TITLE SIN current
COMMENT
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Sinusoidal current model for membrane impedance analysis
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IMPLEMENTATION
This mechanism is implemented as a nonspecific current defined as a
point process, mimicking a current-clamp stimulation protocol, injecting
a sinusoidally oscillating waveform I(t).
I(t) = A * sin (2 pi f ( t - ttstart) )
Note:
Since this is an electrode current, positive values of i depolarize the cell and in the
presence of the extracellular mechanism there will be a change in vext since i is not a
transmembrane current but a current injected directly to the inside of the cell.
Note:
This point mechanism has been created by modifying Iclamp..
Refer to: Cali' et al. (2007)
PARAMETERS
This mechanism takes the following parameters:
off (nA) : initial current offset.
del (ms) : initial stimulation latency
dur (ms) : duration of the stimulation
amp (nA) : amplitude of the stimulation
freq (Hz) : frequency of the sinusoidal current.
Written by M. Giugliano and C. Cali', Brain Mind Institute, EPFL, March 2006
Modified by C. Cali', Brain Mind Institute, EPFL, April 2006
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ENDCOMMENT
NEURON {
POINT_PROCESS Isin
RANGE del, dur, amp, i, freq, off
ELECTRODE_CURRENT i
}
UNITS {
(nA) = (nanoamp)
}
PARAMETER {
off (nA)
del (ms)
dur (ms) <0,1e9>
amp (nA)
freq (Hz)
}
ASSIGNED { i (nA) }
INITIAL {
i = 0
}
BREAKPOINT {
at_time(del)
at_time(del+dur)
if (t < del + dur && t >= del) {
i = off + amp * sin(0.0062831853071795866*freq*t)
}else{
i = off
}
}