: from lt. Warman 94, Halliwell, Adams 82
UNITS
{
(mA) = (milliamp)
(mV) = (millivolt)
(S) = (siemens)
}
NEURON {
SUFFIX KM
USEION k READ ek WRITE ik
RANGE gMbar, gM, timesTau, plusTau
GLOBAL uinf, utau
}
PARAMETER
{
gMbar = 0.00034 (S/cm2) <0,1e9>
eK = -95 (mV)
ek (mV)
timesTau=1
plusTau=0
}
STATE
{
u
}
ASSIGNED
{
v (mV)
celsius (degC)
gM (S/cm2)
ik (mA/cm2)
uinf
utau (ms)
}
LOCAL uexp
BREAKPOINT
{
SOLVE states METHOD cnexp
gM = gMbar*u*u
ik = gM*(v - eK)
}
INITIAL
{
rates(v)
u = uinf
}
DERIVATIVE states
{
rates(v)
u' = (uinf-u)/utau
}
LOCAL q10
PROCEDURE rates(v(mV)) :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
{
LOCAL alpha, beta, sum
UNITSOFF
: siehe Warman-Paper
TABLE uinf, utau FROM -150 TO 150 WITH 3000 : Mitti
q10 = 5^((celsius - 23)/10)
:"u" potassium activation system
alpha = 0.016 / exp((v+52.7)/-23)
beta = 0.016 / exp((v+52.7)/18.8)
sum = alpha + beta
uinf = alpha/sum
utau = timesTau/(sum*q10)+plusTau
}
UNITSON