<?xml version="1.0" encoding="UTF-8"?> <sbml xmlns="http://www.sbml.org/sbml/level2/version3" metaid="metaid_0000001" level="2" version="3"> <model metaid="metaid_0000002" id="Model_1" name="Stefan2008_calmodulin_allostery"> <notes> <body xmlns="http://www.w3.org/1999/xhtml"> <p xmlns="http://www.w3.org/1999/xhtml">This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team. <br/>For more information see the <a href="http://www.ebi.ac.uk/biomodels/legal.html" target="_blank">terms of use</a>. <br/>To cite BioModels Database, please use <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16381960" target="_blank"> Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.</a> </p> </body> </notes> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000002"> <dc:creator rdf:parseType="Resource"> <rdf:Bag> <rdf:li rdf:parseType="Resource"> <vCard:N rdf:parseType="Resource"> <vCard:Family>Stefan</vCard:Family> <vCard:Given>Melanie</vCard:Given> </vCard:N> <vCard:EMAIL>mstefan@ebi.ac.uk</vCard:EMAIL> <vCard:ORG> <vCard:Orgname>EMBL-EBI</vCard:Orgname> </vCard:ORG> </rdf:li> <rdf:li rdf:parseType="Resource"> <vCard:N rdf:parseType="Resource"> <vCard:Family>Endler</vCard:Family> <vCard:Given>Lukas</vCard:Given> </vCard:N> <vCard:EMAIL>lukas@ebi.ac.uk</vCard:EMAIL> <vCard:ORG> <vCard:Orgname>EMBL-EBI</vCard:Orgname> </vCard:ORG> </rdf:li> </rdf:Bag> </dc:creator> <dcterms:created rdf:parseType="Resource"> <dcterms:W3CDTF>2008-07-15T14:18:02Z</dcterms:W3CDTF> </dcterms:created> <dcterms:modified rdf:parseType="Resource"> <dcterms:W3CDTF>2008-12-02T14:32:26Z</dcterms:W3CDTF> </dcterms:modified> <bqmodel:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:biomodels.db:BIOMD0000000183"/> </rdf:Bag> </bqmodel:is> <bqmodel:isDescribedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:pubmed:18669651"/> </rdf:Bag> </bqmodel:isDescribedBy> <bqbiol:occursIn> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:taxonomy:40674"/> </rdf:Bag> </bqbiol:occursIn> <bqbiol:isPartOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:kegg.pathway:ko04720"/> </rdf:Bag> </bqbiol:isPartOf> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005513"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> <listOfFunctionDefinitions> <functionDefinition metaid="metaid_0000003" id="function_1" name="function_4_Transition camT_ca1_A to camR_ca1_A"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> species_18 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_18 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <ci> parameter_11 </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000004" id="function_2" name="function_4_Transition camT_ca1_B to camR_ca1_B"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> species_19 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_19 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <ci> parameter_12 </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000005" id="function_5" name="function_4_Transition camR_ca2_AB to camT_ca2_AB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_6 </ci> </bvar> <apply> <times/> <ci> species_6 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000006" id="function_3" name="function_4_Transition camT_ca1_C to camR_ca1_C"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> species_20 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_20 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <ci> parameter_13 </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000007" id="function_6" name="function_4_Transition camR_ca2_AC to camT_ca2_AC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_7 </ci> </bvar> <apply> <times/> <ci> species_7 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000008" id="function_7" name="function_4_Transition camR_ca2_AD to camT_ca2_AD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_8 </ci> </bvar> <apply> <times/> <ci> species_8 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000009" id="function_4" name="function_4_Transition camT_ca1_D to camR_ca1_D"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_21 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_21 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <ci> parameter_14 </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000010" id="function_13" name="function_4_Transition camT_ca2_AD to camR_ca2_AD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_24 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_24 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000011" id="function_14" name="function_4_Transition camT_ca2_BC to camR_ca2_BC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> species_25 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_25 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000012" id="function_15" name="function_4_Transition camT_ca2_BD to camR_ca2_BD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_26 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_26 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000013" id="function_16" name="function_4_Transition camT_ca2_CD to camR_ca2_CD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_27 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_27 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000014" id="function_17" name="function_4_Transition camR_ca3_ABC to camT_ca3_ABC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_12 </ci> </bvar> <apply> <times/> <ci> species_12 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000015" id="function_18" name="function_4_Transition camR_ca3_ABD to camT_ca3_ABD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_13 </ci> </bvar> <apply> <times/> <ci> species_13 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000016" id="function_19" name="function_4_Transition camR_ca3_ACD to camT_ca3_ACD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_14 </ci> </bvar> <apply> <times/> <ci> species_14 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000017" id="function_20" name="function_4_Transition camR_ca3_BCD to camT_ca3_BCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_15 </ci> </bvar> <apply> <times/> <ci> species_15 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000018" id="function_8" name="function_4_Transition camR_ca2_BC to camT_ca2_BC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_9 </ci> </bvar> <apply> <times/> <ci> species_9 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000019" id="function_9" name="function_4_Transition camR_ca2_BD to camT_ca2_BD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_10 </ci> </bvar> <apply> <times/> <ci> species_10 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000020" id="function_10" name="function_4_Transition camR_ca2_CD to camT_ca2_CD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_11 </ci> </bvar> <apply> <times/> <ci> species_11 