Model { Name "Facilitation" Version 6.3 MdlSubVersion 0 GraphicalInterface { NumRootInports 0 NumRootOutports 0 ParameterArgumentNames "" ComputedModelVersion "1.1009" NumModelReferences 0 NumTestPointedSignals 0 } Description "This is a model of depression in synapses\n\n" SavedCharacterEncoding "UTF-8" SaveDefaultBlockParams on SampleTimeColors off LibraryLinkDisplay "none" WideLines off ShowLineDimensions off ShowPortDataTypes off ShowLoopsOnError on IgnoreBidirectionalLines off ShowStorageClass off ShowTestPointIcons on ShowViewerIcons on SortedOrder off ExecutionContextIcon off ShowLinearizationAnnotations on RecordCoverage off CovPath "/" CovSaveName "covdata" CovMetricSettings "dw" CovNameIncrementing off CovHtmlReporting on covSaveCumulativeToWorkspaceVar on CovSaveSingleToWorkspaceVar on CovCumulativeVarName "covCumulativeData" CovCumulativeReport off CovReportOnPause on ScopeRefreshTime 0.035000 OverrideScopeRefreshTime on DisableAllScopes off DataTypeOverride "UseLocalSettings" MinMaxOverflowLogging "UseLocalSettings" MinMaxOverflowArchiveMode "Overwrite" BlockNameDataTip off BlockParametersDataTip off BlockDescriptionStringDataTip off ToolBar on StatusBar on BrowserShowLibraryLinks off BrowserLookUnderMasks off Created "Mon Oct 11 17:03:19 2004" Creator "chchlee" UpdateHistory "UpdateHistoryNever" ModifiedByFormat "%<Auto>" LastModifiedBy "Owner" ModifiedDateFormat "%<Auto>" LastModifiedDate "Sat Nov 01 14:27:35 2008" ModelVersionFormat "1.%<AutoIncrement:1009>" ConfigurationManager "None" LinearizationMsg "none" Profile off ParamWorkspaceSource "MATLABWorkspace" AccelSystemTargetFile "accel.tlc" AccelTemplateMakefile "accel_default_tmf" AccelMakeCommand "make_rtw" TryForcingSFcnDF off ExtModeBatchMode off ExtModeEnableFloating on ExtModeTrigType "manual" ExtModeTrigMode "normal" ExtModeTrigPort "1" ExtModeTrigElement "any" ExtModeTrigDuration 1000 ExtModeTrigDurationFloating "auto" ExtModeTrigHoldOff 0 ExtModeTrigDelay 0 ExtModeTrigDirection "rising" ExtModeTrigLevel 0 ExtModeArchiveMode "off" ExtModeAutoIncOneShot off ExtModeIncDirWhenArm off ExtModeAddSuffixToVar off ExtModeWriteAllDataToWs off ExtModeArmWhenConnect on ExtModeSkipDownloadWhenConnect off ExtModeLogAll on ExtModeAutoUpdateStatusClock off BufferReuse on StrictBusMsg "Warning" ProdHWDeviceType "32-bit Generic" ShowModelReferenceBlockVersion off ShowModelReferenceBlockIO off Array { Type "Handle" Dimension 1 Simulink.ConfigSet { $ObjectID 1 Version "1.1.0" Array { Type "Handle" Dimension 7 Simulink.SolverCC { $ObjectID 2 Version "1.1.0" StartTime "0" StopTime "300" AbsTol "auto" FixedStep "auto" InitialStep "auto" MaxNumMinSteps "-1" MaxOrder 5 ExtrapolationOrder 4 NumberNewtonIterations 1 MaxStep "0.01" MinStep "auto" RelTol "1e-3" SolverMode "Auto" Solver "ode23s" SolverName "ode23s" ZeroCrossControl "UseLocalSettings" AlgebraicLoopSolver "TrustRegion" SolverResetMethod "Fast" PositivePriorityOrder off AutoInsertRateTranBlk off SampleTimeConstraint "Unconstrained" RateTranMode "Deterministic" } Simulink.DataIOCC { $ObjectID 3 Version "1.1.0" Decimation "1" ExternalInput "[t, u]" FinalStateName "xFinal" InitialState "xInitial" LimitDataPoints on MaxDataPoints "1000" LoadExternalInput off LoadInitialState off SaveFinalState off SaveFormat "Array" SaveOutput on SaveState off SignalLogging on InspectSignalLogs off SaveTime on StateSaveName "xout" TimeSaveName "tout" OutputSaveName "yout" SignalLoggingName "sigsOut" OutputOption "RefineOutputTimes" OutputTimes "[]" Refine "1" } Simulink.OptimizationCC { $ObjectID 4 Version "1.1.0" BlockReduction on BooleanDataType on ConditionallyExecuteInputs on InlineParams off InlineInvariantSignals on OptimizeBlockIOStorage on BufferReuse on EnforceIntegerDowncast on ExpressionFolding on FoldNonRolledExpr on LocalBlockOutputs on ParameterPooling on RollThreshold 5 SystemCodeInlineAuto off StateBitsets off DataBitsets off UseTempVars off ZeroExternalMemoryAtStartup on ZeroInternalMemoryAtStartup on InitFltsAndDblsToZero on NoFixptDivByZeroProtection off EfficientFloat2IntCast off OptimizeModelRefInitCode off LifeSpan "inf" BufferReusableBoundary on } Simulink.DebuggingCC { $ObjectID 5 Version "1.1.0" RTPrefix "error" ConsistencyChecking "none" ArrayBoundsChecking "none" SignalInfNanChecking "none" ReadBeforeWriteMsg "UseLocalSettings" WriteAfterWriteMsg "UseLocalSettings" WriteAfterReadMsg "UseLocalSettings" AlgebraicLoopMsg "warning" ArtificialAlgebraicLoopMsg "warning" CheckSSInitialOutputMsg on CheckExecutionContextPreStartOutputMsg off CheckExecutionContextRuntimeOutputMsg off SignalResolutionControl "TryResolveAllWithWarning" BlockPriorityViolationMsg "warning" MinStepSizeMsg "warning" SolverPrmCheckMsg "none" InheritedTsInSrcMsg "warning" DiscreteInheritContinuousMsg "warning" MultiTaskDSMMsg "warning" MultiTaskRateTransMsg "error" SingleTaskRateTransMsg "none" TasksWithSamePriorityMsg "warning" SigSpecEnsureSampleTimeMsg "warning" CheckMatrixSingularityMsg "none" IntegerOverflowMsg "warning" Int32ToFloatConvMsg "warning" ParameterDowncastMsg "error" ParameterOverflowMsg "error" ParameterUnderflowMsg "none" ParameterPrecisionLossMsg "warning" UnderSpecifiedDataTypeMsg "none" UnnecessaryDatatypeConvMsg "none" VectorMatrixConversionMsg "none" InvalidFcnCallConnMsg "error" FcnCallInpInsideContextMsg "Use local settings" SignalLabelMismatchMsg "none" UnconnectedInputMsg "warning" UnconnectedOutputMsg "warning" UnconnectedLineMsg "warning" SFcnCompatibilityMsg "none" UniqueDataStoreMsg "none" BusObjectLabelMismatch "warning" RootOutportRequireBusObject "warning" AssertControl "UseLocalSettings" EnableOverflowDetection off ModelReferenceIOMsg "none" ModelReferenceVersionMismatchMessage "none" ModelReferenceIOMismatchMessage "none" ModelReferenceCSMismatchMessage "none" ModelReferenceSimTargetVerbose off UnknownTsInhSupMsg "warning" ModelReferenceDataLoggingMessage "warning" ModelReferenceSymbolNameMessage "warning" ModelReferenceExtraNoncontSigs "error" } Simulink.HardwareCC { $ObjectID 6 Version "1.1.0" ProdBitPerChar 8 ProdBitPerShort 16 ProdBitPerInt 32 ProdBitPerLong 32 ProdIntDivRoundTo "Undefined" ProdEndianess "Unspecified" ProdWordSize 32 ProdShiftRightIntArith on ProdHWDeviceType "32-bit Generic" TargetBitPerChar 8 TargetBitPerShort 16 TargetBitPerInt 32 TargetBitPerLong 32 TargetShiftRightIntArith on TargetIntDivRoundTo "Undefined" TargetEndianess "Unspecified" TargetWordSize 32 TargetTypeEmulationWarnSuppressLevel 0 TargetPreprocMaxBitsSint 32 TargetPreprocMaxBitsUint 32 TargetHWDeviceType "Specified" TargetUnknown