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%
% classPyramidal includes all proprieties and methods specific for
% pyramidal cells.
%
% Licurgo de Almeida
% 04/29/2013
%
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
classdef classPyramidal < classSpkNeuron
properties
% from Mitral cells
AMPAFf % struct with parameters from the excitatory synapses
ConnAMPAFf = 0.2; % percentage of pyr cells connected to each
% mitral
MAMPAFf % connection matrix with the mitral cells
WAMPAFf % synaptic weight matrix with the mitral cells
% from Feed forward interneurons
GABAFf % struct with parameters from the inhibitory synapses
ConnGABAFf = 0.3; % percentage of Ff cells connected to each
% pyramidal cell
MGABAFf % connection matrix with the Feedforward interneurons
WGABAFf % synaptic weight matrix with the Feedforward interneurons
% from Pyramidal cells
AMPAFb % struct with parameters from the excitatory synapses
ConnAMPAFb = 0.2; % percentage of pyr cells connected to each
% other
MAMPAFb % connection matrix with the pyramidal cells
WAMPAFb % synaptic weight matrix with the pyramidal cells
% from Feedback interneurons
GABAFb % struct with parameters from the inhibitory synapses
ConnGABAFb = 0.4; % percentage of feedback cells connected to each
% pyramidal cell
MGABAFb % connection matrix with the Feedback interneurons
WGABAFb % synaptic weight matrix with the Feedback interneurons
% from AHP
EAHP = -15e-3; % reversal potential for after hyperpolarization
% potential
AAHP = 16; % amplitude of the hyperpolarization potential
tauAHP = 20; % falling time of the hyperpolarization potential
% from learning
Tau11 = 200; %ms
Tau01 = 200; %ms
Tau10 = 200; %ms
Taupost = 2; %ms
Tauf = 7; %ms
Taur = 1; %ms
Tdelay = 1; %ms
end
methods
function obj = classPyramidal(tsim,ncells)
if nargin == 0
inputsuper = {};
else
inputsuper = {tsim,ncells};
end
obj = obj@classSpkNeuron(inputsuper{:});
obj.tau = 10; %ms
obj.CellName = 'Pyramidal';
obj.AMPAFf = struct('E',70e-3,'tau1',1,'tau2',2,'G',0.38);
% where the elements of the struct are:
% E: reversal potential
% tau1: rising time of the conductance
% tau2: falling time of the conductance
% G: max conductance
obj.MAMPAFf = obj.SetConnections(obj.ncells,obj.ConnAMPAFf,'normal');
obj.WAMPAFf = obj.MAMPAFf;
obj.GABAFf = struct('E',-15e-3,'tau1',4,'tau2',8,'G',0.38);
obj.MGABAFf = obj.SetConnections(obj.ncells,obj.ConnGABAFf);
obj.WGABAFf = obj.MGABAFf;
obj.AMPAFb = struct('E',70e-3,'tau1',1,'tau2',2,'G',[4.5,1.8]);
% AMPAFb.G changes with ACh modulation
obj.MAMPAFb = obj.SetConnections(obj.ncells,obj.ConnAMPAFb,'auto');
obj.WAMPAFb = rand(size(obj.MAMPAFb)) .* obj.MAMPAFb * 0.01; % autoassociative
% connection weights start with 0
obj.GABAFb = struct('E',-15e-3,'tau1',4,'tau2',8,'G',[200e-3,70e-3]);
obj.MGABAFb = obj.SetConnections(obj.ncells,obj.ConnGABAFb);
obj.WGABAFb = obj.MGABAFb;
end
end
end