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000021" id="function_11" name="function_4_Transition camT_ca2_AB to camR_ca2_AB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> species_22 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_22 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000022" id="function_12" name="function_4_Transition camT_ca2_AC to camR_ca2_AC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> species_23 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_23 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000023" id="function_21" name="function_4_Transition camT_ca3_ABC to camR_ca3_ABC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> species_28 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_28 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000024" id="function_22" name="function_4_Transition camT_ca3_ABD to camR_ca3_ABD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_29 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_29 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000025" id="function_23" name="function_4_Transition camT_ca3_ACD to camR_ca3_ACD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_30 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_30 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000026" id="function_24" name="function_4_Transition camT_ca3_BCD to camR_ca3_BCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_31 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_31 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000027" id="function_25" name="function_4_Transition camR_ca4_ABCD to camT_ca4_ABCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> parameter_9 </ci> </bvar> <bvar> <ci> species_16 </ci> </bvar> <apply> <times/> <ci> species_16 </ci> <ci> parameter_9 </ci> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition metaid="metaid_0000028" id="function_26" name="function_4_Transition camT_ca4_ABCD to camR_ca4_ABCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> parameter_10 </ci> </bvar> <bvar> <ci> parameter_11 </ci> </bvar> <bvar> <ci> parameter_12 </ci> </bvar> <bvar> <ci> parameter_13 </ci> </bvar> <bvar> <ci> parameter_14 </ci> </bvar> <bvar> <ci> species_32 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_32 </ci> <ci> parameter_10 </ci> </apply> <apply> <power/> <apply> <times/> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> </listOfFunctionDefinitions> <listOfCompartments> <compartment metaid="metaid_0000090" id="compartment_0" name="Spine" size="1e-15"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000090"> <bqbiol:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0043197"/> </rdf:Bag> </bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </compartment> </listOfCompartments> <listOfSpecies> <species metaid="metaid_0000091" id="species_0" name="camR" compartment="compartment_0" initialConcentration="9.7e-12"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000091"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:isVersionOf> <bqbiol:isHomologTo> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:uniprot:P62158"/> </rdf:Bag> </bqbiol:isHomologTo> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000092" id="species_1" name="ca" compartment="compartment_0" initialConcentration="1e-05"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000092"> <bqbiol:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00076"/> </rdf:Bag> </bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000093" id="species_2" name="camR_ca1_A" compartment="compartment_0" initialConcentration="0"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000093"> <bqbiol:hasPart> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:hasPart> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000094" id="species_3" name="camR_ca1_B" compartment="compartment_0" initialConcentration="0"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000094"> <bqbiol:hasPart> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:hasPart> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000095" id="species_4" name="camR_ca1_C" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000096" id="species_5" name="camR_ca1_D" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000097" id="species_6" name="camR_ca2_AB" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000098" id="species_7" name="camR_ca2_AC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000099" id="species_8" name="camR_ca2_AD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000100" id="species_9" name="camR_ca2_BC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000101" id="species_10" name="camR_ca2_BD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000102" id="species_11" name="camR_ca2_CD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000103" id="species_12" name="camR_ca3_ABC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000104" id="species_13" name="camR_ca3_ABD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000105" id="species_14" name="camR_ca3_ACD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000106" id="species_15" name="camR_ca3_BCD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000107" id="species_16" name="camR_ca4_ABCD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000108" id="species_17" name="camT" compartment="compartment_0" initialConcentration="2e-07"/> <species metaid="metaid_0000109" id="species_18" name="camT_ca1_A" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000110" id="species_19" name="camT_ca1_B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000111" id="species_20" name="camT_ca1_C" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000112" id="species_21" name="camT_ca1_D" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000113" id="species_22" name="camT_ca2_AB" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000114" id="species_23" name="camT_ca2_AC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000115" id="species_24" name="camT_ca2_AD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000116" id="species_25" name="camT_ca2_BC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000117" id="species_26" name="camT_ca2_BD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000118" id="species_27" name="camT_ca2_CD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000119" id="species_28" name="camT_ca3_ABC" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000120" id="species_29" name="camT_ca3_ABD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000121" id="species_30" name="camT_ca3_ACD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000122" id="species_31" name="camT_ca3_BCD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000123" id="species_32" name="camT_ca4_ABCD" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000124" id="species_33" name="CaMKII" compartment="compartment_0" initialConcentration="7e-