<?xml version="1.0" encoding="UTF-8" standalone="no"?> <sbml xmlns="http://www.sbml.org/sbml/level2/version3" level="2" metaid="metaid_0000001" version="3"> <model id="Model_1" metaid="metaid_0000002" name="Stefan2008_calmodulin_allostery"> <notes> <body xmlns="http://www.w3.org/1999/xhtml"> <p>This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team. <br/>For more information see the <a href="http://www.ebi.ac.uk/biomodels/legal.html" target="_blank">terms of use</a>. <br/>To cite BioModels Database, please use <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16381960" target="_blank"> Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.</a> </p> </body> </notes> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000002"> <dc:creator rdf:parseType="Resource"> <rdf:Bag> <rdf:li rdf:parseType="Resource"> <vCard:N rdf:parseType="Resource"> <vCard:Family>Stefan</vCard:Family> <vCard:Given>Melanie</vCard:Given> </vCard:N> <vCard:EMAIL>mstefan@ebi.ac.uk</vCard:EMAIL> <vCard:ORG> <vCard:Orgname>EMBL-EBI</vCard:Orgname> </vCard:ORG> </rdf:li> <rdf:li rdf:parseType="Resource"> <vCard:N rdf:parseType="Resource"> <vCard:Family>Endler</vCard:Family> <vCard:Given>Lukas</vCard:Given> </vCard:N> <vCard:EMAIL>lukas@ebi.ac.uk</vCard:EMAIL> <vCard:ORG> <vCard:Orgname>EMBL-EBI</vCard:Orgname> </vCard:ORG> </rdf:li> </rdf:Bag> </dc:creator> <dcterms:created rdf:parseType="Resource"> <dcterms:W3CDTF>2009-02-09T18:45:50+00:00</dcterms:W3CDTF> </dcterms:created> <dcterms:modified rdf:parseType="Resource"> <dcterms:W3CDTF>2009-02-10T09:24:03+00:00</dcterms:W3CDTF> </dcterms:modified> <bqmodel:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:biomodels.db:BIOMD0000000183"/> </rdf:Bag> </bqmodel:is> <bqmodel:isDescribedBy> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:pubmed:18669651"/> </rdf:Bag> </bqmodel:isDescribedBy> <bqbiol:occursIn> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:taxonomy:40674"/> </rdf:Bag> </bqbiol:occursIn> <bqbiol:isPartOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:kegg.pathway:ko04720"/> </rdf:Bag> </bqbiol:isPartOf> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005513"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> <listOfFunctionDefinitions> <functionDefinition id="function_1" metaid="metaid_0000003" name="function_4_Transition camT_ca1_A to camR_ca1_A"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> species_v_18 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_18 </ci> <ci> kTR </ci> </apply> <apply> <power/> <ci> cA </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_2" metaid="metaid_0000004" name="function_4_Transition camT_ca1_B to camR_ca1_B"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> species_v_19 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_19 </ci> <ci> kTR </ci> </apply> <apply> <power/> <ci> cB </ci> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_5" metaid="metaid_0000005" name="function_4_Transition camR_ca2_AB to camT_ca2_AB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_6 </ci> </bvar> <apply> <times/> <ci> species_v_6 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_3" metaid="metaid_0000006" name="function_4_Transition camT_ca1_C to camR_ca1_C"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> species_v_20 </ci> </bvar> <apply> <divide/> <apply> <times/> 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<bvar> <ci> cD </ci> </bvar> <bvar> <ci> species_v_24 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_24 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_14" metaid="metaid_0000011" name="function_4_Transition camT_ca2_BC to camR_ca2_BC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> species_v_25 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_25 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cB </ci> <ci> cC </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_15" metaid="metaid_0000012" name="function_4_Transition 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</apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_17" metaid="metaid_0000014" name="function_4_Transition camR_ca3_ABC to camT_ca3_ABC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_12 </ci> </bvar> <apply> <times/> <ci> species_v_12 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cC </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_18" metaid="metaid_0000015" name="function_4_Transition camR_ca3_ABD to camT_ca3_ABD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_13 </ci> </bvar> <apply> <times/> <ci> species_v_13 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_19" metaid="metaid_0000016" name="function_4_Transition camR_ca3_ACD to camT_ca3_ACD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_14 </ci> </bvar> <apply> <times/> <ci> species_v_14 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_20" metaid="metaid_0000017" name="function_4_Transition