TITLE Delayed rectifier K current, for axonal compartments
COMMENT
from Table 4 of "A branching dendritic model of a rodent CA3 pyramidal neurone." Traub RD et al. J Physiol. (1994)
implemented by Nikita Vladimirov <nikita.vladimirov@gmail.com>
ENDCOMMENT
NEURON {
SUFFIX Kdrax
USEION k READ ek WRITE ik
RANGE gbar, g, i
GLOBAL Vm
}
UNITS {
(S) = (siemens)
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
gbar = 0 (S/cm2)
Vm = -65 (mV) : resting potential
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
i (mA/cm2)
g (S/cm2)
ninf
ntau (ms)
}
STATE { n }
BREAKPOINT {
SOLVE states METHOD cnexp
g = gbar * n^4
i = g * (v - ek)
ik = i
}
INITIAL {
rates(v)
n = ninf
}
DERIVATIVE states {
rates(v)
n' = (ninf-n)/ntau
}
PROCEDURE rates(v(mV)) {
LOCAL alphan, betan, small
TABLE ninf, ntau FROM -100 TO 50 WITH 200
UNITSOFF
small = (17.2 - (v - Vm) )/5
if ( fabs(small) > 1e-6 ) {
alphan = 0.03 * ( 17.2 - (v - Vm) ) / ( exp( (17.2 - (v - Vm) )/5 ) - 1)
} else {
alphan = 0.03 * 5 / ( 1 + small/2 )
}
betan = 0.45 * exp( (12 - (v - Vm) ) / 40 )
ninf = alphan / (alphan + betan)
ntau = 1 / (alphan + betan)
UNITSON
}