## Set file for /Users/sam/Desktop/3p/3p.ode on Mon Apr 29 20:37:26 2019 10 Number of equations and auxiliaries 59 Number of parameters # Numerical stuff 1 nout 40 nullcline mesh 8 Qual RK 10000 total 0.1 DeltaT 0 T0 0 Transient 5000000000000 Bound 1e-12 DtMin 1 DtMax 0.001 Tolerance 0.001 Abs. Tolerance 0 Max Delay 100 Eigenvector iterates 0.001 Eigenvector tolerance 0.001 Newton tolerance 0 Poincare plane 1e-05 Boundary value tolerance 1e-05 Boundary value epsilon 20 Boundary value iterates 0 Poincare None 1 Poincare variable 1 Poincare sign 0 Stop on Section 0 Delay flag 10000 Current time 10000 Last Time 1 MyStart 1 INFLAG # Delays 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 # Bndry conds 0 0 0 0 0 0 0 0 0 0 # Old ICs -14.5 V1 0.195 H1 0.925925 S1 0.925925 S1_P -61.6 V2 0.199 H2 0 S2 -75 V3 0.195 H3 0 S3 # Ending ICs -61.81844870492593 V1 0.8778254324605055 H1 5.809196309517561e-05 S1 0.01220522237092084 S1_P -13.35987033378684 V2 0.0942519055201155 H2 0.9245187598221296 S2 -25.31672248169878 V3 0.1813226397238274 H3 0.6164985472286295 S3 # Parameters 21 c 10 gnap 2.8 gl 60 gsyni 10 gsyne 5 gnap_e 2 gl_e 50 Ena -65 El -80 Esyn 0 EsynE -85 Ek -37 thetam -6 sigmam 6 sigmah -40 thetah_p -50 thetah_i/e 1750 epsilon_p 400 epsilon_i 1000 epsilon_e -25 thetatau_e -35 thetatau_i -30 thetatau_p -25 thetasyn -3 sigmasyn -8 sigsyn_pe -10 thetsyn_pe 1 pdscale 1 rtndscale 0.55 pd_i 0.11 pd_e 0 pd_p 0.45 rtnd_i 0.09 rtnd_e 0 rtnd_p 1 vago 1 gks_i 0.3 gks_e 0.15 gks_p 10 thr 10 conc 0.35 kalth_i 1 kalth_e 0.5 kalth_p 1 ks 0.0417 b_ei 0.001 b_ep 0.0417 b_ie 0 b_ip 1 a_pe 0.11 a_ie 1.5 dscale 0.5 delta_i 1 delta_e 1 delta_p 1 delta_l 1 alpha 0.08 beta 0.005 beta_p # Graphics 0.7071097251469876 rm -0.4999999999826661 rm 0.4999958366025516 rm 0.7071038372138505 rm 0.5000041633974482 rm -0.4999999999826661 rm 0 rm 0.7071038372138505 rm 0.7071097251469876 rm 0 1 1 1 0 0 5 1 1 9 0 8 1 1 7 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 0 1 1 1 0 -1000 1000 0 0 3DFlag 1 Timeflag 0 Colorflag 0 Type 1 color scale 0 minscale 10000 xmax 0 xmin 20 ymax -80 ymin 12 zmax -12 zmin 5000 0.0002 -30 0.02 0 0.08333333333333333 45 Theta 45 Phi 0 xshft 0 yshft 0 zshft 0 xlo -80 ylo 0 -80 10000 xhi 20 yhi 10000 20 # Transpose variables etc V1 2 n columns 1 n rows 1 row skip 1 col skip 1 row 0 # Coupling stuff for H funs 0 0 0 0 0 0 0 0 0 0 # Array plot stuff 1 NCols 0 Row 1 50 NRows 8 RowSkip 0 Zmin 1 Zmax # Torus information 0 Torus flag 1=ON 6.283185307179586 Torus period # Range information c -1 eq-range stab col 0 shoot flag 1=on 10 eq-range steps 0 eq_range low 1 eq_range high V1 V1 20 Range steps 0 Cycle color 1=on 1 Reset data 1=on 1 Use old I.C.s 1=yes 0 Par1 low 0 Par2 low 1 Par1 high 1 Par2 high c 0 BVP side 0 color cycle flag 1=on 10 BVP range steps 0 BVP range low 1 BVP range high RHS etc ... dV1/dT=(-INAP(V1,H1,GNAP)-IL(V1,GL)-IAPP(V1,C_I)-ISYN(V1,S2,B_EI,KALTH_I)-IKS(V1,GKS_I)-W_I*DELTA_I*DSCALE)/C dH1/dT=(HINF(V1,THETAH_I/E)-H1)/TAUH(V1,EPSILON_I,THETATAU_I) dS1/dT=ALPHA*(1-S1)*SINF(V1,THETASYN,SIGMASYN)-BETA*S1 dS1_P/dT=ALPHA*(1-S1_P)*SINF(V1,THETASYN,SIGMASYN)-BETA_P*S1_P dV2/dT=(-INAP(V2,H2,GNAP_E)-IL(V2,GL_E)-IAPP(V2,C_E)-ISYN(V2,S1,B_IE,KALTH_E)-ISYNE(V2,S1,A_IE*VAGO)-ISYNE(V2,S3,A_PE)-IKS(V2,GKS_E)-W_E*DELTA_E*DSCALE)/C dH2/dT=(HINF(V2,THETAH_I/E)-H2)/TAUH(V2,EPSILON_E,THETATAU_E) dS2/dT=ALPHA*(1-S2)*SINF(V2,THETASYN,SIGMASYN)-BETA*S2 dV3/dT=(-INAP(V3,H3,GNAP)-IL(V3,GL)-IAPP(V3,C_P)-ISYN(V3,S2,B_EP,KALTH_P)-ISYN(V3,S1_P,B_IP*VAGO,KALTH_P)-IKS(V3,GKS_P)-W_P*DELTA_P*DSCALE)/C dH3/dT=(HINF(V3,THETAH_P)-H3)/TAUH(V3,EPSILON_P,THETATAU_P) dS3/dT=ALPHA*(1-S3)*SINF(V3,THETSYN_PE,SIGSYN_PE)-BETA*S3 where ... C_I = PDSCALE*PD_I+RTNDSCALE*RTND_I C_E = PDSCALE*PD_E+RTNDSCALE*RTND_E C_P = PDSCALE*PD_P+RTNDSCALE*RTND_P MKS = 1/(1+EXP(-(CONC-THR)/2)) User-defined functions: HINF(V,THETAH) = 1/(1+EXP((V-THETAH)/SIGMAH)) SINF(V,THETA,SIGMA) = 1/(1+EXP((V-THETA)/SIGMA)) TAUH(V,EP,THETA) = EP/(COSH((V-THETA)/SIGMAH/2)) MINF(V) = 1/(1+EXP((V-THETAM)/SIGMAM)) ISYN(V,S,B,KALTH) = GSYNI*B*S*(1+KS*KALTH)*(V-ESYN) ISYNE(V,S,A) = GSYNE*A*S*(V-ESYNE) INAP(V,H,G) = G*MINF(V)*H*(V-ENA) IL(V,G) = G*(V-EL) IAPP(V,C) = C*V IKS(V,G) = G*MKS*(V-EK)