camR_ca3_BCD to camT_ca3_BCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_15 </ci> </bvar> <apply> <times/> <ci> species_v_15 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cB </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_8" metaid="metaid_0000018" name="function_4_Transition camR_ca2_BC to camT_ca2_BC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_9 </ci> </bvar> <apply> <times/> <ci> species_v_9 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cB </ci> <ci> cC </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_9" metaid="metaid_0000019" name="function_4_Transition camR_ca2_BD to camT_ca2_BD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_10 </ci> </bvar> <apply> <times/> <ci> species_v_10 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cB </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_10" metaid="metaid_0000020" name="function_4_Transition camR_ca2_CD to camT_ca2_CD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_11 </ci> </bvar> <apply> <times/> <ci> species_v_11 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_11" metaid="metaid_0000021" name="function_4_Transition camT_ca2_AB to camR_ca2_AB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> species_v_22 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_22 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_12" metaid="metaid_0000022" name="function_4_Transition camT_ca2_AC to camR_ca2_AC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> species_v_23 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_23 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cC </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_21" metaid="metaid_0000023" name="function_4_Transition camT_ca3_ABC to camR_ca3_ABC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> species_v_28 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_28 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cC </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_22" metaid="metaid_0000024" name="function_4_Transition camT_ca3_ABD to camR_ca3_ABD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> species_v_29 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_29 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_23" metaid="metaid_0000025" name="function_4_Transition camT_ca3_ACD to camR_ca3_ACD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> species_v_30 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_30 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_24" metaid="metaid_0000026" name="function_4_Transition camT_ca3_BCD to camR_ca3_BCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> species_v_31 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_31 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cB </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_25" metaid="metaid_0000027" name="function_4_Transition camR_ca4_ABCD to camT_ca4_ABCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> kRT </ci> </bvar> <bvar> <ci> species_v_16 </ci> </bvar> <apply> <times/> <ci> species_v_16 </ci> <ci> kRT </ci> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> <functionDefinition id="function_26" metaid="metaid_0000028" name="function_4_Transition camT_ca4_ABCD to camR_ca4_ABCD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <lambda> <bvar> <ci> kTR </ci> </bvar> <bvar> <ci> cA </ci> </bvar> <bvar> <ci> cB </ci> </bvar> <bvar> <ci> cC </ci> </bvar> <bvar> <ci> cD </ci> </bvar> <bvar> <ci> species_v_32 </ci> </bvar> <apply> <divide/> <apply> <times/> <ci> species_v_32 </ci> <ci> kTR </ci> </apply> <apply> <power/> <apply> <times/> <ci> cA </ci> <ci> cB </ci> <ci> cC </ci> <ci> cD </ci> </apply> <apply> <divide/> <cn> 1 </cn> <cn> 2 </cn> </apply> </apply> </apply> </lambda> </math> </functionDefinition> </listOfFunctionDefinitions> <listOfCompartments> <compartment id="Spine" metaid="metaid_0000090" name="Spine" size="1e-15"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000090"> <bqbiol:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0043197"/> </rdf:Bag> </bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </compartment> </listOfCompartments> <listOfSpecies> <species