05"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000124"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:interpro:IPR015742"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000125" id="species_34" name="camR_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000126" id="species_35" name="camR_ca1_A_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000127" id="species_36" name="camR_ca1_B_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000128" id="species_37" name="camR_ca1_C_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000129" id="species_38" name="camR_ca1_D_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000130" id="species_39" name="camR_ca2_AB_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000131" id="species_40" name="camR_ca2_AC_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000132" id="species_41" name="camR_ca2_AD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000133" id="species_42" name="camR_ca2_BC_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000134" id="species_43" name="camR_ca2_BD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000135" id="species_44" name="camR_ca2_CD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000136" id="species_45" name="camR_ca3_ABC_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000137" id="species_46" name="camR_ca3_ABD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000138" id="species_47" name="camR_ca3_ACD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000139" id="species_48" name="camR_ca3_BCD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000140" id="species_49" name="camR_ca4_ABCD_CaMKII" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000141" id="species_50" name="PP2B" compartment="compartment_0" initialConcentration="1.6e-06"> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Description rdf:about="#metaid_0000141"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005955"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> </species> <species metaid="metaid_0000142" id="species_51" name="camR_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000143" id="species_52" name="camR_ca1_A_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000144" id="species_53" name="camR_ca1_B_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000145" id="species_54" name="camR_ca1_C_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000146" id="species_55" name="camR_ca1_D_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000147" id="species_56" name="camR_ca2_AB_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000148" id="species_57" name="camR_ca2_AC_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000149" id="species_58" name="camR_ca2_AD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000150" id="species_59" name="camR_ca2_BC_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000151" id="species_60" name="camR_ca2_BD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000152" id="species_61" name="camR_ca2_CD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000153" id="species_62" name="camR_ca3_ABC_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000154" id="species_63" name="camR_ca3_ABD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000155" id="species_64" name="camR_ca3_ACD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000156" id="species_65" name="camR_ca3_BCD_PP2B" compartment="compartment_0" initialConcentration="0"/> <species metaid="metaid_0000157" id="species_66" name="camR_ca4_ABCD_PP2B" compartment="compartment_0" initialConcentration="0"/> </listOfSpecies> <listOfParameters> <parameter metaid="metaid_0000029" id="parameter_0" name="kon" value="1000000"/> <parameter metaid="metaid_0000030" id="parameter_1" name="koffRA" value="8.32" constant="false"/> <parameter metaid="metaid_0000031" id="parameter_2" name="koffRB" value="0.0166" constant="false"/> <parameter metaid="metaid_0000032" id="parameter_3" name="koffRC" value="17.4" constant="false"/> <parameter metaid="metaid_0000033" id="parameter_4" name="koffRD" value="0.0145" constant="false"/> <parameter metaid="metaid_0000034" id="parameter_5" name="koffTA" value="2101.0101010101" constant="false"/> <parameter metaid="metaid_0000035" id="parameter_6" name="koffTB" value="4.19191919191919" constant="false"/> <parameter metaid="metaid_0000036" id="parameter_7" name="koffTC" value="4393.93939393939" constant="false"/> <parameter metaid="metaid_0000037" id="parameter_8" name="koffTD" value="3.66161616161616" constant="false"/> <parameter metaid="metaid_0000038" id="parameter_9" name="kRT" value="1000000"/> <parameter metaid="metaid_0000039" id="parameter_10" name="kTR" value="48.3792936623125" constant="false"/> <parameter metaid="metaid_0000040" id="parameter_11" name="cA" value="0.00396"/> <parameter metaid="metaid_0000041" id="parameter_12" name="cB" value="0.00396"/> <parameter metaid="metaid_0000042" id="parameter_13" name="cC" value="0.00396"/> <parameter metaid="metaid_0000043" id="parameter_14" name="cD" value="0.00396"/> <parameter metaid="metaid_0000044" id="parameter_15" name="konCaMKII" value="3200000"/> <parameter metaid="metaid_0000045" id="parameter_16" name="koffCaMKII" value="0.343"/> <parameter metaid="metaid_0000046" id="parameter_17" name="konPP2B" value="46000000"/> <parameter metaid="metaid_0000047" id="parameter_18" name="koffPP2B" value="0.0013"/> <parameter metaid="metaid_0000048" id="parameter_19" name="free_camR_ca3_total" value="0" constant="false"/> <parameter metaid="metaid_0000049" id="parameter_20" name="free_camT_ca3_total" value="0" constant="false"/> <parameter metaid="metaid_0000050" id="parameter_21" name="free_cam_ca3_total" value="0" constant="false"/> <parameter metaid="metaid_0000051" id="parameter_22" name="cam_ca4_total" value="0" constant="false"/> <parameter metaid="metaid_0000052" id="parameter_23" name="CaMKII_camR_ca1" value="0" constant="false"/> <parameter metaid="metaid_0000053" id="parameter_24" name="CaMKII_camR_ca2" value="0" constant="false"/> <parameter metaid="metaid_0000054" id="parameter_25" name="CaMKII_camR_ca3" value="0" constant="false"/> <parameter metaid="metaid_0000055" id="parameter_26" name="total_CaMKII_bound" value="0" constant="false"/> <parameter metaid="metaid_0000056" id="parameter_27" name="total CaMKII" value="7e-05" constant="false"/> <parameter metaid="metaid_0000057" id="parameter_28" name="CaMKIIbar" value="0" constant="false"/> <parameter metaid="metaid_0000058" id="parameter_29" name="PP2B_camR_ca1" value="0" constant="false"/> <parameter metaid="metaid_0000059" id="parameter_30" name="PP2B_camR_ca2" value="0" constant="false"/> <parameter metaid="metaid_0000060" id="parameter_31" name="PP2B_camR_ca3" value="0" constant="false"/> <parameter metaid="metaid_0000061" id="parameter_32" name="total_PP2B_bound" value="0" constant="false"/> <parameter