TITLE Mechanism internal calcium concentration cai
NEURON {
SUFFIX Cacon
USEION ca READ ica, cai WRITE cai
GLOBAL tauca, A, camin
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(molar) = (1/liter)
(mM) = (millimolar)
(uM) = (micromolar)
}
PARAMETER {
dt (ms)
tauca = 800 (ms)
: A = 1.03e-7 (mM cm2 / ms mA) : same as in paper
A = 0.2 :0.103
camin = 1e-8 (mM) : arbitrary
}
STATE {
cai (mM)
}
INITIAL {
cai = camin
}
ASSIGNED {
ica (mA/cm2)
}
BREAKPOINT {
SOLVE state METHOD cnexp
}
DERIVATIVE state {
cai' = -A*ica - (cai-camin)/tauca
}