compartment="Spine" id="camR" initialConcentration="9.7e-12" metaid="metaid_0000091" name="camR"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000091"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:isVersionOf> <bqbiol:isHomologTo> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:uniprot:P62158"/> </rdf:Bag> </bqbiol:isHomologTo> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="ca" initialConcentration="1e-05" metaid="metaid_0000092" name="ca"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000092"> <bqbiol:is> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00076"/> </rdf:Bag> </bqbiol:is> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="camR_ca1_A" initialConcentration="0" metaid="metaid_0000093" name="camR_ca1_A"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000093"> <bqbiol:hasPart> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:hasPart> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="camR_ca1_B" initialConcentration="0" metaid="metaid_0000094" name="camR_ca1_B"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000094"> <bqbiol:hasPart> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/> <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/> </rdf:Bag> </bqbiol:hasPart> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="camR_ca1_C" initialConcentration="0" metaid="metaid_0000095" name="camR_ca1_C"/> <species compartment="Spine" id="camR_ca1_D" initialConcentration="0" metaid="metaid_0000096" name="camR_ca1_D"/> <species compartment="Spine" id="camR_ca2_AB" initialConcentration="0" metaid="metaid_0000097" name="camR_ca2_AB"/> <species compartment="Spine" id="camR_ca2_AC" initialConcentration="0" metaid="metaid_0000098" name="camR_ca2_AC"/> <species compartment="Spine" id="camR_ca2_AD" initialConcentration="0" metaid="metaid_0000099" name="camR_ca2_AD"/> <species compartment="Spine" id="camR_ca2_BC" initialConcentration="0" metaid="metaid_0000100" name="camR_ca2_BC"/> <species compartment="Spine" id="camR_ca2_BD" initialConcentration="0" metaid="metaid_0000101" name="camR_ca2_BD"/> <species compartment="Spine" id="camR_ca2_CD" initialConcentration="0" metaid="metaid_0000102" name="camR_ca2_CD"/> <species compartment="Spine" id="camR_ca3_ABC" initialConcentration="0" metaid="metaid_0000103" name="camR_ca3_ABC"/> <species compartment="Spine" id="camR_ca3_ABD" initialConcentration="0" metaid="metaid_0000104" name="camR_ca3_ABD"/> <species compartment="Spine" id="camR_ca3_ACD" initialConcentration="0" metaid="metaid_0000105" name="camR_ca3_ACD"/> <species compartment="Spine" id="camR_ca3_BCD" initialConcentration="0" metaid="metaid_0000106" name="camR_ca3_BCD"/> <species compartment="Spine" id="camR_ca4_ABCD" initialConcentration="0" metaid="metaid_0000107" name="camR_ca4_ABCD"/> <species compartment="Spine" id="camT" initialConcentration="2e-07" metaid="metaid_0000108" name="camT"/> <species compartment="Spine" id="camT_ca1_A" initialConcentration="0" metaid="metaid_0000109" name="camT_ca1_A"/> <species compartment="Spine" id="camT_ca1_B" initialConcentration="0" metaid="metaid_0000110" name="camT_ca1_B"/> <species compartment="Spine" id="camT_ca1_C" initialConcentration="0" metaid="metaid_0000111" name="camT_ca1_C"/> <species compartment="Spine" id="camT_ca1_D" initialConcentration="0" metaid="metaid_0000112" name="camT_ca1_D"/> <species compartment="Spine" id="camT_ca2_AB" initialConcentration="0" metaid="metaid_0000113" name="camT_ca2_AB"/> <species compartment="Spine" id="camT_ca2_AC" initialConcentration="0" metaid="metaid_0000114" name="camT_ca2_AC"/> <species compartment="Spine" id="camT_ca2_AD" initialConcentration="0" metaid="metaid_0000115" name="camT_ca2_AD"/> <species compartment="Spine" id="camT_ca2_BC" initialConcentration="0" metaid="metaid_0000116" name="camT_ca2_BC"/> <species compartment="Spine" id="camT_ca2_BD" initialConcentration="0" metaid="metaid_0000117" name="camT_ca2_BD"/> <species compartment="Spine" id="camT_ca2_CD" initialConcentration="0" metaid="metaid_0000118" name="camT_ca2_CD"/> <species compartment="Spine" id="camT_ca3_ABC" initialConcentration="0" metaid="metaid_0000119" name="camT_ca3_ABC"/> <species compartment="Spine" id="camT_ca3_ABD" initialConcentration="0" metaid="metaid_0000120" name="camT_ca3_ABD"/> <species compartment="Spine" id="camT_ca3_ACD" initialConcentration="0" metaid="metaid_0000121" name="camT_ca3_ACD"/> <species compartment="Spine" id="camT_ca3_BCD" initialConcentration="0" metaid="metaid_0000122" name="camT_ca3_BCD"/> <species compartment="Spine" id="camT_ca4_ABCD" initialConcentration="0" metaid="metaid_0000123" name="camT_ca4_ABCD"/> <species compartment="Spine" id="CaMKII" initialConcentration="7e-05" metaid="metaid_0000124" name="CaMKII"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000124"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:interpro:IPR015742"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="camR_CaMKII" initialConcentration="0" metaid="metaid_0000125" name="camR_CaMKII"/> <species compartment="Spine" id="camR_ca1_A_CaMKII" initialConcentration="0" metaid="metaid_0000126" name="camR_ca1_A_CaMKII"/> <species compartment="Spine" id="camR_ca1_B_CaMKII" initialConcentration="0" metaid="metaid_0000127" name="camR_ca1_B_CaMKII"/> <species compartment="Spine" id="camR_ca1_C_CaMKII" initialConcentration="0" metaid="metaid_0000128" name="camR_ca1_C_CaMKII"/> <species compartment="Spine" id="camR_ca1_D_CaMKII" initialConcentration="0" metaid="metaid_0000129" name="camR_ca1_D_CaMKII"/> <species