strdef fitFile,timesFile,paramsFile,stimFile,outFile,modelFile,outFPre,base
objref st,stims,fin,fout,pmat,matOut,stimtime,somaref,secref,extVec,strFunc,most,root,transvec
ntimestep = 5000
nparams = 14
psize = 1
ntraces = 1
v_init = -70
calc_eca = 1
calc_eca = 1
stLoc = 0.5
base = "E:/GitHub/NeuroGPU/NeuroGPU_Base"
paramsFile = "./params/orig.csv"
stimFile = "./Stims/Stim_raw.csv"
modelFile = "./mosinit.hoc"
timesFile = "./Stims/times.csv"
transvec = new Vector(nparams)
fin = new File()
fout = new File()
load_file(modelFile)
root = new SectionRef()
if (root.has_parent()){
print secname()
root = root.root()
}
access cADpyr232_L5_TTPC1_0fb1ca4724[0].soma
create Exts[1]
objref recSites
recSites = new SectionList()
outFPre = "./volts/orig_step"
access root.sec
print "**********************"
print secname()
root.sec recSites.append()
secondorder=0
proc runMatrix(){
//access dend[1]
sprint(outFile,"%s_%s.dat",outFPre,secname())
st.del=0
st.dur=1e9
//printf ("$o1.nrow,$o2.nrow,$o2.ncol,%d,%d,%d",$o1.nrow,$o2.nrow,$o2.ncol)
matOut = new Matrix($o1.nrow,($o2.nrow*$o2.ncol))
for(sim=0;sim<$o1.nrow;sim+=1){
//printf("running sim %d\n",sim)
counter=0
transvec = $o1.getrow(sim)
tfunc()
for(i=0;i<stims.nrow;i+=1){
finitialize(v_init)
for(tt =0;tt<stimtime.ncol;tt+=1){
dt =stimtime.x(0,tt)
st.amp = 1*stims.x(i,tt)
matOut.x(sim,counter)=v(0.5)
counter+=1
fadvance()
}
}
}
//printf("finshed run matrix %s\n",outFile)
}
strFunc = new StringFunctions()
proc readMatrix(){localobj temp
csv_ind = strFunc.substr($s1,"csv")
if (csv_ind==-1){
temp = new Vector()
fin.ropen($s1)
for (i=0;i<$o2.nrow;i+=1){
temp.vread(fin)
$o2.setrow(i,temp)
//print i
}
fin.close()
} else {
readCSVMatrix($s1,$o2)
}
}
proc readCSVMatrix(){
fin = new File($s1)
fin.ropen()
print $o2.nrow()
$o2.scanf(fin,$o2.nrow(),$o2.ncol())
fin.close()
}
proc writeMatrix(){localobj temp
fout.wopen($s1)
temp = new Vector()
for (i=0;i<$o2.nrow;i+=1){
temp = $o2.getrow(i)
temp.vwrite(fout,3)
}
fout.close()
}
proc mul32(){localobj thisone
countSegs()
segsMat = segs+comps+1
//printf("1we have a matrix in the size of %d \n",segsMat )
segsToAdd = 32-segsMat%32
forall {
thisone = new SectionRef()
if (thisone.nchild == 0 ) {
break
}
}
access thisone.sec
nseg = nseg+segsToAdd
fcurrent()
countSegs()
//printf("we have a matrix in the size of %d \n",segs+comps+1 )
}
proc writeVector(){
fout.aopen($s1)
$o2.vwrite(fout,3)
fout.close()
}
proc printChildren(){localobj sl
sl = new SectionList()
sl.children()
u=0
forsec sl{
print secname()
u+=1
}
print u
}
proc printparent(){localobj sref
sref = new SectionRef()
sref.parent
print secname()
}
proc countSegs(){
segs=0
comps=0
forall{
segs+=nseg
comps+=1
}
}
create Exts[1]
proc hinesDisperseBranching(){local i localobj sl,secRef, clist, avec, bvec
counter = 0
forsec most{
secRef = new SectionRef()
if(secRef.nchild>2){
clist = new List()
for i=0, secRef.nchild-1 {
secRef.child[i] clist.append(new SectionRef())
}
Exts[counter]{
L = 1e-9
diam = 1
Ra = secRef.sec.Ra
cm = secRef.sec.cm
nseg = secRef.nchild-1
}
i=0
Exts[counter]{
for(x){
if (x > 0) {
avec =new Vector()
bvec =new Vector()
//printf("x is %f i is %d\n",x,i)
clist.o(i).sec{
avec =new Vector()
bvec =new Vector()
for(y){
avec.append(GetA(y))
bvec.append(GetB(y))
}
}
connect clist.o(i).sec(0), x
k=0
clist.o(i).sec{
for(y){
SetA(y,avec.x(k))
SetB(y,bvec.x(k))
}
}
i +=1
}
}
}
fcurrent()
secRef {
connect Exts[counter](0), 1
}
Exts[counter]{
for(x){
//printf("x is %f and sec is %s\n",x,secname())
SetA(x,0)
SetB(x,0)
}
}
counter+=1
}
}
//print "printing counter"
//print counter
}
proc countExts(){
ext_num=0
forsec most {
somaref= new SectionRef()
if (somaref.nchild>2){
ext_num+=1
}
}
//printf("ext_num is %d", ext_num)
}
proc PrintRecSites(){localobj sref
recSites.printnames()
}
stimtime = new Matrix(1,ntimestep)
readMatrix(timesFile,stimtime)
pmat = new Matrix(psize,nparams)
readMatrix(paramsFile,pmat)
stims = new Matrix(ntraces,ntimestep)
readCSVMatrix(stimFile,stims)
forsec "dend" nseg=1
forsec "apic" nseg=1
//topology()
most = new SectionList()
forall most.append()
countExts()
fcurrent()
//fmatrix()
//printf("Creating Exts %d\n",ext_num)
//printf("Creating Exts %d\n",ext_num)
if(ext_num>0){
create Exts[ext_num]
} else{
access Exts[0]
delete_section()
}
//****************************************************
forall{nseg=1}
//******************************************************
hinesDisperseBranching()
working()
mul32()
access root.sec
transvec = pmat.getrow(0)
tfunc()
st = new IClamp(0.5)
finitialize(v_init)
//runMatrix(pmat,stims)
//writeMatrix(outFile,matOut)
finitialize(v_init)
//ADD STUFF HERE
//quit()