//To simulate the huwentoxin effect, hw=0, bw=0.8, qa=6.4 and cana=0.2
//To simulate any other block, the corresponding conductance is 80% less
proc run_control() {
hw_na12 = 0.015
bw_na12 = 1
qa_na12 = 6.8
cana_na12 = 0.4
gca_soma = 0.0005
gca_ais1 = 0.0005
gca_ais2 = 3e-05
gca_ais3 = 0
git2_soma = 0.0003
git2_ais1 = 0.0001
git2_ais2 = 3e-05
git2_ais3 = 3e-06
gskca_soma = 0.02
gbkca_soma = 10
gskca_ais = 0.02
gbkca_ais = 1000
init_channels()
run()
}
proc run_na12() {
hw_na12 = 0.0
bw_na12 = 0.8
qa_na12 = 6.4
cana_na12 = 0.2
gca_soma = 0.0005
gca_ais1 = 0.0005
gca_ais2 = 3e-05
gca_ais3 = 0
git2_soma = 0.0003
git2_ais1 = 0.0001
git2_ais2 = 3e-05
git2_ais3 = 3e-06
gskca_soma = 0.02
gbkca_soma = 10
gskca_ais = 0.02
gbkca_ais = 1000
init_channels()
run()
}
proc run_sk() {
hw_na12 = 0.015
bw_na12 = 1
qa_na12 = 6.8
cana_na12 = 0.4
gca_soma = 0.0005
gca_ais1 = 0.0005
gca_ais2 = 3e-05
gca_ais3 = 0
git2_soma = 0.0003
git2_ais1 = 0.0001
git2_ais2 = 3e-05
git2_ais3 = 3e-06
gskca_soma = 0.02*0.2
gbkca_soma = 10
gskca_ais = 0.02*0.2
gbkca_ais = 1000
init_channels()
run()
}
proc run_bk() {
hw_na12 = 0.015
bw_na12 = 1
qa_na12 = 6.8
cana_na12 = 0.4
gca_soma = 0.0005
gca_ais1 = 0.0005
gca_ais2 = 3e-05
gca_ais3 = 0
git2_soma = 0.0003
git2_ais1 = 0.0001
git2_ais2 = 3e-05
git2_ais3 = 3e-06
gskca_soma = 0.02
gbkca_soma = 10*0.2
gskca_ais = 0.02
gbkca_ais = 1000*0.2
init_channels()
run()
}
proc run_vgcc() {
hw_na12 = 0.015
bw_na12 = 1
qa_na12 = 6.8
cana_na12 = 0.4
gca_soma = 0.0005*0.2
gca_ais1 = 0.0005*0.2
gca_ais2 = 3e-05*0.2
gca_ais3 = 0
git2_soma = 0.0003*0.2
git2_ais1 = 0.0001*0.2
git2_ais2 = 3e-05*0.2
git2_ais3 = 3e-06*0.2
gskca_soma = 0.02
gbkca_soma = 10
gskca_ais = 0.02
gbkca_ais = 1000
init_channels()
run()
}