COMMENT
add CA dependence?
I_K.mod as K
Hodgkin-Huxley like potassium current as decribed in:
Terman D, Rubin JE, Yew AC, Wilson CJ (2002) Activity patterns in a model
for the subthalamopallidal network of the basal ganglia. J Neurosci 22:2963-76
ENDCOMMENT
NEURON {
SUFFIX K
NONSPECIFIC_CURRENT I
RANGE g0, v0, tau_0n, tau_1n, phi_n, theta_tn, theta_n, sigma_tn, sigma_n
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(S) = (siemens)
}
PARAMETER {
v (mV)
g0 (S/cm2)
v0 (mV)
phi_n
theta_tn
theta_n
sigma_tn
sigma_n
tau_0n (ms)
tau_1n (ms)
}
ASSIGNED {
I (mA/cm2)
n_inf
tau_n (ms)
}
STATE {
n
}
INITIAL {
rates(v)
n = n_inf
}
BREAKPOINT {
SOLVE states METHOD cnexp
I=g0*(n*n*n*n)*(v-v0)
}
DERIVATIVE states {
rates(v)
n' = phi_n*((n_inf-n)/tau_n)
}
PROCEDURE rates(v(mV)) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
UNITSOFF
tau_n = tau_0n + tau_1n/(1+exp(-(v-theta_tn)/sigma_tn))
n_inf = 1/(1+exp(-(v-theta_n)/sigma_n))
}
UNITSON