## Synaptic and circuit mechanisms prevent detrimentally precise correlation in the developing mammalian visual system
by _Ruben A. Tikidji-Hamburyan, Gubbi Govindaiah, William Guido, Matthew T. Colonnese_
eLife 2023; 12:e84333. DOI: https://doi.org/10.7554/eLife.84333.
### Required software
For any simulation in this record, one needs `Python`(version 3.9.9 and higher) and libraries `cython`, `numpy`, `scipy` and `matplotlib`.
```bash
$pip3 install --user numpy scipy matplotlib cython
```
Additional libraries:
| | |
|:-----------------|:----------------------------------------|
|Figure 1 | `NEURON`, `pyabf` and `inspyred` |
|Figure 2,4,5 | `NEURON`, `h5py`, and `neurodsp` |
To install all libraries for all scripts, use a single command
```bash
$pip3 install --user numpy scipy matplotlib cython NEURON pyabf inspyred h5py neurodsp brian2
```
### Files, directories, and models in this record
|File or directory | Description |
|:---------------------------|:----------------------------------------------------------------------|
|[TC-fitting](https://senselab.med.yale.edu/modeldb/ShowModel?model=267589&file=/dLGN-decorrelation-2023/TC-fitting/README.html#tabs-2) | Fitting procedure and associated files for Figure 1 in the manuscript |
|[dLGN-network](https://senselab.med.yale.edu/modeldb/ShowModel?model=267589&file=/dLGN-decorrelation-2023/dLGN-network/README.html#tabs-2) | Thalamic network at P7-P10 for Figures 2, 4, and 5 in the manuscript |
|experimentaldata | an example of a neuron recording and mask file for the optimization as well as Maccione et al. 2014 recording from [_waverepo_ repository on GitHub](https://github.com/sje30/waverepo) |
|[P07-selected-checked-gmin-20220921.json](https://github.com/rat-h/DevelopmentOfThalamocorticalNeurons) | A reduced, fully validated, and human-evaluated database of 286 models of thalamocortical neurons in visual LGN at P7-P10, enough to reproduce any results in the manuscript |