compartment="Spine" id="camR_ca2_AB_CaMKII" initialConcentration="0" metaid="metaid_0000130" name="camR_ca2_AB_CaMKII"/> <species compartment="Spine" id="camR_ca2_AC_CaMKII" initialConcentration="0" metaid="metaid_0000131" name="camR_ca2_AC_CaMKII"/> <species compartment="Spine" id="camR_ca2_AD_CaMKII" initialConcentration="0" metaid="metaid_0000132" name="camR_ca2_AD_CaMKII"/> <species compartment="Spine" id="camR_ca2_BC_CaMKII" initialConcentration="0" metaid="metaid_0000133" name="camR_ca2_BC_CaMKII"/> <species compartment="Spine" id="camR_ca2_BD_CaMKII" initialConcentration="0" metaid="metaid_0000134" name="camR_ca2_BD_CaMKII"/> <species compartment="Spine" id="camR_ca2_CD_CaMKII" initialConcentration="0" metaid="metaid_0000135" name="camR_ca2_CD_CaMKII"/> <species compartment="Spine" id="camR_ca3_ABC_CaMKII" initialConcentration="0" metaid="metaid_0000136" name="camR_ca3_ABC_CaMKII"/> <species compartment="Spine" id="camR_ca3_ABD_CaMKII" initialConcentration="0" metaid="metaid_0000137" name="camR_ca3_ABD_CaMKII"/> <species compartment="Spine" id="camR_ca3_ACD_CaMKII" initialConcentration="0" metaid="metaid_0000138" name="camR_ca3_ACD_CaMKII"/> <species compartment="Spine" id="camR_ca3_BCD_CaMKII" initialConcentration="0" metaid="metaid_0000139" name="camR_ca3_BCD_CaMKII"/> <species compartment="Spine" id="camR_ca4_ABCD_CaMKII" initialConcentration="0" metaid="metaid_0000140" name="camR_ca4_ABCD_CaMKII"/> <species compartment="Spine" id="PP2B" initialConcentration="1.6e-06" metaid="metaid_0000141" name="PP2B"> <annotation> <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"> <rdf:Description rdf:about="#metaid_0000141"> <bqbiol:isVersionOf> <rdf:Bag> <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005955"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> </species> <species compartment="Spine" id="camR_PP2B" initialConcentration="0" metaid="metaid_0000142" name="camR_PP2B"/> <species compartment="Spine" id="camR_ca1_A_PP2B" initialConcentration="0" metaid="metaid_0000143" name="camR_ca1_A_PP2B"/> <species compartment="Spine" id="camR_ca1_B_PP2B" initialConcentration="0" metaid="metaid_0000144" name="camR_ca1_B_PP2B"/> <species compartment="Spine" id="camR_ca1_C_PP2B" initialConcentration="0" metaid="metaid_0000145" name="camR_ca1_C_PP2B"/> <species compartment="Spine" id="camR_ca1_D_PP2B" initialConcentration="0" metaid="metaid_0000146" name="camR_ca1_D_PP2B"/> <species compartment="Spine" id="camR_ca2_AB_PP2B" initialConcentration="0" metaid="metaid_0000147" name="camR_ca2_AB_PP2B"/> <species compartment="Spine" id="camR_ca2_AC_PP2B" initialConcentration="0" metaid="metaid_0000148" name="camR_ca2_AC_PP2B"/> <species compartment="Spine" id="camR_ca2_AD_PP2B" initialConcentration="0" metaid="metaid_0000149" name="camR_ca2_AD_PP2B"/> <species compartment="Spine" id="camR_ca2_BC_PP2B" initialConcentration="0" metaid="metaid_0000150" name="camR_ca2_BC_PP2B"/> <species compartment="Spine" id="camR_ca2_BD_PP2B" initialConcentration="0" metaid="metaid_0000151" name="camR_ca2_BD_PP2B"/> <species compartment="Spine" id="camR_ca2_CD_PP2B" initialConcentration="0" metaid="metaid_0000152" name="camR_ca2_CD_PP2B"/> <species compartment="Spine" id="camR_ca3_ABC_PP2B" initialConcentration="0" metaid="metaid_0000153" name="camR_ca3_ABC_PP2B"/> <species compartment="Spine" id="camR_ca3_ABD_PP2B" initialConcentration="0" metaid="metaid_0000154" name="camR_ca3_ABD_PP2B"/> <species compartment="Spine" id="camR_ca3_ACD_PP2B" initialConcentration="0" metaid="metaid_0000155" name="camR_ca3_ACD_PP2B"/> <species compartment="Spine" id="camR_ca3_BCD_PP2B" initialConcentration="0" metaid="metaid_0000156" name="camR_ca3_BCD_PP2B"/> <species compartment="Spine" id="camR_ca4_ABCD_PP2B" initialConcentration="0" metaid="metaid_0000157" name="camR_ca4_ABCD_PP2B"/> </listOfSpecies> <listOfParameters> <parameter id="kon" metaid="metaid_0000029" name="kon" value="1000000"/> <parameter constant="false" id="koffRA" metaid="metaid_0000030" name="koffRA" value="8.32"/> <parameter constant="false" id="koffRB" metaid="metaid_0000031" name="koffRB" value="0.0166"/> <parameter constant="false" id="koffRC" metaid="metaid_0000032" name="koffRC" value="17.4"/> <parameter constant="false" id="koffRD" metaid="metaid_0000033" name="koffRD" value="0.0145"/> <parameter constant="false" id="koffTA" metaid="metaid_0000034" name="koffTA" value="2101.0101010101"/> <parameter constant="false" id="koffTB" metaid="metaid_0000035" name="koffTB" value="4.19191919191919"/> <parameter constant="false" id="koffTC" metaid="metaid_0000036" name="koffTC" value="4393.93939393939"/> <parameter constant="false" id="koffTD" metaid="metaid_0000037" name="koffTD" value="3.66161616161616"/> <parameter id="kRT" metaid="metaid_0000038" name="kRT" value="1000000"/> <parameter