metaid="metaid_0000062" id="parameter_33" name="total PP2B" value="1.6e-06" constant="false"/> <parameter metaid="metaid_0000063" id="parameter_34" name="PP2Bbar" value="0" constant="false"/> <parameter metaid="metaid_0000064" id="parameter_35" name="camR_unbound" value="9.7e-12" constant="false"/> <parameter metaid="metaid_0000065" id="parameter_36" name="total camR" value="9.7e-12" constant="false"/> <parameter metaid="metaid_0000066" id="parameter_37" name="total camT" value="2e-07" constant="false"/> <parameter metaid="metaid_0000067" id="parameter_38" name="Rbar" value="4.84976478640786e-05" constant="false"/> <parameter metaid="metaid_0000068" id="parameter_39" name="cam_ca3_total" value="0" constant="false"/> <parameter metaid="metaid_0000069" id="parameter_40" name="free_camR_ca2_total" value="0" constant="false"/> <parameter metaid="metaid_0000070" id="parameter_41" name="free_camT_ca2_total" value="0" constant="false"/> <parameter metaid="metaid_0000071" id="parameter_42" name="free_cam_ca2_total" value="0" constant="false"/> <parameter metaid="metaid_0000072" id="parameter_43" name="cam_ca2_total" value="0" constant="false"/> <parameter metaid="metaid_0000073" id="parameter_44" name="free_cam_ca1_total" value="0" constant="false"/> <parameter metaid="metaid_0000074" id="parameter_45" name="cam_ca1_total" value="0" constant="false"/> <parameter metaid="metaid_0000075" id="parameter_46" name="cam_ca0_total" value="2.000097e-07" constant="false"/> <parameter metaid="metaid_0000076" id="parameter_47" name="cam_total" value="2.000097e-07" constant="false"/> <parameter metaid="metaid_0000077" id="parameter_48" name="moles_bound_ca_per_moles_cam" value="0" constant="false"/> <parameter metaid="metaid_0000078" id="parameter_49" name="L" value="20670"/> <parameter metaid="metaid_0000079" id="parameter_50" name="KRA" value="8.32e-06"/> <parameter metaid="metaid_0000080" id="parameter_51" name="KRB" value="1.66e-08"/> <parameter metaid="metaid_0000081" id="parameter_52" name="KRC" value="1.74e-05"/> <parameter metaid="metaid_0000082" id="parameter_53" name="KRD" value="1.45e-08"/> <parameter metaid="metaid_0000083" id="parameter_54" name="alpha" constant="false"/> <parameter metaid="metaid_0000084" id="parameter_55" name="beta" constant="false"/> <parameter metaid="metaid_0000085" id="parameter_56" name="gamma" constant="false"/> <parameter metaid="metaid_0000086" id="parameter_57" name="delta" constant="false"/> <parameter metaid="metaid_0000087" id="parameter_58" name="epsilon" value="4.84976478640786e-05" constant="false"/> <parameter metaid="metaid_0000088" id="parameter_59" name="ybar" value="0" constant="false"/> <parameter metaid="metaid_0000089" id="parameter_60" name="ybar/(1-ybar)" value="0" constant="false"/> </listOfParameters> <listOfRules> <assignmentRule metaid="metaid_0000158" variable="parameter_1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> parameter_50 </ci> <ci> parameter_0 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000159" variable="parameter_20"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <plus/> <ci> species_28 </ci> <ci> species_29 </ci> <ci> species_30 </ci> <ci> species_31 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000160" variable="parameter_2"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> parameter_51 </ci> <ci> parameter_0 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000161" variable="parameter_3"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> parameter_52 </ci> <ci> parameter_0 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000162" variable="parameter_4"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> parameter_53 </ci> <ci> parameter_0 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000163" variable="parameter_5"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> parameter_1 </ci> <ci> parameter_11 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000164" variable="parameter_6"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> parameter_2 </ci> <ci> parameter_12 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000165" variable="parameter_7"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> parameter_3 </ci> <ci> parameter_13 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000166" variable="parameter_8"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> parameter_4 </ci> <ci> parameter_14 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000167" variable="parameter_10"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> parameter_9 </ci> <ci> parameter_49 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000168" variable="parameter_19"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <plus/> <ci> species_12 </ci> <ci> species_13 </ci> <ci> species_14 </ci> <ci> species_15 </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000169" 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id="reaction_28" name="Ca dissociating from camR_ca2_CD site D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_11"/> </listOfReactants> <listOfProducts> <speciesReference species="species_4"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_4 </ci> <ci> species_11 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000233" id="reaction_29" name="Ca dissociating from camR_ca2_AD site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_8"/> </listOfReactants> <listOfProducts> <speciesReference species="species_5"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_1 </ci> <ci> species_8 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000234" id="reaction_30" name="Ca dissociating from camR_ca2_BD site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_10"/> </listOfReactants> <listOfProducts> <speciesReference species="species_5"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_2 </ci> <ci> species_10 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000235" id="reaction_31" name="Ca dissociating from camR_ca2_CD site C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_11"/> </listOfReactants> <listOfProducts> <speciesReference species="species_5"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_3 </ci> <ci> species_11 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000236" id="reaction_32" name="Ca binding to camR_ca2_AB site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_6"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_12"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_6 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000237" id="reaction_33" name="Ca binding to camR_ca2_AB site D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_6"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_13"/> </listOfProducts> <kineticLaw> <math 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reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_9"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_15"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_9 