COMMENT
calcium accumulation into a volume of area*depth next to the
membrane with a decay (time constant tau) to resting level
given by the global calcium variable cai0_ca_ion
ENDCOMMENT
NEURON {
SUFFIX cacum
USEION ca READ ica WRITE cai
RANGE depth, tau, cai0
}
UNITS {
(mM) = (milli/liter)
(mA) = (milliamp)
F = (faraday) (coulombs)
}
PARAMETER {
depth = 1 (nm) : assume volume = area*depth
tau = 10 (ms)
cai0 = 50e-6 (mM) : Requires explicit use in INITIAL
: block for it to take precedence over cai0_ca_ion
: Do not forget to initialize in hoc if different
: from this default.
}
ASSIGNED {
ica (mA/cm2)
}
STATE {
cai (mM)
}
INITIAL {
cai = cai0
}
BREAKPOINT {
SOLVE integrate METHOD derivimplicit
}
DERIVATIVE integrate {
cai' = -ica/depth/F/2 * (1e7) + (cai0 - cai)/tau
}