on ProdEqTarget on } Simulink.ModelReferenceCC { $ObjectID 7 Version "1.1.0" UpdateModelReferenceTargets "IfOutOfDateOrStructuralChange" CheckModelReferenceTargetMessage "error" ModelReferenceNumInstancesAllowed "Multi" ModelReferencePassRootInputsByReference on ModelReferenceMinAlgLoopOccurrences off } Simulink.RTWCC { $BackupClass "Simulink.RTWCC" $ObjectID 8 Version "1.1.0" SystemTargetFile "grt.tlc" GenCodeOnly off MakeCommand "make_rtw" TemplateMakefile "grt_default_tmf" GenerateReport off SaveLog off RTWVerbose on RetainRTWFile off ProfileTLC off TLCDebug off TLCCoverage off TLCAssert off ProcessScriptMode "Default" ConfigurationMode "Optimized" ConfigAtBuild off IncludeHyperlinkInReport off LaunchReport off TargetLang "C" Array { Type "Handle" Dimension 2 Simulink.CodeAppCC { $ObjectID 9 Version "1.1.0" ForceParamTrailComments off GenerateComments on IgnoreCustomStorageClasses on IncHierarchyInIds off MaxIdLength 31 PreserveName off PreserveNameWithParent off ShowEliminatedStatement off IncAutoGenComments off SimulinkDataObjDesc off SFDataObjDesc off IncDataTypeInIds off PrefixModelToSubsysFcnNames on CustomSymbolStr "$R$N$M" MangleLength 1 DefineNamingRule "None" ParamNamingRule "None" SignalNamingRule "None" InsertBlockDesc off SimulinkBlockComments on EnableCustomComments off InlinedPrmAccess "Literals" ReqsInCode off } Simulink.GRTTargetCC { $BackupClass "Simulink.TargetCC" $ObjectID 10 Version "1.1.0" TargetFcnLib "ansi_tfl_tmw.mat" TargetLibSuffix "" TargetPreCompLibLocation "" GenFloatMathFcnCalls "ANSI_C" UtilityFuncGeneration "Auto" GenerateFullHeader on GenerateSampleERTMain off IsPILTarget off ModelReferenceCompliant off IncludeMdlTerminateFcn on CombineOutputUpdateFcns off SuppressErrorStatus off IncludeFileDelimiter "Auto" ERTCustomFileBanners off SupportAbsoluteTime on LogVarNameModifier "rt_" MatFileLogging off MultiInstanceERTCode off SupportNonFinite on SupportComplex on PurelyIntegerCode off SupportContinuousTime on SupportNonInlinedSFcns on ExtMode off ExtModeStaticAlloc off ExtModeTesting off ExtModeStaticAllocSize 1000000 ExtModeTransport 0 ExtModeMexFile "ext_comm" RTWCAPISignals off RTWCAPIParams off RTWCAPIStates off GenerateASAP2 off } PropName "Components" } } PropName "Components" } Name "Configuration" SimulationMode "normal" CurrentDlgPage "Solver" } PropName "ConfigurationSets" } Simulink.ConfigSet { $PropName "ActiveConfigurationSet" $ObjectID 1 } BlockDefaults { Orientation "right" ForegroundColor "black" BackgroundColor "white" DropShadow off NamePlacement "normal" FontName "Helvetica" FontSize 10 FontWeight "normal" FontAngle "normal" ShowName on } BlockParameterDefaults { Block { BlockType Demux Outputs "4" DisplayOption "none" BusSelectionMode off } Block { BlockType FromWorkspace VariableName "simulink_input" SampleTime "-1" Interpolate on ZeroCross off OutputAfterFinalValue "Extrapolation" } Block { BlockType Outport Port "1" UseBusObject off BusObject "BusObject" BusOutputAsStruct off PortDimensions "-1" SampleTime "-1" DataType "auto" OutDataType "sfix(16)" OutScaling "2^0" SignalType "auto" SamplingMode "auto" OutputWhenDisabled "held" InitialOutput "[]" } Block { BlockType Scope ModelBased off TickLabels "OneTimeTick" ZoomMode "on" Grid "on" TimeRange "auto" YMin "-5" YMax "5" SaveToWorkspace off SaveName "ScopeData" LimitDataPoints on MaxDataPoints "5000" Decimation "1" SampleInput off SampleTime "-1" } Block { BlockType Selector InputType "Vector" IndexMode "One-based" ElementSrc "Internal" Elements "1" RowSrc "Internal" Rows "1" ColumnSrc "Internal" Columns "1" InputPortWidth "-1" IndexIsStartValue off OutputPortSize "1" } Block { BlockType "S-Function" FunctionName "system" SFunctionModules "''" PortCounts "[]" } Block { BlockType SubSystem ShowPortLabels on Permissions "ReadWrite" PermitHierarchicalResolution "All" SystemSampleTime "-1" RTWFcnNameOpts "Auto" RTWFileNameOpts "Auto" SimViewingDevice off DataTypeOverride "UseLocalSettings" MinMaxOverflowLogging "UseLocalSettings" } Block { BlockType TransferFcn Numerator "[1]" Denominator "[1 2 1]" AbsoluteTolerance "auto" Realization "auto" } Block { BlockType TransportDelay DelayTime "1" InitialOutput "0" BufferSize "1024" FixedBuffer off TransDelayFeedthrough off PadeOrder "0" } } AnnotationDefaults { HorizontalAlignment "center" VerticalAlignment "middle" ForegroundColor "black" BackgroundColor "white" DropShadow off FontName "Helvetica" FontSize 10 FontWeight "normal" FontAngle "normal" } LineDefaults { FontName "Helvetica" FontSize 9 FontWeight "normal" FontAngle "normal" } System { Name "Facilitation" Location [114, 121, 853, 430] Open on ModelBrowserVisibility off ModelBrowserWidth 200 ScreenColor "white" PaperOrientation "landscape" PaperPositionMode "auto" PaperType "usletter" PaperUnits "inches" ZoomFactor "100" ReportName "simulink-default.rpt" Block { BlockType Scope Name "ICa" Ports [1] Position [235, 189, 265, 221] BackgroundColor "cyan" FontName "Arial" FontSize 14 Floating off Location [5, 48, 1029, 733] Open off NumInputPorts "1" ZoomMode "xonly" List { ListType AxesTitles axes1 "%<SignalLabel>" } YMin "-67.5" YMax "-63" SaveName "ScopeData3" DataFormat "StructureWithTime" LimitDataPoints off SampleTime "0" } Block { BlockType Scope Name "IEPSC" Ports [1] Position [655, 114, 685, 146] BackgroundColor "cyan" FontName "Arial" FontSize 14 Floating off Location [5, 85, 1021, 762] Open off NumInputPorts "1" ZoomMode "yonly" List { ListType AxesTitles axes1 "%<SignalLabel>" } YMin "-8e-007" YMax "0" SaveToWorkspace on SaveName "sim_facilitation" DataFormat "Array" LimitDataPoints off SampleTime "0" } Block { BlockType TransferFcn Name "Postsynaptic Transfer Fcn" Position [525, 111, 590, 149] FontName "Arial" FontSize 14 Numerator "[-1e-10/5.5]" Denominator "[5 1]" } Block { BlockType Selector Name "Selector" Ports [1, 1] Position [390, 111, 430, 149] FontName "Arial" FontSize 14 Elements "[4]" InputPortWidth "4" Port { PortNumber 1 Name "Glutamate" RTWStorageClass "Auto" DataLoggingNameMode "SignalName" } } Block { BlockType SubSystem Name "Stimulus_50Hz_ICa" Ports [0, 1] Position [70, 107, 165, 153] BackgroundColor "green" FontName "Arial" FontSize 14 TreatAsAtomicUnit off MinAlgLoopOccurrences off RTWSystemCode "Auto" MaskHideContents off System { Name "Stimulus_50Hz_ICa" Location [165, 128, 511, 247] Open off ModelBrowserVisibility off ModelBrowserWidth 200 ScreenColor "white" PaperOrientation "landscape" PaperPositionMode "auto" PaperType "usletter" PaperUnits "inches" ZoomFactor "100" Block { BlockType SubSystem Name "50 Hz, n=10 train" Tag "STV Subsys" Ports [0, 1] Position [25, 25, 120, 65] CopyFcn "sigbuilder_block('copy');" DeleteFcn "sigbuilder_block('delete');" LoadFcn "sigbuilder_block('load');" ModelCloseFcn "sigbuilder_block('modelClose');" PreSaveFcn "sigbuilder_block('preSave');" StartFcn "sigbuilder_block('start');" StopFcn "sigbuilder_block('stop');" NameChangeFcn "sigbuilder_block('namechange');" ClipboardFcn "sigbuilder_block('clipboard');" OpenFcn "sigbuilder_block('open',[-1.5 5.25 768 498 " "]);" CloseFcn "sigbuilder_block('close');" FontSize 14 TreatAsAtomicUnit off MinAlgLoopOccurrences off RTWSystemCode "Auto" MaskHideContents off MaskType "Sigbuilder block" MaskDescription "Sigbuilder GUI" MaskInitialization "if ~strcmp(get_param(bdroot(gcbh),'Simulati" "onStatus'),'stopped') tuvar = sigbuilder_block('maskInit'); end" MaskDisplay "plot(0,0,100,100,[10,10,40,40,10],[80,20,20" ",80,80],[40,10],[50,50], [40,27,10],[65,72,56],[40,25,25,10],[28,28,43,43]);" MaskIconFrame on MaskIconOpaque off MaskIconRotate "port" MaskIconUnits "autoscale" System { Name "50 Hz, n=10 train" Location [480, 85, 980, 386] Open off ModelBrowserVisibility off ModelBrowserWidth 200 ScreenColor "white" PaperOrientation "landscape" PaperPositionMode "auto" PaperType "usletter" PaperUnits "inches" ZoomFactor "100" Block { BlockType Demux Name "Demux" Tag "STV Demux" Ports [1, 1] Position [150, 30, 160, 600] Outputs "1" } Block { BlockType FromWorkspace Name "FromWs" Tag "STV FromWs" Position [30, 300, 115, 350] VariableName "tuvar" SampleTime "0" SigBuilderData "DataTag0" VnvData "DataTag1" } Block { BlockType Outport Name "Signal 1" Tag "STV Outport" Position [280, 30, 300, 40] IconDisplay "Port number" BusOutputAsStruct off } Line { SrcBlock "Demux" SrcPort 1 Points [50, 0; 0, -280] DstBlock "Signal 1" DstPort 1 } Line { SrcBlock "FromWs" SrcPort 1 Points [5, 0; 0, -10] DstBlock "Demux" DstPort 1 } } } Block { BlockType TransportDelay Name "Transport\nDelay" Position [165, 30, 195, 60] FontName "Arial" FontSize 14 DelayTime "11.5" BufferSize "2000" } Block { BlockType Outport Name "Out1" Position [280, 38, 310, 52] FontSize 14 IconDisplay "Port number" BusOutputAsStruct off } Line { SrcBlock "Transport\nDelay" SrcPort 1 DstBlock "Out1" DstPort 1 } Line { SrcBlock "50 Hz, n=10 train" SrcPort 1 DstBlock "Transport\nDelay" DstPort 1 } } } Block { BlockType "S-Function" Name "Vesicle trafficking model" Ports [1, 1] Position [235, 111, 360, 149] BackgroundColor "yellow" FontName "Arial" FontSize 14 FunctionName "facilitation_presyn" } Line { Name "Glutamate" FontName "Arial" FontSize 14 Labels [0, 0] SrcBlock "Selector" SrcPort 1 DstBlock "Postsynaptic Transfer Fcn" DstPort 1 } Line { SrcBlock "Vesicle trafficking model" SrcPort 1 DstBlock "Selector" DstPort 1 } Line { SrcBlock "Stimulus_50Hz_ICa" SrcPort 1 Points [0, 0; 25, 0] Branch { Points [0, 75] DstBlock "ICa" DstPort 1 } Branch { DstBlock "Vesicle trafficking model" DstPort 1 } } Line { SrcBlock "Postsynaptic Transfer Fcn" SrcPort 1 Points [0, 0] DstBlock "IEPSC" DstPort 1 } Annotation { Position [337, 576] UseDisplayTextAsClickCallback off } } } MatData { NumRecords 2 DataRecord { Tag DataTag1 Data " %)30 . 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