// In use 10/10/2004 -- present // Add striatal synapses, but normalize rate by compartment surface area. /* The following params must be set prior to calling this file: str striatumfname: file name of compartments to get striatal inputs int num_striatum_compts: number of compartments to get striatal inputs int num_striatum_per_comp: # striatal syns per selected compartment. All are currently initialized and set in GP$1_defaults.g, but can be overwritten as needed. Modified 10/10/2004: made the rate of each compartment's striatal inputs normalized by that compartment's surface area relative to the mean surface area for all compartments receiving striatal input. So the total number of events arriving at the "average" compartment = {striatum_rate} * {num_striatum_per_comp} This input rate can be translated to a constant, uniform input in units of events / sec / micron2 by dividing {striatum_rate} * {num_striatum_per_comp} by the total surface area of the dendritic compartments receiving input. */ randseed 78123456 int i str striatumcompartment //create input element tree outside of the cell path if (!{exists /inputs}) create neutral /inputs end create neutral /inputs/striatum //cycle through each selected compartment and add synapses for (i = 1; i <= {num_striatum_compts}; i = i + 1) striatumcompartment = "soma" str GABAname = "GABA" @ {i} copy /library/GABA {cellpath}/{striatumcompartment}/{GABAname} addmsg {cellpath}/{striatumcompartment}/{GABAname} {cellpath}/{striatumcompartment} CHANNEL Gk Ek addmsg {cellpath}/{striatumcompartment} {cellpath}/{striatumcompartment}/{GABAname} VOLTAGE Vm setfield {cellpath}/{striatumcompartment}/{GABAname} gmax {G_GABA} str timetableName = "timetable" @ {i} str spikegenName = "spikegen" @ {i} //set up timetables create timetable /inputs/striatum/{timetableName} if ({striatum_rate} > 0) setfield /inputs/striatum/{timetableName} maxtime {rundur} act_val 1.0 method 1 meth_desc1 {1/{striatum_rate}} call /inputs/striatum/{timetableName} TABFILL end //set up spikegen create spikegen /inputs/striatum/{spikegenName} setfield /inputs/striatum/{spikegenName} output_amp 1 thresh 0.5 //connect timetables to GABA synapses if ({striatum_rate} > 0) addmsg /inputs/striatum/{timetableName} /inputs/striatum/{spikegenName} INPUT activation addmsg /inputs/striatum/{spikegenName} {cellpath}/{striatumcompartment}/{GABAname} SPIKE end end