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000244" id="reaction_40" name="Ca binding to camR_ca2_BD site A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_10"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_13"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_10 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000245" id="reaction_41" name="Ca binding to camR_ca2_BD site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_10"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_15"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_10 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000246" id="reaction_42" name="Ca binding to camR_ca2_CD site A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_11"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_14"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_11 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000247" id="reaction_43" name="Ca binding to camR_ca2_CD site B " reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_11"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_15"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_11 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000248" id="reaction_44" name="Ca dissociating from camR_ca3_ABC site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_12"/> </listOfReactants> <listOfProducts> <speciesReference species="species_9"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math 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<apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_18 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000277" id="reaction_73" name="Ca binding to camT_ca1_A site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_18"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_23"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_18 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000278" id="reaction_74" name="Ca binding to camT_ca1_A site D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_18"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_24"/> 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<apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_21 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000288" id="reaction_84" name="Ca dissociating from camT_ca2_AB site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_22"/> </listOfReactants> <listOfProducts> <speciesReference species="species_19"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_5 </ci> <ci> species_22 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000289" id="reaction_85" name="Ca dissociating from camT_ca2_AB site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_22"/> </listOfReactants> <listOfProducts> <speciesReference species="species_18"/> <speciesReference species="species_1"/> 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<kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_10 </ci> <ci> species_17 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000333" id="reaction_129" name="Transition camR_ca1_A to camT_ca1_A" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_2"/> </listOfReactants> <listOfProducts> <speciesReference species="species_18"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_9 </ci> <ci> species_2 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000334" id="reaction_130" name="Transition camR_ca1_B to camT_ca1_B" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_3"/> </listOfReactants> <listOfProducts> <speciesReference species="species_19"/> </listOfProducts> <kineticLaw> <math 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parameter_9 </ci> <ci> species_8 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000344" id="reaction_140" name="Transition camR_ca2_BC to camT_ca2_BC" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_9"/> </listOfReactants> <listOfProducts> <speciesReference species="species_25"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_8 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_9 </ci> <ci> species_9 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000345" id="reaction_141" name="Transition camR_ca2_BD to camT_ca2_BD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_10"/> </listOfReactants> <listOfProducts> <speciesReference species="species_26"/> </listOfProducts> <kineticLaw> <math 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<speciesReference species="species_22"/> </listOfReactants> <listOfProducts> <speciesReference species="species_6"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_11 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> species_22 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000348" id="reaction_144" name="Transition camT_ca2_AC to camR_ca2_AC" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_23"/> </listOfReactants> <listOfProducts> <speciesReference species="species_7"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_12 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_13 </ci> <ci> species_23 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000349" id="reaction_145" name="Transition camT_ca2_AD to camR_ca2_AD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_24"/> </listOfReactants> <listOfProducts> <speciesReference species="species_8"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_13 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_14 </ci> <ci> species_24 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000350" id="reaction_146" name="Transition camT_ca2_BC to camR_ca2_BC" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_25"/> </listOfReactants> <listOfProducts> <speciesReference species="species_9"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_14 </ci> <ci> parameter_10 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> species_25 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000351" id="reaction_147" name="Transition camT_ca2_BD to camR_ca2_BD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_26"/> </listOfReactants> <listOfProducts> <speciesReference species="species_10"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_15 </ci> <ci> parameter_10 </ci> <ci> parameter_12 </ci> <ci> parameter_14 </ci> <ci> species_26 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000352" id="reaction_148" name="Transition camT_ca2_CD to camR_ca2_CD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_27"/> </listOfReactants> <listOfProducts> <speciesReference species="species_11"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_16 </ci> <ci> parameter_10 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> species_27 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000353" id="reaction_149" name="Transition camR_ca3_ABC to camT_ca3_ABC" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_12"/> </listOfReactants> <listOfProducts> <speciesReference