TITLE Potassium ion accumulation
: Intracellular potassium ion accumulation
NEURON {
SUFFIX K_acc
USEION k READ ki, ik WRITE ki
RANGE Vi, Kneutral: electroneutral K accumulation
}
UNITS {
(mV) = (millivolt)
(mM) = (milli/liter)
(mA) = (milliamp)
F = (faraday) (coulombs)
}
PARAMETER {
Vi = 13668e-12 (cm3)
ik (mA/cm2)
Kneutral=3e-5 (mA/cm2) <0,1e6>
}
STATE {
ki START 141.13 (mM)
}
LOCAL ViF
INITIAL {
VERBATIM
ki = _ion_ki;
ENDVERBATIM
ViF = Vi*F*2e4
}
BREAKPOINT {
SOLVE state METHOD derivimplicit
}
DERIVATIVE state {
ki' = -(ik-Kneutral) /(ViF)
}