TITLE Calcium-activated potassium channel
COMMENT
Ca2+-dependent K+ current.
non-voltage-dependent.
Used in Basket, Axoaxonic, Bistratified, CCK+, VIP+/CCK+, and VIP+/CR+ cells.
ENDCOMMENT
NEURON {
SUFFIX gskch
USEION k READ ek WRITE ik
USEION ca READ cai
RANGE gskbar, ek, ik
RANGE beta, factor, qinf, tauq
}
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(S) = (siemens)
(molar) = (1/liter)
(mM) = (millimolar)
}
PARAMETER {
gskbar = 0 (S/cm2)
beta = 0.00025 (/ms)
factor = 1.25e1 (/mM/mM/ms) : unit conversion factor
}
ASSIGNED {
v (mV)
ek (mV)
cai (mM)
ik (mA/cm2)
qinf (1)
tauq (ms)
}
STATE {
q
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = gskbar*pow(q, 2)*(v - ek)
}
DERIVATIVE states {
rates(cai)
q' = (qinf - q)/tauq
}
INITIAL {
rates(cai)
q = qinf
}
PROCEDURE rates(ca (mM)) {
:Computes rate and other constants at current cai.
LOCAL alpha
:"q" activation system
alpha = factor * ca * ca
tauq = 1 / (alpha + beta)
qinf = alpha * tauq
}