COMMENT
I_Na.mod as Na
Hodgkin-Huxley like sodium current as decribed in:
Terman D, Rubin JE, Yew AC, Wilson CJ (2002) Activity patterns in a model
for the subthalamopallidal network of the basal ganglia. J Neurosci 22:2963-76
ENDCOMMENT
NEURON {
SUFFIX Na
NONSPECIFIC_CURRENT I
RANGE g0, v0, tau_0h, tau_1h, phi_h, theta_th, theta_h, sigma_th, sigma_h, theta_m, sigma_m
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(S) = (siemens)
}
PARAMETER {
v (mV)
g0 (S/cm2)
v0 (mV)
phi_h
theta_th
theta_h
sigma_th
sigma_h
tau_0h (ms)
tau_1h (ms)
theta_m
sigma_m
}
ASSIGNED {
I (mA/cm2)
h_inf
tau_h (ms)
m_inf
}
STATE {
h
}
INITIAL {
rates(v)
h = h_inf
}
BREAKPOINT {
SOLVE states METHOD cnexp
I=g0*(m_inf*m_inf*m_inf)*h*(v-v0)
}
DERIVATIVE states {
rates(v)
h' = phi_h*((h_inf-h)/tau_h)
}
PROCEDURE rates(v(mV)) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
UNITSOFF
tau_h = tau_0h + tau_1h/(1+exp(-(v-theta_th)/sigma_th))
h_inf = 1/(1+exp(-(v-theta_h)/sigma_h))
m_inf = 1/(1+exp(-(v-theta_m)/sigma_m))
}
UNITSON