TITLE cardiac calcium pump
: taken from Courtemanche et al Am J Physiol 1998 275:H301
NEURON {
SUFFIX ca_pump
USEION ca READ cao, cai WRITE ica
RANGE IpCamax, ica, ina, ipca
GLOBAL dummy : prevent vectorization for use with CVODE
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
IpCamax = 0.55e-3 (mA/cm2) <0,1e6>
}
ASSIGNED {
celsius (degC)
v (mV)
ica (mA/cm2)
cao (mM)
cai (mM)
ipca (mA/cm2)
dummy
}
BREAKPOINT { LOCAL q10
q10 = 3^((celsius - 37)/10 (degC))
ipca = q10*IpCamax*cai/(0.0005 + cai)
ica = ipca
}