TITLE CaL
: L-type Ca current for Retinal Ganglion Cell from Benison et al (2001)
: M.Migliore Nov. 2001
NEURON {
SUFFIX calrgc
USEION ca READ eca WRITE ica
RANGE gbar
GLOBAL minf, mtau
}
PARAMETER {
gbar = 0.010 (mho/cm2)
eca (mV) : must be explicitly def. in hoc
v (mV)
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(pS) = (picosiemens)
(um) = (micron)
}
ASSIGNED {
ica (mA/cm2)
minf mtau (ms)
}
STATE { m }
BREAKPOINT {
SOLVE states METHOD cnexp
ica = gbar*m*m*(v - eca)
}
INITIAL {
trates(v)
m=minf
}
DERIVATIVE states {
trates(v)
m' = (minf-m)/mtau
}
PROCEDURE trates(vm) {
LOCAL a, b
a = trap0(vm,3,0.061,12.5)
b = 0.058*exp(-(vm-10)/15)
minf = a/(a+b)
mtau = 1/(a+b)
}
FUNCTION trap0(v,th,a,q) {
if (fabs(v-th) > 1e-6) {
trap0 = a * (v - th) / (1 - exp(-(v - th)/q))
} else {
trap0 = a * q
}
}