species="species_28"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_17 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_9 </ci> <ci> species_12 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000354" id="reaction_150" name="Transition camR_ca3_ABD to camT_ca3_ABD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_13"/> </listOfReactants> <listOfProducts> <speciesReference species="species_29"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_18 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_14 </ci> <ci> parameter_9 </ci> <ci> species_13 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000355" id="reaction_151" name="Transition camR_ca3_ACD to camT_ca3_ACD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_14"/> </listOfReactants> <listOfProducts> <speciesReference species="species_30"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_19 </ci> <ci> parameter_11 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> parameter_9 </ci> <ci> species_14 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000356" id="reaction_152" name="Transition camR_ca3_BCD to camT_ca3_BCD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_15"/> </listOfReactants> <listOfProducts> <speciesReference species="species_31"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_20 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> parameter_9 </ci> <ci> species_15 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000357" id="reaction_153" name="Transition camT_ca3_ABC to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_28"/> </listOfReactants> <listOfProducts> <speciesReference species="species_12"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_21 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> species_28 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000358" id="reaction_154" name="Transition camT_ca3_ABD to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_29"/> </listOfReactants> <listOfProducts> <speciesReference species="species_13"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_22 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_14 </ci> <ci> species_29 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000359" id="reaction_155" name="Transition camT_ca3_ACD to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_30"/> </listOfReactants> <listOfProducts> <speciesReference species="species_14"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_23 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> species_30 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000360" id="reaction_156" name="Transition camT_ca3_BCD to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_31"/> </listOfReactants> <listOfProducts> <speciesReference species="species_15"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_24 </ci> <ci> parameter_10 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> species_31 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000361" id="reaction_157" name="Transition camR_ca4_ABCD to camT_ca4_ABCD" reversible="false" sboTerm="SBO:0000181"> <listOfReactants> <speciesReference species="species_16"/> </listOfReactants> <listOfProducts> <speciesReference species="species_32"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_25 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> parameter_9 </ci> <ci> species_16 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000362" id="reaction_158" name="Transition camT_ca4_ABCD to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_32"/> </listOfReactants> <listOfProducts> <speciesReference species="species_16"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <apply> <ci> function_26 </ci> <ci> parameter_10 </ci> <ci> parameter_11 </ci> <ci> parameter_12 </ci> <ci> parameter_13 </ci> <ci> parameter_14 </ci> <ci> species_32 </ci> </apply> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000363" id="reaction_159" name="CaMKII binding to camR" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_0"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_34"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_0 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000364" id="reaction_160" name="CaMKII binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_2"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_35"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_2 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000365" id="reaction_161" name="CaMKII binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_3"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_36"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_3 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000366" id="reaction_162" name="CaMKII binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_4"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_37"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_4 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000367" id="reaction_163" name="CaMKII binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_5"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_38"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_5 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000368" id="reaction_164" name="CaMKII binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_6"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_39"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_6 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000369" id="reaction_165" name="CaMKII binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_7"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_40"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_7 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000370" id="reaction_166" name="CaMKII binding to camR_ca2_AD" reversible="false"> <listOfReactants> <speciesReference species="species_8"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_41"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_8 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000371" id="reaction_167" name="CaMKII binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_9"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_42"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_9 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000372" id="reaction_168" name="CaMKII binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_10"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_43"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_10 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000373" id="reaction_169" name="CaMKII binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_11"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_44"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_11 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000374" id="reaction_170" name="CaMKII binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_12"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_45"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_12 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000375" id="reaction_171" name="CaMKII binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_13"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_46"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_13 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000376" id="reaction_172" name="CaMKII binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_14"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_47"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_14 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000377" id="reaction_173" name="CaMKII binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_15"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_48"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_15 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000378" id="reaction_174" name="CaMKII binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_16"/> <speciesReference species="species_33"/> </listOfReactants> <listOfProducts> <speciesReference species="species_49"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_15 </ci> <ci> species_16 </ci> <ci> species_33 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000379" id="reaction_175" name="CaMKII dissociation from camR" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_34"/> </listOfReactants> <listOfProducts> <speciesReference species="species_0"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_34 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000380" id="reaction_176" name="CaMKII dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_35"/> </listOfReactants> <listOfProducts> <speciesReference species="species_2"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_35 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000381" id="reaction_177" name="CaMKII dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_36"/> </listOfReactants> <listOfProducts> <speciesReference species="species_3"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_36 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000382" id="reaction_178" name="CaMKII dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_37"/> </listOfReactants> <listOfProducts> <speciesReference species="species_4"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_37 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000383" id="reaction_179" name="CaMKII dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_38"/> </listOfReactants> <listOfProducts> <speciesReference species="species_5"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_38 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000384" id="reaction_180" name="CaMKII dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_39"/> </listOfReactants> <listOfProducts> <speciesReference species="species_6"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_39 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000385" id="reaction_181" name="CaMKII dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_40"/> </listOfReactants> <listOfProducts> <speciesReference species="species_7"/> <speciesReference species="species_33"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_16 </ci> <ci> species_40 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000386" id="reaction_182" name="CaMKII dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_41"/> </listOfReactants> <listOfProducts> 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</ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000396" id="reaction_192" name="PP2B binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_2"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_52"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_2 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000397" id="reaction_193" name="PP2B binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_3"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_53"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_3 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000398" id="reaction_194" name="PP2B binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_4"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_54"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_4 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000399" id="reaction_195" name="PP2B binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_5"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_55"/> 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</kineticLaw> </reaction> <reaction metaid="metaid_0000407" id="reaction_203" name="PP2B binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_13"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_63"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_13 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000408" id="reaction_204" name="PP2B binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_14"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_64"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_14 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000409" id="reaction_205" name="PP2B binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_15"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_65"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_17 </ci> <ci> species_15 </ci> <ci> species_50 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000410" id="reaction_206" name="PP2B binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_16"/> <speciesReference species="species_50"/> </listOfReactants> <listOfProducts> <speciesReference species="species_66"/> </listOfProducts> <kineticLaw> <math 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<speciesReference species="species_50"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_18 </ci> <ci> species_52 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000413" id="reaction_209" name="PP2B dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_53"/> </listOfReactants> <listOfProducts> <speciesReference species="species_3"/> <speciesReference species="species_50"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_18 </ci> <ci> species_53 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000414" id="reaction_210" name="PP2B dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_54"/> </listOfReactants> 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id="reaction_216" name="PP2B dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_60"/> </listOfReactants> <listOfProducts> <speciesReference species="species_10"/> <speciesReference species="species_50"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_18 </ci> <ci> species_60 