# Just for a test-run # Should be used with spineIntegration.py { # desired biochemical file "biochemical_filename" : "biochemical_circuits/biomd183_loop.eml", "dtNeuron" : 0.025, # integration dt [ms] "delta_calcium_sampling" : 1, # In millisecond [ms]. # How often the calcium hasto be synchronized within ecell and Neuron . "t_equilibrium_neuron" : 100, # in milliseconds "t_equilibrium_ecell" : 300, # in seconds "tStop" : 1000, # [ms] Time to stop (NEURON time is the reference) the simulation "t_buffer" : 10, # [ms] For how long the syncronization should be carried "neuron_time_recording_interval" : 0.1, # Recording at every [ms] "weight_sampling" : 50, # Total ms when the weight of the synapses will be updated "big_spine" : True, "bio_on" : True, "spines_dist" : "two", # number of spines #spines_dist = 'all' or spines_dist=zero "stimulated_spines" : ['spine1'], "spine1" : ['ampa_s1', 'nmda_s1'], # Stimulus 1 "ampa_s1" : {"t_stim" : 0.1, # t_stim [s] "numbers" : 5, # number "delay" : 0.15, # delay [s] "type" : "ampa" # type }, "nmda_s1" : {"t_stim" : 0.1, # t_stim [s] "numbers" : 5, # number "delay" : 0.15, # delay [s] "type" : "nmda" # type }, "stimulated_sec_GABA" : [], "dend1" : ['gaba_s1'], # Stimulus GABA "gaba_s1" : {"t_stim" : 0.1, # t_stim [s] "numbers" : 1, # number "delay" : 0.25, # delay [s] "type" : "gaba" # type }, "kir_gkbar" : 0.00016, # S/cm2 "ca_leak_vmax" : 4e-3, "ca_pump_vmax" : 4e-3, 'nthreads' : 2, 'sec_to_rec' : ['all'], "var_to_plot" : ['v','cai','cali','ica', 'ical'] }