// In use 10/10/2004 -- present
// Add striatal synapses, but normalize rate by compartment surface area.
/* The following params must be set prior to calling this file:
str striatumfname: file name of compartments to get striatal inputs
int num_striatum_compts: number of compartments to get striatal inputs
int num_striatum_per_comp: # striatal syns per selected compartment.
All are currently initialized and set in GP$1_defaults.g, but can be
overwritten as needed.
Modified 10/10/2004: made the rate of each compartment's striatal inputs
normalized by that compartment's surface area relative to the mean surface
area for all compartments receiving striatal input. So the total number of
events arriving at the "average" compartment =
{striatum_rate} * {num_striatum_per_comp}
This input rate can be translated to a constant, uniform input in units of
events / sec / micron2 by dividing {striatum_rate} * {num_striatum_per_comp}
by the total surface area of the dendritic compartments receiving input.
*/
randseed 78123456
int i
str striatumcompartment
//create input element tree outside of the cell path
if (!{exists /inputs})
create neutral /inputs
end
create neutral /inputs/striatum
//cycle through each selected compartment and add synapses
for (i = 1; i <= {num_striatum_compts}; i = i + 1)
striatumcompartment = "soma"
str GABAname = "GABA" @ {i}
copy /library/GABA {cellpath}/{striatumcompartment}/{GABAname}
addmsg {cellpath}/{striatumcompartment}/{GABAname} {cellpath}/{striatumcompartment} CHANNEL Gk Ek
addmsg {cellpath}/{striatumcompartment} {cellpath}/{striatumcompartment}/{GABAname} VOLTAGE Vm
setfield {cellpath}/{striatumcompartment}/{GABAname} gmax {G_GABA}
str timetableName = "timetable" @ {i}
str spikegenName = "spikegen" @ {i}
//set up timetables
create timetable /inputs/striatum/{timetableName}
if ({striatum_rate} > 0)
setfield /inputs/striatum/{timetableName} maxtime {rundur} act_val 1.0 method 1 meth_desc1 {1/{striatum_rate}}
call /inputs/striatum/{timetableName} TABFILL
end
//set up spikegen
create spikegen /inputs/striatum/{spikegenName}
setfield /inputs/striatum/{spikegenName} output_amp 1 thresh 0.5
//connect timetables to GABA synapses
if ({striatum_rate} > 0)
addmsg /inputs/striatum/{timetableName} /inputs/striatum/{spikegenName} INPUT activation
addmsg /inputs/striatum/{spikegenName} {cellpath}/{striatumcompartment}/{GABAname} SPIKE
end
end