TITLE Calcium dependent potassium channel (small conductance SK)
UNITS {
(molar) = (1/liter)
(mV) = (millivolt)
(S) = (siemens)
(mA) = (milliamp)
(mM) = (millimolar)
}
NEURON {
SUFFIX kcas
USEION ca READ cai
USEION k WRITE ik
RANGE gk,gbar,km,oinf,ik,n,otau
:POINTER cap
}
PARAMETER {
cai (mM)
gbar (S/cm2)
gk (S/cm2)
ek = -90 (mV)
km = 0.00019 (mM)
n = 4.0 (1)
otau=28 (ms)
}
ASSIGNED {
v (mV)
ik (mA/cm2)
oinf (1)
:cap
}
BREAKPOINT {
SOLVE states METHOD cnexp
if (cai>0) {
oinf = 1/(1 + pow(km/cai,n))
} else {
oinf=0
}
:ik = oinf*gbar*(v - ek)
ik = o*gbar*(v - ek)
gk = o*gbar
}
STATE { o <1e-4>}
INITIAL {
o = 1/(1 + pow(km/cai,n))
}
UNITSOFF
DERIVATIVE states {
if (cai>0) {
oinf = 1/(1 + pow(km/cai,n))
} else {
oinf=0
}
o' = (oinf-o)/otau
}
UNITSON