NEURON{ POINT_PROCESS NMDA
RANGE B
GLOBAL mg
}
PARAMETER {
mg = 1. (mM) : external magnesium concentration
Cdur = 1. (ms) : transmitter duration (rising phase)
Alpha = 4. (/ms mM) : forward (binding) rate
Beta = 0.0067 (/ms) : backward (unbinding) rate 1/150
Erev = 0. (mV) : reversal potential
}
ASSIGNED { B }
INCLUDE "netcon.inc"
: EXTRA BREAKPOINT MUST BE BELOW THE INCLUDE
BREAKPOINT {
rates(v)
g = g * B : hence g = gmax * R * B
i = i * B : hence i = g*(v - Erev)
}
PROCEDURE rates(v(mV)) {
TABLE B
DEPEND mg
FROM -100 TO 80 WITH 180
B = 1 / (1 + exp(0.062 (/mV) * -v) * (mg / 3.57 (mM)))
}
:* .INC CHANNELS
:**naf
: again, this conductance was an adaptation of the fast sodium channel
: that was inclused in the Pinsky and Rinzel paper. As is generally
: true of channels modelled in that paper they were drawn from Traub, et.al.
: J Neurophysiol, 1991, 66(2), p.635