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000421" id="reaction_217" name="PP2B dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_61"/> </listOfReactants> <listOfProducts> <speciesReference species="species_11"/> <speciesReference species="species_50"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_18 </ci> <ci> species_61 </ci> </apply> </math> 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<apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_35 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000437" id="reaction_233" name="Ca binding to camR_ca1_B_CaMKII site A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_36"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_39"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_36 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000438" id="reaction_234" name="Ca binding to camR_ca1_B_CaMKII site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_36"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference 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compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_38 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000446" id="reaction_242" name="Ca dissociation from camR_ca2_AB_CaMKII site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_39"/> </listOfReactants> <listOfProducts> <speciesReference species="species_36"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_1 </ci> <ci> species_39 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000447" id="reaction_243" name="Ca dissociation from camR_ca2_AB_CaMKII site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_39"/> </listOfReactants> <listOfProducts> <speciesReference species="species_35"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_2 </ci> <ci> species_39 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000448" id="reaction_244" name="Ca dissociation from camR_ca2_AC_CaMKII site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_40"/> </listOfReactants> <listOfProducts> <speciesReference species="species_37"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_1 </ci> <ci> species_40 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000449" id="reaction_245" name="Ca dissociation from camR_ca2_AC_CaMKII site C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_40"/> </listOfReactants> <listOfProducts> 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species_44 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000457" id="reaction_253" name="Ca dissociation from camR_ca2_CD_CaMKII site D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_44"/> </listOfReactants> <listOfProducts> <speciesReference species="species_37"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_4 </ci> <ci> species_44 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000458" id="reaction_254" name="Ca binding to camR_ca2_AB_CaMKII site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_39"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_45"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_39 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000459" id="reaction_255" name="Ca binding to camR_ca2_AB_CaMKII site D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_39"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_46"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_39 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000460" id="reaction_256" name="Ca binding to camR_ca2_AC_CaMKII site B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_40"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference 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<ci> parameter_0 </ci> <ci> species_62 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000547" id="reaction_343" name="Ca binding to camR_ca3_ABD_PP2B site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_63"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_66"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_63 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000548" id="reaction_344" name="Ca binding to camR_ca3_ACD_PP2B site B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_64"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_66"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_64 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000549" id="reaction_345" name="Ca binding to camR_ca3_BCD_PP2B site A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="species_65"/> <speciesReference species="species_1"/> </listOfReactants> <listOfProducts> <speciesReference species="species_66"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_0 </ci> <ci> species_65 </ci> <ci> species_1 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000550" id="reaction_346" name="Ca dissociating from camR_ca4_ABCD_PP2B site A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_66"/> </listOfReactants> <listOfProducts> <speciesReference species="species_65"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_1 </ci> <ci> species_66 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000551" id="reaction_347" name="Ca dissociating from camR_ca4_ABCD_PP2B site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_66"/> </listOfReactants> <listOfProducts> <speciesReference species="species_64"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_2 </ci> <ci> species_66 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000552" id="reaction_348" name="Ca dissociating from camR_ca4_ABCD_PP2B site C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_66"/> </listOfReactants> <listOfProducts> <speciesReference species="species_63"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_3 </ci> <ci> species_66 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000553" id="reaction_349" name="Ca dissociating from camR_ca4_ABCD_PP2B site D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_66"/> </listOfReactants> <listOfProducts> <speciesReference species="species_62"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_4 </ci> <ci> species_66 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000554" id="reaction_350" name="Ca dissociation from camR_ca1_CaMKII site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_36"/> </listOfReactants> <listOfProducts> <speciesReference species="species_34"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_2 </ci> <ci> species_36 </ci> </apply> </math> </kineticLaw> </reaction> <reaction metaid="metaid_0000555" id="reaction_351" name="Ca dissociating from camT_ca3_ABC site C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="species_28"/> </listOfReactants> <listOfProducts> <speciesReference species="species_22"/> <speciesReference species="species_1"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> compartment_0 </ci> <ci> parameter_7 </ci> <ci> species_28 </ci> </apply> </math> </kineticLaw> </reaction> </listOfReactions> </model> </sbml>