TITLE H-current from cat sensorimotor cortex
COMMENT Equations from
Spain WJ, Schwindt PC, Crill WE (1987) Anomalous rectification in
neurons from cat sensorimotor cortex in vitro. J Neurophysiol 57(5):
1555-1576.
See also
Bernander O, Koch C, Douglas RJ (1994) Amplification and linearization
of distal synaptic input to cortical pyramidal cells. J Neurophysiol
72(6): 2743-2753.
Hutcheon B, Miura RM, Puil E (1996) Models of subthreshold membrane
resonance in neocortical neurons. J Neurophysiol 76(2): 698-714.
>< Time constants were measure at 36 degC.
>< Written by Arthur Houweling.
ENDCOMMENT
NEURON {
SUFFIX H
NONSPECIFIC_CURRENT i
RANGE g, i, hinf, h1tau, h2tau
}
UNITS {
(S) = (siemens)
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
e= -43 (mV)
g (S/cm2)
}
ASSIGNED {
v (mV)
i (mA/cm2)
h1tau (ms)
h2tau (ms)
hinf
}
STATE { h1 h2 }
BREAKPOINT {
SOLVE states METHOD cnexp
i= g* (0.8* h1+ 0.2* h2)* (v- e)
}
DERIVATIVE states {
rates()
h1'= (hinf- h1)/ h1tau
h2'= (hinf- h2)/ h2tau
}
INITIAL {
rates()
h1= hinf
h2= hinf
}
PROCEDURE rates() { UNITSOFF
hinf= 1/ (1+ exp((v+ 82)/ 7))
h1tau= 40
h2tau= 300
} UNITSON