TITLE Potassium current
COMMENT
Potassium current for the soma of OLM cells.
ENDCOMMENT
NEURON {
SUFFIX k_olm
USEION k READ ek WRITE ik
RANGE gkbar, ik
RANGE Ra, Rb, vhalf_a, vhalf_b, qa, qb
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(S) = (siemens)
}
PARAMETER {
gkbar = 0 (S/cm2)
Ra = 0.018(/ms)
Rb = 0.0036(/ms)
vhalf_a = 25(mV)
vhalf_b = 35(mV)
qa = 25 (mV)
qb = 12 (mV)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
ninf
taun (ms)
}
STATE {
n
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = gkbar*pow(n, 4)*(v - ek)
}
DERIVATIVE states {
rates(v)
n' = (ninf - n)/taun
}
INITIAL {
rates(v)
n = ninf
}
FUNCTION Exp(x) {
if (x < -100) {
Exp = 0
} else {
Exp = exp(x)
}
}
FUNCTION vtrap(x (mV), y (mV)) (1) {
:Traps for 0 in denominator of rate eqns.
if (fabs(x/y) < 1e-6) {
vtrap = 1(/mV)*y*(1 - x/y/2)
} else {
vtrap = 1(/mV)*x/(Exp(x/y) - 1)
}
}
PROCEDURE rates(v (mV) ) {
:Computes rate and other constants at current v.
LOCAL alpha, beta
alpha = Ra*vtrap(-(v - vhalf_a), qa)
beta = Rb*vtrap(v - vhalf_b, qb)
taun = 1/(alpha + beta)
ninf = alpha*taun
}