constant="false" id="kTR" metaid="metaid_0000039" name="kTR" value="48.3792936623125"/> <parameter id="cA" metaid="metaid_0000040" name="cA" value="0.00396"/> <parameter id="cB" metaid="metaid_0000041" name="cB" value="0.00396"/> <parameter id="cC" metaid="metaid_0000042" name="cC" value="0.00396"/> <parameter id="cD" metaid="metaid_0000043" name="cD" value="0.00396"/> <parameter id="konCaMKII" metaid="metaid_0000044" name="konCaMKII" value="3200000"/> <parameter id="koffCaMKII" metaid="metaid_0000045" name="koffCaMKII" value="0.343"/> <parameter id="konPP2B" metaid="metaid_0000046" name="konPP2B" value="46000000"/> <parameter id="koffPP2B" metaid="metaid_0000047" name="koffPP2B" value="0.4"/> <parameter constant="false" id="free_camR_ca3_total" metaid="metaid_0000048" name="free_camR_ca3_total" value="0"/> <parameter constant="false" id="free_camT_ca3_total" metaid="metaid_0000049" name="free_camT_ca3_total" value="0"/> <parameter constant="false" id="free_cam_ca3_total" metaid="metaid_0000050" name="free_cam_ca3_total" value="0"/> <parameter constant="false" id="cam_ca4_total" metaid="metaid_0000051" name="cam_ca4_total" value="0"/> <parameter constant="false" id="CaMKII_camR_ca1" metaid="metaid_0000052" name="CaMKII_camR_ca1" value="0"/> <parameter constant="false" id="CaMKII_camR_ca2" metaid="metaid_0000053" name="CaMKII_camR_ca2" value="0"/> <parameter constant="false" id="CaMKII_camR_ca3" metaid="metaid_0000054" name="CaMKII_camR_ca3" value="0"/> <parameter constant="false" id="total_CaMKII_bound" metaid="metaid_0000055" name="total_CaMKII_bound" value="0"/> <parameter constant="false" id="total_CaMKII" metaid="metaid_0000056" name="total CaMKII" value="7e-05"/> <parameter constant="false" id="CaMKIIbar" metaid="metaid_0000057" name="CaMKIIbar" value="0"/> <parameter constant="false" id="PP2B_camR_ca1" metaid="metaid_0000058" name="PP2B_camR_ca1" value="0"/> <parameter constant="false" id="PP2B_camR_ca2" metaid="metaid_0000059" name="PP2B_camR_ca2" value="0"/> <parameter constant="false" id="PP2B_camR_ca3" metaid="metaid_0000060" name="PP2B_camR_ca3" value="0"/> <parameter constant="false" id="total_PP2B_bound" metaid="metaid_0000061" name="total_PP2B_bound" value="0"/> <parameter constant="false" id="total_PP2B" metaid="metaid_0000062" name="total PP2B" value="1.6e-06"/> <parameter constant="false" id="PP2Bbar" metaid="metaid_0000063" name="PP2Bbar" value="0"/> <parameter constant="false" id="camR_unbound" metaid="metaid_0000064" name="camR_unbound" value="9.7e-12"/> <parameter constant="false" id="total_camR" metaid="metaid_0000065" name="total camR" value="9.7e-12"/> <parameter constant="false" id="total_camT" metaid="metaid_0000066" name="total camT" value="2e-07"/> <parameter constant="false" id="Rbar" metaid="metaid_0000067" name="Rbar" value="4.84976478640786e-05"/> <parameter constant="false" id="cam_ca3_total" metaid="metaid_0000068" name="cam_ca3_total" value="0"/> <parameter constant="false" id="free_camR_ca2_total" metaid="metaid_0000069" name="free_camR_ca2_total" value="0"/> <parameter constant="false" id="free_camT_ca2_total" metaid="metaid_0000070" name="free_camT_ca2_total" value="0"/> <parameter constant="false" id="free_cam_ca2_total" metaid="metaid_0000071" name="free_cam_ca2_total" value="0"/> <parameter constant="false" id="cam_ca2_total" metaid="metaid_0000072" name="cam_ca2_total" value="0"/> <parameter constant="false" id="free_cam_ca1_total" metaid="metaid_0000073" name="free_cam_ca1_total" value="0"/> <parameter constant="false" id="cam_ca1_total" metaid="metaid_0000074" name="cam_ca1_total" value="0"/> <parameter constant="false" id="cam_ca0_total" metaid="metaid_0000075" name="cam_ca0_total" value="2.000097e-07"/> <parameter constant="false" id="cam_total" metaid="metaid_0000076" name="cam_total" value="2.000097e-07"/> <parameter constant="false" id="moles_bound_ca_per_moles_cam" metaid="metaid_0000077" name="moles_bound_ca_per_moles_cam" value="0"/> <parameter id="L" metaid="metaid_0000078" name="L" value="20670"/> <parameter id="KRA" metaid="metaid_0000079" name="KRA" value="8.32e-06"/> <parameter id="KRB" metaid="metaid_0000080" name="KRB" value="1.66e-08"/> <parameter id="KRC" metaid="metaid_0000081" name="KRC" value="1.74e-05"/> <parameter id="KRD" metaid="metaid_0000082" name="KRD" value="1.45e-08"/> <parameter constant="false" id="epsilon" metaid="metaid_0000087" name="epsilon" value="4.84976478640786e-05"/> <parameter constant="false" id="ybar" metaid="metaid_0000088" name="ybar" value="0"/> <parameter constant="false" id="ybar1ybar" metaid="metaid_0000089" name="ybar/(1-ybar)" value="0"/> </listOfParameters> <listOfRules> <assignmentRule metaid="metaid_0000158" variable="koffRA"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> KRA </ci> <ci> kon </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000159" variable="free_camT_ca3_total"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <plus/> <ci> camT_ca3_ABC </ci> <ci> camT_ca3_ABD </ci> <ci> camT_ca3_ACD </ci> <ci> camT_ca3_BCD </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000160" variable="koffRB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> KRB </ci> <ci> kon </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000161" variable="koffRC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> KRC </ci> <ci> kon </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000162" variable="koffRD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> KRD </ci> <ci> kon </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000163" variable="koffTA"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> koffRA </ci> <ci> cA </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000164" variable="koffTB"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> koffRB </ci> <ci> cB </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000165" variable="koffTC"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> koffRC </ci> <ci> cC </ci> </apply> </math> </assignmentRule> <assignmentRule metaid="metaid_0000166" variable="koffTD"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <divide/> <ci> koffRD </ci> <ci> cD </ci> </apply> </math> </assignmentRule> <assignmentRule 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metaid="metaid_0000372" name="CaMKII binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_BD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_BD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca2_BD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_169" metaid="metaid_0000373" name="CaMKII binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_CD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_CD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca2_CD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_170" metaid="metaid_0000374" name="CaMKII binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ABC"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABC_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca3_ABC </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_171" metaid="metaid_0000375" name="CaMKII binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ABD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca3_ABD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_172" metaid="metaid_0000376" name="CaMKII binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ACD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ACD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca3_ACD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_173" metaid="metaid_0000377" name="CaMKII binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_BCD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_BCD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca3_BCD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_174" metaid="metaid_0000378" name="CaMKII binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca4_ABCD"/> <speciesReference species="CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca4_ABCD_CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konCaMKII </ci> <ci> camR_ca4_ABCD </ci> <ci> CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_175" metaid="metaid_0000379" name="CaMKII dissociation from camR" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_176" metaid="metaid_0000380" name="CaMKII dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca1_A_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_A"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca1_A_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_177" metaid="metaid_0000381" name="CaMKII dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca1_B_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_B"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca1_B_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_178" metaid="metaid_0000382" name="CaMKII dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca1_C_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_C"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca1_C_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_179" metaid="metaid_0000383" name="CaMKII dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca1_D_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_D"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca1_D_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_180" metaid="metaid_0000384" name="CaMKII dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_AB_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AB"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_AB_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_181" metaid="metaid_0000385" name="CaMKII dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_AC_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AC"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_AC_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_182" metaid="metaid_0000386" name="CaMKII dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_AD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_AD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_183" metaid="metaid_0000387" name="CaMKII dissociation from camR_ca2_BC" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_BC_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_BC"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_BC_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_184" metaid="metaid_0000388" name="CaMKII dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_BD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_BD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_BD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_185" metaid="metaid_0000389" name="CaMKII dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca2_CD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_CD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca2_CD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_186" metaid="metaid_0000390" name="CaMKII dissociation from camR_ca3_ABC" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_ABC_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABC"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca3_ABC_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_187" metaid="metaid_0000391" name="CaMKII dissociation from camR_ca3_ABD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_ABD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca3_ABD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_188" metaid="metaid_0000392" name="CaMKII dissociation from camR_ca3_ACD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_ACD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ACD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca3_ACD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_189" metaid="metaid_0000393" name="CaMKII dissociation from camR_ca3_BCD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_BCD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_BCD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca3_BCD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_190" metaid="metaid_0000394" name="CaMKII dissociation from camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca4_ABCD_CaMKII"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca4_ABCD"/> <speciesReference species="CaMKII"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffCaMKII </ci> <ci> camR_ca4_ABCD_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_191" metaid="metaid_0000395" name="PP2B binding to camR" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_192" metaid="metaid_0000396" name="PP2B binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca1_A"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_A_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca1_A </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_193" metaid="metaid_0000397" name="PP2B binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca1_B"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_B_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca1_B </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_194" metaid="metaid_0000398" name="PP2B binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca1_C"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_C_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca1_C </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_195" metaid="metaid_0000399" name="PP2B binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca1_D"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca1_D_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca1_D </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_196" metaid="metaid_0000400" name="PP2B binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_AB"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AB_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_AB </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_197" metaid="metaid_0000401" name="PP2B binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_AC"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AC_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_AC </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_198" metaid="metaid_0000402" name="PP2B binding to camR_ca2_AD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_AD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_AD </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_199" metaid="metaid_0000403" name="PP2B binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_BC"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_BC_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_BC </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_200" metaid="metaid_0000404" name="PP2B binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_BD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_BD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_BD </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_201" metaid="metaid_0000405" name="PP2B binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_CD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_CD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca2_CD </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_202" metaid="metaid_0000406" name="PP2B binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ABC"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABC_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca3_ABC </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_203" metaid="metaid_0000407" name="PP2B binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ABD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ABD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca3_ABD </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_204" metaid="metaid_0000408" name="PP2B binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ACD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_ACD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> konPP2B </ci> <ci> camR_ca3_ACD </ci> <ci> PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_205" metaid="metaid_0000409" name="PP2B binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_BCD"/> <speciesReference species="PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_BCD_PP2B"/> </listOfProducts> <kineticLaw> <math 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<listOfProducts> <speciesReference species="camR_ca3_ABD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> kon </ci> <ci> camR_ca2_BD_PP2B </ci> <ci> ca </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_327" metaid="metaid_0000531" name="Ca binding to camR_ca2_BD_PP2B site C" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca2_BD_PP2B"/> <speciesReference species="ca"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca3_BCD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> kon </ci> <ci> camR_ca2_BD_PP2B </ci> <ci> ca </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_328" metaid="metaid_0000532" name="Ca binding to camR_ca2_CD_PP2B site A" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference 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</apply> </math> </kineticLaw> </reaction> <reaction id="reaction_334" metaid="metaid_0000538" name="Ca dissociation from camR_ca3_ABD_PP2B site B" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_ABD_PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AD_PP2B"/> <speciesReference species="ca"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffRB </ci> <ci> camR_ca3_ABD_PP2B </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_335" metaid="metaid_0000539" name="Ca dissociation from camR_ca3_ABD_PP2B site D" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camR_ca3_ABD_PP2B"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca2_AB_PP2B"/> <speciesReference species="ca"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> 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reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ABD_PP2B"/> <speciesReference species="ca"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca4_ABCD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> kon </ci> <ci> camR_ca3_ABD_PP2B </ci> <ci> ca </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_344" metaid="metaid_0000548" name="Ca binding to camR_ca3_ACD_PP2B site B" reversible="false" sboTerm="SBO:0000177"> <listOfReactants> <speciesReference species="camR_ca3_ACD_PP2B"/> <speciesReference species="ca"/> </listOfReactants> <listOfProducts> <speciesReference species="camR_ca4_ABCD_PP2B"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> kon </ci> <ci> camR_ca3_ACD_PP2B </ci> <ci> ca </ci> </apply> </math> </kineticLaw> </reaction> <reaction 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<speciesReference species="ca"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffRB </ci> <ci> camR_ca1_B_CaMKII </ci> </apply> </math> </kineticLaw> </reaction> <reaction id="reaction_351" metaid="metaid_0000555" name="Ca dissociating from camT_ca3_ABC site C" reversible="false" sboTerm="SBO:0000180"> <listOfReactants> <speciesReference species="camT_ca3_ABC"/> </listOfReactants> <listOfProducts> <speciesReference species="camT_ca2_AB"/> <speciesReference species="ca"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> Spine </ci> <ci> koffTC </ci> <ci> camT_ca3_ABC </ci> </apply> </math> </kineticLaw> </reaction> </listOfReactions> </model> </sbml>