TITLE H-current that uses Na ions
: Updated to use Cvode by Yiota Poirazi 12/1/2005
NEURON {
SUFFIX hcb
RANGE gbar,vhalf, K, taun, ninf, g, ihi
USEION hi READ ehi WRITE ihi VALENCE 1
}
UNITS {
(um) = (micrometer)
(mA) = (milliamp)
(uA) = (microamp)
(mV) = (millivolt)
(pmho) = (picomho)
(mmho) = (millimho)
}
:INDEPENDENT {t FROM 0 TO 1 WITH 100 (ms)}
PARAMETER { : parameters that can be entered when function is called in cell-setup
ena = 55 (mV)
ehi = -10 (mV)
K = 10.0 (mV)
gbar = 0 (mho/cm2) : initialize conductance to zero
vhalf = -90 (mV) : half potential
}
STATE { : the unknown parameters to be solved in the DEs
n
}
ASSIGNED {
v
ihi (mA/cm2)
ninf
taun (ms)
g
}
INITIAL {
rates()
n = ninf
g = gbar*n
ihi = g*(v-ehi)
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gbar*n
ihi = g*(v-ehi)
}
DERIVATIVE states {
rates()
n' = (ninf - n)/taun
}
PROCEDURE rates() {
if (v > -10) {
taun = 1
} else {
taun = 2*(1/(exp((v+145)/-17.5)+exp((v+16.8)/16.5)) + 10)
}
ninf = 1 - (1 / (1 + exp((vhalf - v)/K)))
}