TITLE Calcium high-threshold L type current for RD Traub, J Neurophysiol 89:909-921, 2003
COMMENT
Implemented by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu)
ENDCOMMENT
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
}
NEURON {
SUFFIX cal
USEION ca WRITE ica
RANGE gbar, ica
RANGE alpha, beta : added to write rates for comparison with F
}
PARAMETER {
gbar = 0.0 (mho/cm2)
v (mV)
}
ASSIGNED {
ica (mA/cm2)
alpha (/ms) beta (/ms)
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
ica = gbar * m * m * ( v - 125 )
}
INITIAL {
settables(v)
m = alpha / ( alpha + beta )
m = 0
}
DERIVATIVE states {
settables(v)
m' = alpha * ( 1 - m ) - beta * m
}
UNITSOFF
PROCEDURE settables(v (mV)) { LOCAL tmp
TABLE alpha, beta FROM -120 TO 40 WITH 641
alpha = 1.6 / ( 1 + exp( - 0.072 * ( v - 5 ) ) )
tmp = v + 8.9
if ( fabs( tmp ) < 1e-6 ) {
beta = 0.1 * exp( - tmp / 5 )
}else{
beta = 0.02 * tmp / ( exp( tmp / 5 ) - 1 )
}
}
UNITSON