TITLE Na persistent channel
: used in distal oblique dendrites to assist Ca spike initiation
: a typo in the exponential function was pointed out by Michele Migliore and
: corrected by Yiota Poirazi on December 4th, 2003
NEURON {
SUFFIX nap
USEION na READ ena WRITE ina
RANGE gnabar,vhalf, K, g, gmax
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER { : parameters that can be entered when function is called in cell-setup
v (mV)
ena = 50 (mV) : Na reversal potential (reset in cell-setup.hoc)
K = 1 (mV) : slope of steady state variable
: gnabar = 0.001e-2 (mho/cm2) : suggested conductance, 1 percent of the transient Na current
gnabar = 0 (mho/cm2) : initialized conductance
vhalf = -51.90 (mV) : half potential
}
STATE { n }
ASSIGNED {
ina (mA/cm2)
g (mho/cm2)
gmax (mho/cm2)
}
INITIAL {
: SOLVE states not used
gmax = 0
}
BREAKPOINT {
states(v)
g = gnabar*n*n*n
ina = g*(v-ena)
if (g > gmax) {
gmax = g
}
}
PROCEDURE states(v (mV)) { : exact when v held constant; integrates over dt step
: n = 1 / (1 + (exp(vhalf - v))/K) : steady state value !!!typo in the exponential function!!!
TABLE n DEPEND vhalf, K FROM -150 TO 150 WITH 300
n = 1 / (1 + exp((vhalf - v)/K)) : steady state value
}