// Background synaptic activity in FS basket cells 2018 around 30 Hz to simulate the presynpatic cell firing in Gap junctions experiment. according to Tamas Somogyi 2000
//Alexandra Tzilivaki.
inhibitory_synapses=8
excitatory_synapses=20//32
ampaweightin=7.5e-4//*0.9
nmdaweightin=3.2e-4*5//*0.9
gabaaweightin=5.1e-4*14*0
//number_dendszero=$1
objref pevstiminh[excitatory_synapses], devstiminh[excitatory_synapses] ,pivstiminh[inhibitory_synapses], divstiminh[inhibitory_synapses]
objref ran
objref pampain_back[excitatory_synapses], pnmdain_back[excitatory_synapses], pgabaain_back[inhibitory_synapses]
objref pncampainback[excitatory_synapses], pncnmdainback[excitatory_synapses], pngabaaainback[inhibitory_synapses]
mean=0.02
objref dpool, rdend
dpool= new Vector(number_dendszero) // !!
j=0
for i= 0, number_dendszero-1{
dpool.x[j]=i
j=j+1
}
rdend=new Random(number_dendszero)
rdend.uniform(0,number_dendszero-1)
objref eDendperSyn, iDendperSyn
eDendperSyn= new Vector(excitatory_synapses,0)
iDendperSyn = new Vector(inhibitory_synapses,0)
for g=0,eDendperSyn.size()-1 {
eDendperSyn.x[g]=dpool.x[(rdend.uniform(0,dpool.size()-1))]
}
for f=0,iDendperSyn.size()-1 {
iDendperSyn.x[f]=dpool.x[(rdend.uniform(0,dpool.size()-1))]
}
objref rp
rp = new Random()
rp.poisson(mean)
print"123"
objref stimvectorE[excitatory_synapses]
objref stimvectorI[inhibitory_synapses]
for t=0,excitatory_synapses-1{
stimvectorE[t]= new Vector()
for k=0,int(tstop)-1{ // $1 the tstop
if(rp.repick()){
stimvectorE[t].append(k)
}
}
}
for j=0,inhibitory_synapses-1{
stimvectorI[j]= new Vector()
for l=0,int(tstop)-1{ // $1 the tstop
if(rp.repick()){
stimvectorI[j].append(l)
}
}
}
proc call_vecstim() {
ran = new Random(5)
PIDb = ran.uniform(0, 1)
// excitatory synapses in dendrites
for syn=0,excitatory_synapses-1 {
edendritis=eDendperSyn.x[syn]
pevstiminh[syn] = new VecStim(0.5)
pevstiminh[syn].delay = 0
pevstiminh[syn].play(stimvectorE[syn])
PIDb=ran.repick()
FSdetailedtemplate[$1].dend[edendritis] pampain_back[syn]=new CPGLUIN(PIDb)
FSdetailedtemplate[$1].dend[edendritis] pnmdain_back[syn]=new NMDAIN(PIDb)
pncampainback[syn] = new NetCon(pevstiminh[syn], pampain_back[syn], -20, 0, ampaweightin)
pncnmdainback[syn] = new NetCon(pevstiminh[syn], pnmdain_back[syn], -20, 0, nmdaweightin)
}
// inhibitory synapses in dendrites
for syn=0,inhibitory_synapses-1 {
idendritis=iDendperSyn.x[syn]
pivstiminh[syn] = new VecStim(0.5)
pivstiminh[syn].delay = 0
pivstiminh[syn].play(stimvectorI[syn])
PIDb=ran.repick()
FSdetailedtemplate[$1].dend[idendritis] pgabaain_back[syn]=new GABAain(PIDb)
pngabaaainback[syn] = new NetCon(pivstiminh[syn], pgabaain_back[syn], -30, 0, gabaaweightin)
}
} // procedure