This is a model of a midbrain dopamine neuron presented in the paper Tarfa RA, Evans RC, Khaliq ZM (2017) Enhanced sensitivity to hyperpolarizing inhibition in mesoaccumbal relative to nigrostriatal dopamine neuron subpopulations. J Neurosci This model was contributed by Dr R Evans and requires the GENESIS simulator which is freely available from: http://genesis-sim.org/ To run simulations as seen in figure 11, run "RunCell.g" from the genesis simulation environment. Default settings are: An A-type potassium channel with a slow inactivation time constant (200ms), which can be changed in the file DACell/channels/Kaf.g The other default settings which are altered in the paper are the Ih gmax = 0.5 S/m^2 and the T-type Ca channel permeability = 1e-7 cm/s (both in globals.g). Together these default settings make a 'VTA-like' midbrain dopamine neuron. When changing inactivation time constant for current clamp simulations, the Gmax (in DAcell/globals.g) for the Kaf channel was adjusted to make the peak currents similar in a single compartment voltage clamp simulation. The tau and gmax correspondance is: tau=200ms, gmax= 24.5 S/m^s tau=150ms, gmax= 24.5 S/m^s tau=100ms, gmax= 25 S/m^s tau=50ms, gmax= 27.5 S/m^s tau=25ms, gmax= 32 S/m^s Again, the tau is changed in the channel file (Kaf.g) and the gmax is changed in the globals file (globals.g) GABA stimulation simulations can be run by un-commenting "include DAstims/GABAstim.g" in RunCell.g