KCNQ_GP GP_dend1_proximal25compts/KCNQ_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/KCNQ_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/KCNQ_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/KCNQ_GP_dend1_proximal25compts Gbar \ {{G_KCNQ_GP}*surf*{G_mult_KCNQ_dend}*{G_mult}} copy h_HCN_GP GP_dend1_proximal25compts/h_HCN_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/h_HCN_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/h_HCN_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/h_HCN_GP_dend1_proximal25compts Gbar \ {{G_h_HCN_GP}*surf*{G_mult_HCN_dend}*{G_mult}} copy h_HCN2_GP GP_dend1_proximal25compts/h_HCN2_GP_dend1_proximal25compts addmsg GP_dend1_proximal25compts GP_dend1_proximal25compts/h_HCN2_GP_dend1_proximal25compts VOLTAGE Vm addmsg GP_dend1_proximal25compts/h_HCN2_GP_dend1_proximal25compts GP_dend1_proximal25compts CHANNEL Gk Ek setfield GP_dend1_proximal25compts/h_HCN2_GP_dend1_proximal25compts Gbar \ {{G_h_HCN2_GP}*surf*{G_mult_HCN_dend}*{G_mult}} // make compartment prototypes for different diameters of proximal dend1 compartments if (!({exists GP_dend1_proximal25compts_dia1})) copy GP_dend1_proximal25compts GP_dend1_proximal25compts_dia1 end if (!({exists GP_dend1_proximal25compts_dia2})) copy GP_dend1_proximal25compts GP_dend1_proximal25compts_dia2 end // scale HVA for proximal dend1 compartments setfield GP_dend1_proximal25compts/Ca_HVA_GP_dend1_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3*{dend1_proximal_HVA_mult}} setfield GP_dend1_proximal25compts_dia1/Ca_HVA_GP_dend1_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5*{dend1_proximal_HVA_mult}} setfield GP_dend1_proximal25compts_dia2/Ca_HVA_GP_dend1_proximal25compts Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*{dend1_proximal_HVA_mult}} // scaling SK: setfield GP_dend1_proximal25compts/K_ahp_GP_dend1_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_proximal_SK_mult}} setfield GP_dend1_proximal25compts_dia1/K_ahp_GP_dend1_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_proximal_SK_mult}} setfield GP_dend1_proximal25compts_dia2/K_ahp_GP_dend1_proximal25compts Gbar \ {{G_K_ahp_GP}*surf*{G_mult_SK_dend}*{G_mult}*{dend1_proximal_SK_mult}} // Make the actual dendritic components based on the prototype. if (!({exists GP_dendrite_d0_dia2})) copy GP_dendrite_p GP_dendrite_d0_dia2 end if (!({exists GP_dendrite_d0_dia1})) copy GP_dendrite_p GP_dendrite_d0_dia1 end if (!({exists GP_dendrite_d0_dia0})) copy GP_dendrite_p GP_dendrite_d0_dia0 end if (!({exists GP_dendrite_d25_dia2})) copy GP_dendrite_p GP_dendrite_d25_dia2 end if (!({exists GP_dendrite_d25_dia1})) copy GP_dendrite_p GP_dendrite_d25_dia1 end if (!({exists GP_dendrite_d25_dia0})) copy GP_dendrite_p GP_dendrite_d25_dia0 end if (!({exists GP_dendrite_d50_dia2})) copy GP_dendrite_p GP_dendrite_d50_dia2 end if (!({exists GP_dendrite_d50_dia1})) copy GP_dendrite_p GP_dendrite_d50_dia1 end if (!({exists GP_dendrite_d50_dia0})) copy GP_dendrite_p GP_dendrite_d50_dia0 end if (!({exists GP_dendrite_d100_dia2})) copy GP_dendrite_p GP_dendrite_d100_dia2 end if (!({exists GP_dendrite_d100_dia1})) copy GP_dendrite_p GP_dendrite_d100_dia1 end if (!({exists GP_dendrite_d100_dia0})) copy GP_dendrite_p GP_dendrite_d100_dia0 end if (!({exists GP_dendrite_d200_dia2})) copy GP_dendrite_p GP_dendrite_d200_dia2 end if (!({exists GP_dendrite_d200_dia1})) copy GP_dendrite_p GP_dendrite_d200_dia1 end if (!({exists GP_dendrite_d200_dia0})) copy GP_dendrite_p GP_dendrite_d200_dia0 end if (!({exists GP_dendrite_d300_dia2})) copy GP_dendrite_p GP_dendrite_d300_dia2 end if (!({exists GP_dendrite_d300_dia1})) copy GP_dendrite_p GP_dendrite_d300_dia1 end if (!({exists GP_dendrite_d300_dia0})) copy GP_dendrite_p GP_dendrite_d300_dia0 end if (!({exists GP_dendrite_d400_dia2})) copy GP_dendrite_p GP_dendrite_d400_dia2 end if (!({exists GP_dendrite_d400_dia1})) copy GP_dendrite_p GP_dendrite_d400_dia1 end if (!({exists GP_dendrite_d400_dia0})) copy GP_dendrite_p GP_dendrite_d400_dia0 end if (!({exists GP_dendrite_d500_dia2})) copy GP_dendrite_p GP_dendrite_d500_dia2 end if (!({exists GP_dendrite_d500_dia1})) copy GP_dendrite_p GP_dendrite_d500_dia1 end if (!({exists GP_dendrite_d500_dia0})) copy GP_dendrite_p GP_dendrite_d500_dia0 end if (!({exists GP_dendrite_d600_dia2})) copy GP_dendrite_p GP_dendrite_d600_dia2 end if (!({exists GP_dendrite_d600_dia1})) copy GP_dendrite_p GP_dendrite_d600_dia1 end if (!({exists GP_dendrite_d600_dia0})) copy GP_dendrite_p GP_dendrite_d600_dia0 end if (!({exists GP_dendrite_d700_dia2})) copy GP_dendrite_p GP_dendrite_d700_dia2 end if (!({exists GP_dendrite_d700_dia1})) copy GP_dendrite_p GP_dendrite_d700_dia1 end if (!({exists GP_dendrite_d700_dia0})) copy GP_dendrite_p GP_dendrite_d700_dia0 end if (!({exists GP_dendrite_d800_dia2})) copy GP_dendrite_p GP_dendrite_d800_dia2 end if (!({exists GP_dendrite_d800_dia1})) copy GP_dendrite_p GP_dendrite_d800_dia1 end if (!({exists GP_dendrite_d800_dia0})) copy GP_dendrite_p GP_dendrite_d800_dia0 end if (!({exists GP_dendrite_d900_dia2})) copy GP_dendrite_p GP_dendrite_d900_dia2 end if (!({exists GP_dendrite_d900_dia1})) copy GP_dendrite_p GP_dendrite_d900_dia1 end if (!({exists GP_dendrite_d900_dia0})) copy GP_dendrite_p GP_dendrite_d900_dia0 end setfield GP_dendrite_d0_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d0_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d25_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d25_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d50_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d50_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d100_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d100_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d200_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d200_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d300_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d300_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d400_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d400_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d500_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d500_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d600_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d600_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d700_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d700_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d800_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d800_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} setfield GP_dendrite_d900_dia1/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*1.5} setfield GP_dendrite_d900_dia0/Ca_HVA_GP Gbar \ {{G_Ca_HVA_GP}*surf*{G_mult_Ca_dend}*{G_mult}*3} end